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2,2-bis(4-nitrophenoxy)acetic acid

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Identification
Molecular formula
C14H10N2O8
CAS number
29305-12-6
IUPAC name
2,2-bis(4-nitrophenoxy)acetic acid
State
State

At room temperature, 2,2-bis(4-nitrophenoxy)acetic acid is in a solid state. Its solid form is stable under normal conditions and is often handled as a powder. Care should be taken to prevent its decomposition through methods like strong heat or light exposure.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
370.27g/mol
Molar mass
370.2730g/mol
Density
1.5600g/cm3
Appearence

2,2-bis(4-nitrophenoxy)acetic acid typically appears as a pale-yellow crystalline solid. The crystals are often described as slightly glossy or sparkly under light due to their structure. This compound's coloration comes from the nitro groups attached to the phenoxy rings, which impart the yellowish hue.

Comment on solubility

Solubility of 2,2-bis(4-nitrophenoxy)acetic acid

2,2-bis(4-nitrophenoxy)acetic acid, a compound with a complex structure, showcases interesting solubility characteristics that are influenced by its functional groups. Here are some key points about its solubility:

  • Polar Nature: The presence of nitro groups and the carboxylic acid functionality contributes to its polarity, enhancing solubility in polar solvents.
  • Solvents:
    • It is generally soluble in polar solvents such as water, ethanol, and dimethyl sulfoxide (DMSO).
    • Solubility may be limited in non-polar solvents like hexane or toluene.
  • pH Dependence: The solubility can increase significantly in basic solutions, where the carboxylic acid group is deprotonated, leading to the formation of a more soluble anionic species.
  • Concentration Effects: At higher concentrations, solubility might decrease due to aggregation or precipitation phenomena.

In summary, the solubility of 2,2-bis(4-nitrophenoxy)acetic acid is influenced by its functional groups, with a tendency to favor solubility in polar environments while showcasing variability with changes in pH and concentration. Understanding these solubility behaviors is crucial for its application and handling in various chemical processes.

Interesting facts

Interesting Facts about 2,2-bis(4-nitrophenoxy)acetic Acid

2,2-bis(4-nitrophenoxy)acetic acid is a fascinating compound that combines properties from both organic chemistry and medicinal applications. This compound is particularly notable for its structure, which features two nitrophenoxy groups attached to a central acetic acid backbone, giving it unique chemical and biological profiles.

Key Highlights:

  • Antibacterial Properties: Research indicates that this compound can exhibit antibacterial activity, making it a subject of interest for the development of new antimicrobial agents.
  • Potential Applications: It has been explored in various fields, including agrochemicals and pharmaceuticals, thanks to its ability to interact with biological systems effectively.
  • Structure-Activity Relationship (SAR): The presence of nitro groups plays a crucial role in enhancing the biological activity of the compound, making it a valuable model for studying how substituents can influence drug efficacy.
  • Environmental Impact: Understanding the stability and breakdown products of this compound is essential for evaluating its environmental safety and potential accumulation in ecosystems.

As someone involved in the study of chemical compounds, you will find that 2,2-bis(4-nitrophenoxy)acetic acid serves as an excellent example of how structural modifications can lead to significant variations in chemical behavior and biological activity. Researchers continue to explore its potential, which opens up avenues for innovation in both chemical and pharmaceutical industries. As a chemistry student, one might reflect on the importance of such compounds in shaping future therapeutic strategies by saying: "The beauty of chemistry lies not only in its complexity but in its immense potential for practical applications."

Synonyms
Bis(p-nitrophenoxy)acetic acid
ACETIC ACID, BIS(p-NITROPHENOXY)-
BRN 3470380
27124-56-7
DTXSID20181587
0-06-00-00235 (Beilstein Handbook Reference)
RefChem:316560
DTXCID60104078