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BPA (Bisphenol A)

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Identification
Molecular formula
C16H16O2
CAS number
6402-23-9
IUPAC name
2,2-bis(p-tolyl)acetic acid
State
State

Solid at room temperature.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
570.00
Boiling point (Kelvin)
843.15
General information
Molecular weight
242.32g/mol
Molar mass
242.3160g/mol
Density
1.1900g/cm3
Appearence

2,2-bis(p-tolyl)acetic acid is a white to off-white crystalline solid.

Comment on solubility

Solubility of 2,2-bis(p-tolyl)acetic Acid

The solubility of 2,2-bis(p-tolyl)acetic acid in various solvents is an intriguing aspect of its chemical behavior. This compound, characterized by its bulky and hydrophobic p-tolyl groups, presents a unique solubility profile:

  • Solvent Compatibility: Due to its aromatic structure, 2,2-bis(p-tolyl)acetic acid is expected to show higher solubility in organic solvents. For instance:
    • It may dissolve well in ethyl acetate, toluene, and other non-polar solvents.
    • Limited solubility in polar solvents, such as water, is anticipated.
  • Club of Solubility: Considerations regarding its solubility can be categorized into various factors:
    • Temperature: Increased temperatures often lead to greater solubility in organic solvents.
    • pH Levels: The acidity or basicity of the solution may influence ionization, affecting solubility in aqueous environments.
    • Hydrophobic Interactions: The presence of bulky p-tolyl groups may hinder hydrogen bonding with water, further reducing solubility.

The balance of these factors hints at a fascinating interplay: while 2,2-bis(p-tolyl)acetic acid may exhibit moderate solubility in specific organic solvents, its behavior in aqueous environments may be limited. Understanding this solubility behavior is crucial for applications in fields such as organic synthesis and pharmaceutical formulation.

Interesting facts

Interesting Facts about 2,2-bis(p-tolyl)acetic acid

2,2-bis(p-tolyl)acetic acid is a fascinating compound that belongs to the family of bisarylacetic acids. Its distinctive structure and unique properties make it a subject of interest among chemists and researchers alike.

Key Characteristics:

  • Structural Signature: This compound features two p-tolyl groups connected to a central acetic acid moiety, resulting in a complex three-dimensional structure that is intriguing for molecular modeling studies.
  • Biological Relevance: Research has indicated that compounds like 2,2-bis(p-tolyl)acetic acid may play roles in various biological systems, prompting investigations into their pharmacological properties.
  • Synthetic Versatility: The synthesis of this compound showcases the versatility of organic reactions, particularly in terms of coupling reactions that can introduce substituents in a controlled manner.

Benefits and Applications:

  • Potential Drug Development: Its unique structure may lead to the development of novel pharmaceuticals.
  • Industrial Uses: Useful in formulations that require specific chemical properties for effective performance.

Moreover, working with 2,2-bis(p-tolyl)acetic acid offers chemists an opportunity to explore numerous reaction pathways and mechanisms. As a result, 2,2-bis(p-tolyl)acetic acid serves as an excellent teaching example of how organic chemistry principles can be applied to create compounds with practical applications.
It’s essential to note that understanding this compound's properties can not only enrich the field of synthetic organic chemistry but also spark discussions about its potential as a pivotal ingredient in various chemical processes.

Synonyms
Di-p-tolylacetic acid
20809-78-3
Bis(p-tolyl)-acetic acid
2,2-bis(4-methylphenyl)acetic acid
Acetic acid, di-p-tolyl-
ACETIC ACID, BIS(p-TOLYL)-
2,2-Bis(p-tolyl) acetic acid
NSC-13678
Benzeneacetic acid, 4-methyl-alpha-(4-methylphenyl)-
NSC13678
NSC 13678
BRN 2051315
Cambridge id 5135276
6KV65LE9FJ
Oprea1_228951
2,2-bis(p-tolyl)acetic acid
bis(4-methylphenyl)acetic acid
WLN: QVYR D1&R D1
SCHEMBL1502454
DTXSID30174920
DRVBWVSGMCHHOU-UHFFFAOYSA-N
DS-010826
AB00074265-01
4-09-00-02557 (Beilstein Handbook Reference)
SR-01000196547
SR-01000196547-1
Benzeneacetic acid, 4-methyl-.alpha.-(4-methylphenyl)-