Interesting facts
Interesting Facts About 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-methylsulfonylphenyl)ethyl]acetamide
This fascinating compound, commonly referred to in the scientific community due to its *unique structure and functionality*, showcases the exciting interplay of medicinal chemistry and structural biology. Here are some intriguing facts about this compound:
- Pharmaceutical Applications: 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-methylsulfonylphenyl)ethyl]acetamide is recognized for its potential therapeutic benefits. As a derivative of common acetamides, its structural modifications may offer distinct advantages in drug design and synthesis.
- Chirality Matters: The designation of (1R,2R) indicates the compound's chirality, which is a critical aspect in pharmaceutical development. Chirality can influence *biological activity* and *metabolism*, making the understanding of stereochemistry essential for drug efficacy.
- Chemical Stability: The inclusion of dichloro groups in its molecular structure can enhance the compound's stability, which is crucial for its performance as a pharmaceutical agent. This stability may allow for effective *sustained release* and durability in diverse chemical environments.
- Structural Complexity: The presence of a sulfonyl group linked to a phenyl ring contributes to the compound's multi-faceted nature. This structural integrity often leads to varied biological interactions and could be a target for further research.
- Research Potential: Ongoing studies into the mechanisms through which this compound interacts with biological systems could yield significant insights. It exemplifies how *organic modifications* can lead to innovations in treatment strategies for complex health conditions.
In conclusion, the compound's distinct characteristics and its potential roles in medicinal chemistry make it a compelling subject for both researchers and chemists alike. The emphasis on structural intricacies and biological relevance underpins the importance of continued exploration in this field.
Synonyms
thiamphenicol
15318-45-3
Thiophenicol
Thiocymetin
(+)-Thiamphenicol
Urfamycine
Igralin
Dextrosulphenidol
Thiamphenicolum
Tiamfenicol
Tiamfenicolo
Armai
WIN-5063-2
Descocin
Macphenicol
Masatirin
Neomyson
Urfamicina
Efnicol
Hyrazin
Rincrol
tianfenicol
FLQ7571NPM
CCRIS 8588
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
DTXSID5021338
CHEBI:32215
Methylsulfonylchloramphenicol
NSC-522822
2,2-dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide
DTXCID801338
Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R-(R*,R*))-
Dextrosulfenidol
2,2-DICHLORO-N-((1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-(METHYLSULFONYL)PHENYL)ETHYL)ACETAMIDE
2,2-dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl)acetamide
GlyTouCan:G80355IB
J01BA02
G80355IB
CB-8053
(alphaR,betaR)-2,2-Dichloro-N-(beta-hydroxy-alpha-hydroxymethyl-4-methylsulphonylphenethyl)acetamide
239-355-3
Thiocymetin (TN)
Thiamphenicol (Thiophenicol)
Armai (TN)
Dexawin
Racephenicol [USAN]
MFCD00467983
Racefenicol [INN]
C12H15Cl2NO5S
MLS001332640
D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide
Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-
SMR000857096
D-Thiocymetin
D-Thiophenicol
2,2-dichloro-N-((1R,2R)-1,3-dihydroxy-1-(4-(methylsulfonyl)phenyl)propan-2-yl)acetamide
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide
Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-
Tiamfenicolo [DCIT]
Thiamphenicol dl-form
WIN 5063-2
Tiamfenicol [INN-Spanish]
Thiamphenicolum [INN-Latin]
8065 C.B.
Racefenicolo [DCIT]
(+/-)-Thiamphenicol
SR-05000001829
Thiophenicol;Dextrosulphenidol
EINECS 239-355-3
Thiamphenicol [USAN:INN:BAN:JAN]
UNII-FLQ7571NPM
NSC 522822
Racefenicolum [INN-Latin]
UNII-283383NO13
NCGC00016714-01
Prestwick_885
CAS-15318-45-3
Spectrum_001428
Thiamphenicol (Standard)
Prestwick0_000025
Prestwick1_000025
Prestwick2_000025
Prestwick3_000025
Spectrum2_000856
Spectrum3_001562
Spectrum4_000733
Spectrum5_001617
THIAMPHENICOL [MI]
D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol
D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol
THIAMPHENICOL [INN]
THIAMPHENICOL [JAN]
THIAMPHENICOL [USAN]
SCHEMBL34635
BSPBio_000089
BSPBio_003064
KBioGR_001026
KBioSS_001908
cid_27200
MLS001332639
MLS002154177
DivK1c_000842
SPECTRUM1503136
THIAMPHENICOL [MART.]
