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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[[(4-methylpiperazin-1-yl)amino]methylene]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,24,27-octaen-13-yl] acetate
State
State

At room temperature, erythromycin is typically in a solid state. It may be rendered as tablets, capsules, or in powder form for pharmaceutical applications. As a solid, it is easily handled and stored, though care must be taken to avoid excessive moisture and light to prevent degradation.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
206.00
Boiling point (Kelvin)
479.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.2400g/cm3
Appearence

Erythromycin appears as a white to off-white powder. It is usually crystalline in form and is odorless. The compound is stable and shows some level of solubility in organic solvents but is poorly soluble in water. It may exhibit a slight yellow tint when in its powdered form under certain conditions.

Comment on solubility

Solubility of 2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[[(4-methylpiperazin-1-yl)amino]methylene]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,24,27-octaen-13-yl Acetate (C37H67NO13)

The compound C37H67NO13 showcases a complex structure replete with multiple functional groups, influencing its solubility profile significantly. Below are some key considerations to keep in mind regarding its solubility:

  • Polar and Non-Polar Interactions: This compound contains several hydroxyl (-OH) and methoxy (-OCH3) groups, which are typically polar and enhance solubility in polar solvents, such as water. Conversely, the long alkyl chains suggest that it may also have some affinity for non-polar solvents.
  • Hydrogen Bonding: The abundant hydroxyl groups can engage in hydrogen bonding, increasing interaction with solvents that can also act as hydrogen bond donors or acceptors.
  • Effect of pH: The pH of the surrounding environment could potentially affect the ionization of the compound, impacting its solubility. For instance, in a more acidic or basic medium, certain functional groups may become protonated or deprotonated, enhancing or diminishing solubility respectively.
  • Solvent Compatibility: Likely, the compound will exhibit moderate solubility in common organic solvents like ethanol or methanol, while displaying limited solubility in aliphatic hydrocarbons.

In summary, the solubility of C37H67NO13 is a multifaceted attribute influenced by its intricate functional groups and the nature of the solvent. Testing in various solvents will yield a comprehensive understanding of its solubility characteristics, making it critical for applications in pharmacology and materials science.

Interesting facts

Interesting Facts about 2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[[(4-methylpiperazin-1-yl)amino]methylene]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,24,27-octaen-13-yl acetate

This compound, with a complex structure, reflects the remarkable diversity of organic chemistry and its applications in various fields. Here are some fascinating insights about it:

  • Multifunctional Properties: The presence of multiple hydroxyl groups indicates that this compound could exhibit significant solubility and reactivity, making it a candidate for various chemical reactions.
  • Pharmacological Potential: The inclusion of a piperazine moiety suggests that the compound could potentially interact with biological systems, as piperazine derivatives are often found in numerous pharmaceuticals.
  • Structural Complexity: The intricate arrangement of atoms and functional groups showcases the compound's stereochemical diversity, which is crucial in the design of molecules with targeted biological activity.
  • Applications in Research: Compounds like this can serve as valuable tools in drug design and discovery, providing insights into the interactions between complex molecules and biological targets.
  • Analog Design: Scientists might use such compounds to create analogs that could yield better therapeutic efficacy or reduced side effects by modifying specific parts of the molecule.

Understanding the behavior of this compound can unveil new perspectives in synthetic organic chemistry and medicinal chemistry, paving the way for innovations in drug development and tailored therapeutic agents. As a scientist delving into its chemistry, one can only be excited about the possibilities that such a unique compound presents.