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Salicylanilide acetic acid ester

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Identification
Molecular formula
C10H11Cl2NO3
CAS number
3567-94-0
IUPAC name
2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide
State
State

At room temperature, this compound is typically found in a solid state, exhibiting a crystalline nature.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.00
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.00
General information
Molecular weight
260.10g/mol
Molar mass
260.1040g/mol
Density
1.4961g/cm3
Appearence

2,2-Dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide is typically a white to off-white crystalline powder. Its purity and specific appearance may vary based on production and handling conditions.

Comment on solubility

Solubility of 2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide

The solubility of 2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide can be influenced by various factors including its chemical structure and the nature of the solvent. Understanding its solubility is crucial for applications in pharmaceuticals and chemical synthesis.

Key Points on Solubility:

  • Polar Characteristics: The presence of hydroxyl (-OH) groups in the compound enhances its ability to interact with polar solvents such as water, resulting in increased solubility.
  • Hydrophobic Interactions: The dichloro and aromatic components may contribute some hydrophobic characteristics, potentially decreasing solubility in highly polar solvents.
  • Temperature Dependence: Solubility can be temperature-dependent; an increase in temperature may lead to higher solubility in organic solvents.
  • pH Influence: The solubility might also vary with pH, particularly due to the presence of hydroxyl functionalities that can ionize under certain conditions.

In summary, while 2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide is likely soluble in polar solvents, its solubility may vary widely depending on environmental conditions and the nature of the solvent employed. Therefore, it is essential to consider these factors when predicting its behavior in practical applications.

Interesting facts

Interesting Facts about 2,2-Dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide

2,2-Dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide, often referred to as a member of the chlorinated acetamide family, presents several intriguing characteristics that are of significant interest in the fields of chemistry and pharmacology. Below are some fascinating points about this compound:

  • Pharmacological Relevance: This compound exhibits potential pharmaceutical properties that may be explored for therapeutic applications. Its structure, particularly the dichloro group, is known to influence biological activity.
  • Synthetic Pathways: The synthesis of this compound may involve various reactions, including chlorination and amide bond formation. Understanding these synthetic routes is crucial for developing various derivatives.
  • Research Applications: Due to its unique chemical properties, it can be utilized in various research settings, particularly in studying drug interactions, metabolism, and toxicology.
  • Solvent Effects: The presence of hydroxyethyl and hydroxyphenyl groups within its structure may lead to interesting interactions with solvents and other reagents, thus influencing its reactivity and stability.
  • Environmental Considerations: As a chlorinated compound, it is essential to study its environmental impact. Research in this area can help assess the ecological risks associated with its use and disposal.

In summary, the exploration of 2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide provides a vast landscape for inquiry within chemistry. As we delve deeper into its characteristics and potential applications, this compound may reveal important insights that are valuable not just to chemists, but to many scientific disciplines.

Synonyms
3613-84-1
ACETANILIDE, 2,2-DICHLORO-2'-HYDROXY-N-(2-HYDROXYETHYL)-
M & B 4897
BRN 2813295
2,2-Dichloro-N-(2-hydroxyethyl)-2'-hydroxyacetanilide
DTXSID00189708
DTXCID20112199
2,2-dichloro-N-(2-hydroxyethyl)-N-(2-hydroxyphenyl)acetamide
starbld0047350
AKOS040750079