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Acetaminophen (with dichloro substitution)

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Identification
Molecular formula
C9H9Cl2NO2
CAS number
/
IUPAC name
2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide
State
State

At room temperature, this compound is a solid.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
216.07g/mol
Molar mass
216.0660g/mol
Density
1.2150g/cm3
Appearence

This compound generally appears as a solid, typically in a crystalline form. The presence of chlorine atoms may impart a pale yellow hue.

Comment on solubility

Solubility of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide

The solubility of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide is influenced by various factors that govern the behavior of organic compounds in solvents. Understanding its solubility can provide insights into its potential applications and interactions in different environments.

  • Polarity: Due to the presence of both hydrophobic (chloro and methyl groups) and hydrophilic (hydroxyl group) components, the compound exhibits moderate polarity, affecting its solubility in water and organic solvents.
  • Solvent Type: This compound is likely to be more soluble in non-polar to mildly polar organic solvents, such as ethanol or ethyl acetate, while its solubility in water may be limited.
  • Temperature Influence: As with many organic compounds, solubility can increase with temperature. This is crucial for applications requiring higher concentrations.

In summary, while 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide is expected to be sparingly soluble in water, its behavior in organic solvents can vary greatly based on conditions. Knowing its solubility is important for various industrial and biological applications!

Interesting facts

Interesting Facts about 2,2-Dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide

2,2-Dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide, a compound in the class of acetamides, brings together multiple functional groups that contribute to its intriguing properties and applications. Here are some fascinating aspects of this compound:

  • Pharmaceutical Applications: This compound may serve as a precursor in pharmaceutical synthesis or may exhibit biological activity that is valuable in medicinal chemistry.
  • Chlorine Substitution: The presence of chlorine atoms is notable. Chlorinated compounds often show enhanced lipophilicity, which can affect their bioavailability and toxicity.
  • Hydroxyl Group: The 4-hydroxy group plays a significant role in determining the compound's reactivity, making it a potential candidate for various biochemical interactions.
  • Structure Activity Relationship (SAR): Understanding how modifications in the structure, such as the substitution of methyl or chlorine groups, affect the biological activity can lead to the development of more effective derivatives.
  • Research Interest: Compounds like this offer opportunities for research in the fields of agrochemicals and materials science due to their diverse chemical reactivity.

As a *scientist*, investigating compounds like 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-acetamide can unveil novel insights into organic synthesis and pharmacology. Its complex interactions and transformations could yield important advancements in drug formulation and development. The study of such compounds is a reminder of the profound impact that even small alterations in molecular structure can have on chemical properties and potential applications.


Synonyms
Diloxanide
579-38-4
2,2-Dichloro-N-(4-hydroxyphenyl)-N-methylacetamide
Amebamida
Diloxanid
Entamide
Ame-boots
Diloxanida
Diloxanidum [INN-Latin]
Diloxanidum
RD 3803
Diloxanida [INN-Spanish]
Acetamide, 2,2-dichloro-N-(4-hydroxyphenyl)-N-methyl-
Diloxanide [INN:BAN:DCF]
2,2-Dichloro-4'-hydroxy-N-methylacetanilide
M & B 4453
EINECS 209-439-4
Diloxanide (INN)
UNII-89134SCM7M
BRN 2840273
89134SCM7M
DILOXANIDE [MI]
DILOXANIDE [INN]
DILOXANIDE [WHO-DD]
ACETANILIDE, 2,2-DICHLORO-4'-HYDROXY-N-METHYL-
2,2-Dichlor-4'-hydroxy-N-methylacetanilid
DTXSID0022939
2,2-Dichlor-4'-hydroxy-N-methylacetanilid [IUPAC]
Diloxanidum (INN-Latin)
Diloxanida (INN-Spanish)
2,2-Dichlor-4'-hydroxy-N-methylacetanilid (IUPAC)
DTXCID502939
P01AC01
209-439-4
gzzzsoogqloeob-uhfffaoysa-n
Diloxamide
SCHEMBL330136
CHEMBL2103768
AAA57938
BCP34404
AKOS028110538
DB08792
MS-23348
HY-119972
CS-0078852
NS00033813
D07844
EN300-254984
F82317
RD 3803; RD-3803; RD3803; Diloxanid
Z1269148170