SPBio_000871
SPBio_002010
THIAMPHENICOL [WHO-DD]
BPBio1_000099
orb1308224
CHEMBL1236282
Thiamphenicol (JAN/USAN/INN)
BDBM58925
GTPL12400
HMS502K04
HY-B0479R
KBio1_000842
KBio2_001908
KBio2_004476
KBio2_007044
KBio3_002564
MSK7002
NINDS_000842
Thiamphenicol, analytical standard
HMS1568E11
HMS1922G19
HMS2092L18
HMS2095E11
HMS2232E21
HMS3712E11
Pharmakon1600-01503136
THIAMPHENICOL DL-FORM [MI]
BCP32746
HY-B0479
THIAMPHENICOL [EP MONOGRAPH]
Tox21_110577
Tox21_200816
CCG-40309
NSC758396
s2583
AKOS015951269
dl-threo-2-Dichloroacetamido-1-(4-methylsulfonyl-phenyl)-1,3-propanediol
Tox21_110577_1
DB08621
NSC-758396
IDI1_000842
SMP2_000125
NCGC00178319-01
NCGC00178319-02
NCGC00178319-03
NCGC00178319-06
NCGC00178319-07
NCGC00258370-01
(+-)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide
Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)-, D-threo-(+)
Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)-, threo-(+-)-
AS-12501
SY073192
SBI-0051779.P002
NS00098623
SW197006-3
T2802
Thiamphenicol 1000 microg/mL in Acetonitrile
D01407
AB00052321_10
AB00052321_11
Q425015
SR-05000001829-1
SR-05000001829-3
BRD-K79711234-001-06-8
BRD-K79711234-001-11-8
BRD-K79711234-001-17-5
BRD-K79711234-001-18-3
Thiamphenicol, European Pharmacopoeia (EP) Reference Standard
Thiophenicol; Dextrosulphenidol; Descocin; Hyrazin; Masatirin; Urfamycine
2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-[4-(methylsulfonyl)phenyl]-2-propyl]acetamide
2,2-dichloro-N-[(1R,2R)-2-hydroxy-2-(4-mesylphenyl)-1-methylol-ethyl]acetamide
2,2-bis(chloranyl)-N-[(1R,2R)-1-(4-methylsulfonylphenyl)-1,3-bis(oxidanyl)propan-2-yl]ethanamide
2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-methylsulfonylphenyl)ethyl]acetamide
Acetamide, 2,2-dichloro-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, rel-
ACETAMIDE, 2,2-DICHLORO-N-(.BETA.-HYDROXY-.ALPHA.-(HYDROXYMETHYL)-P-(METHYLSULFONYL)PHENETHYL)-, THREO-(+/-)-
Acetamide, 2,2-dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-(methylsulfonyl)phenyl)ethyl)-, (R*,R*)-(+-)-
ACETAMIDE, 2,2-DICHLORO-N-(2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-(METHYLSULFONYL)PHENYL)ETHYL)-, (R*,R*)-(+/-)-
D-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-[hydroxymethyl]-4-[methylsulfonyl]phenethyl)acetamide
TH8
Solubility of 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-methylsulfonylphenyl)ethyl]acetamide
The solubility of 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-methylsulfonylphenyl)ethyl]acetamide can be influenced by various factors related to its chemical structure. Here are some key points to consider:
In summary, the solubility of this compound is multi-faceted and governed by its unique structure. Factors like polarity, solvent choice, temperature, and pH play crucial roles in determining how well it can dissolve, making it an intriguing subject for further investigation.