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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
20-[(2R,5R)-4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,6,11,12,16,18,36-heptahydroxy-35,37,38-trimethyl-2,8,14-trioxo-1-oxacyclooctatriaconta-21,23,25,27,29,31,33-heptaene-17-carboxylic acid
State
State

At room temperature, erythromycin is typically in a solid state, often found as a powder or in pharmaceutical formulations.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2400g/cm3
Appearence

Erythromycin appears as a white to off-white, crystalline powder. It is often formulated as tablets or ointments for medicinal use. The powder is practically odorless.

Comment on solubility

Solubility of 20-[(2R,5R)-4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,6,11,12,16,18,36-heptahydroxy-35,37,38-trimethyl-2,8,14-trioxo-1-oxacyclooctatriaconta-21,23,25,27,29,31,33-heptaene-17-carboxylic acid

The solubility of this complex organic compound can be quite intriguing, given its multifaceted structure. Several factors play a crucial role in determining how well it dissolves in various solvents:

  • Polarity: The presence of multiple hydroxyl groups and a carboxylic acid functional group suggests potential for significant interaction with polar solvents, such as water, allowing the compound to be more soluble in these environments.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to -OH and -NH groups enhances solubility in protic solvents, aiding in the dissolution process.
  • Hydrophobic Regions: The presence of hydrophobic hydrocarbon chains may hinder solubility in highly polar solvents; thus, this compound may exhibit varied solubility depending on the solvent environment.
  • Concentration Effects: At higher concentrations, solubility may decrease, leading to precipitation when the solvent cannot accommodate additional solute due to saturation limits.

In summary, while the structural attributes of this compound suggest a proclivity towards solubility in polar solvents, the specific solubility behavior can greatly vary. It is essential to consider the medium's polarity, temperature, and pH to accurately assess solubility characteristics. As with many complex compounds, the interplay of various functional groups creates a fascinating dynamic in understanding solubility.

Interesting facts

Interesting Facts About the Compound

The compound known as 20-[(2R,5R)-4-amino-3,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4,6,11,12,16,18,36-heptahydroxy-35,37,38-trimethyl-2,8,14-trioxo-1-oxacyclooctatriaconta-21,23,25,27,29,31,33-heptaene-17-carboxylic acid is a fascinating example of organic chemistry showcasing complex molecular architecture. Here are some captivating insights about this remarkable compound:

  • Structural Complexity: This compound possesses a highly intricate structure, featuring multiple functional groups and stereocenters. Its elaborate composition makes it a subject of interest in the field of synthetic and medicinal chemistry.
  • Biological Relevance: Many compounds similar to this one have found applications in pharmaceuticals, particularly in therapeutic areas such as cancer treatment and antimicrobial research, highlighting the importance of understanding such structures in drug design.
  • Intriguing Stereochemistry: The presence of specific stereogenic centers (notably in the tetrahydropyran portion) underscores the significance of stereochemistry in biological activity, emphasizing that the spatial arrangement of atoms can greatly influence a compound’s properties.
  • Potential Applications: Researchers are continuously exploring compounds like this one for their potential in creating novel therapeutic agents. The complexity of the molecule allows scientists to fine-tune it for specific biological interactions.

As we delve deeper into the structure and functionality of compounds like this, we not only expand our knowledge of chemistry but also pave the way for innovative approaches to tackling some of the most pressing health challenges of our time. "Chemistry is the fabric of reality," a quote that resonates particularly well here, as understanding these intricate compounds might lead to breakthroughs that impact lives around the globe.