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2-(Trimethylsilyloxy)ethanamine

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Identification
Molecular formula
C5H15NO1Si
CAS number
107-42-6
IUPAC name
2-trimethylsilyloxyethanamine
State
State
At room temperature, 2-(Trimethylsilyloxy)ethanamine is typically in a liquid state, making it suitable for various liquid-phase reactions.
Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
102.00
Boiling point (Kelvin)
375.15
General information
Molecular weight
145.27g/mol
Molar mass
145.2850g/mol
Density
0.8290g/cm3
Appearence

2-(Trimethylsilyloxy)ethanamine is a clear, colorless liquid. It is often used in organic synthesis and may have an amine-like odor.

Comment on solubility

Solubility of 2-trimethylsilyloxyethanamine

2-trimethylsilyloxyethanamine, with its unique structure, exhibits interesting solubility characteristics. This compound features a trimethylsilyloxy group, which significantly influences its interaction with solvents. Its solubility can be explored in various contexts:

  • Polar Solvents: Typically, compounds with amino groups, such as 2-trimethylsilyloxyethanamine, tend to be soluble in polar solvents due to hydrogen bonding. This compound likely demonstrates good solubility in water and alcohols.
  • Nonpolar Solvents: The presence of the trimethylsilyl group may enhance its solubility in certain nonpolar solvents. This dual nature can be advantageous for specific applications.
  • Temperature Effects: Temperature plays a crucial role in the solubility of this compound. Higher temperatures generally increase solubility, allowing more of the compound to dissolve in a solvent.

In conclusion, 2-trimethylsilyloxyethanamine's unique structure allows it to have diverse solubility properties, making it suitable for various chemical environments. Its solubility profile is essential for understanding its applications in chemical synthesis and material science.

Interesting facts

Interesting Facts about 2-Trimethylsilyloxyethanamine

2-Trimethylsilyloxyethanamine, often abbreviated as TMS-ethanamine, is a fascinating compound with a range of unique properties and applications in the field of chemistry. Here are some noteworthy points about this compound:

  • Versatile Reactivity: This compound is known for its ability to react with various electrophiles, making it a valuable intermediate in organic synthesis.
  • Silyl Group Significance: The trimethylsilyl (TMS) group enhances the stability and reactivity of certain functional groups, paving the way for innovative methodologies in synthetic chemistry.
  • Biological Relevance: Compounds with a similar structure have been explored for potential applications in medicinal chemistry, particularly in relation to the development of new pharmaceuticals.
  • Facilitates Analysis: The presence of the TMS group aids in the analysis of compounds using techniques like gas chromatography and mass spectrometry.
  • Synthetic Utility: TMS-ethanamine can serve as a useful building block for larger, more complex molecules, highlighting its significance in the realm of synthetic organic chemistry.

Furthermore, this compound also emphasizes the broader implications of organosilicon chemistry, which continues to play a pivotal role in the development of advanced materials and technologies. As chemists explore new pathways and methods for synthesis, compounds like 2-trimethylsilyloxyethanamine will undoubtedly remain in the spotlight for their versatility and potential.

Synonyms
(2-Aminoethoxy)trimethylsilane
857-892-7
5804-92-2
2-TRIMETHYLSILANYLOXY-ETHYLAMINE
2-trimethylsilyloxyethanamine
2-(Trimethylsiloxy)ethylamine
Ethanamine, 2-[(trimethylsilyl)oxy]-
Ethanamine, 2-((trimethylsilyl)oxy)-
O-(Trimethylsilyl)ethanolamine
BRN 1734571
2-(Trimethylsilyloxy)ethylamine
Silane, (2-aminoethoxy)trimethyl-
Aminoethanol, O-TMS
ETHYLAMINE, 2-(TRIMETHYLSILOXY)-
Ethanamine, 2-((trimethylsilyl)oxy)- (9CI)
4-04-00-04006 (Beilstein Handbook Reference)
2-(trimethylsilyloxy)ethanamine
SCHEMBL1484804
DTXSID20206764
MFCD01726954
AKOS006280169
DB-006225
EN300-93871
F78442