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Quinuclidine

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Identification
Molecular formula
C7H13N
CAS number
100-76-5
IUPAC name
2,2-dimethyl-2-azoniabicyclo[2.2.1]heptane
State
State

At room temperature, quinuclidine exists as a solid. It is stable under ordinary conditions but should be stored in a dry, well-ventilated area away from incompatible substances.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.20
Boiling point (Celsius)
148.00
Boiling point (Kelvin)
421.20
General information
Molecular weight
111.19g/mol
Molar mass
111.1930g/mol
Density
0.8976g/cm3
Appearence

Quinuclidine is a colorless, crystalline solid. It often appears as a white powder when processed for chemical use.

Comment on solubility

Solubility of 2,2-Dimethyl-2-azoniabicyclo[2.2.1]heptane

2,2-Dimethyl-2-azoniabicyclo[2.2.1]heptane, often referred to as a quaternary ammonium compound, demonstrates distinctive solubility characteristics that are important for its applications in various fields. Here are some essential points to consider:

  • Polar Nature: The presence of the nitrogen atom in the azoniabicyclo structure introduces a significant degree of polarity, which enhances solubility in polar solvents such as water.
  • Alkyl Groups: The two methyl groups contribute to hydrophobic interactions, which may limit solubility in non-polar solvents while promoting solubility in polar environments.
  • Temperature Dependency: Solubility can vary with temperature, often increasing in polar solvents as temperature rises, which can affect the compound's utility in different chemical processes.
  • Ion Formation: As a quaternary ammonium compound, it exists primarily as a salt in aqueous solutions, which enhances its ionic interactions and overall solubility.

In conclusion, while 2,2-dimethyl-2-azoniabicyclo[2.2.1]heptane is soluble in water and other polar solvents due to its ionic nature, it may face limitations in non-polar mediums. Understanding these solubility properties is crucial for effectively utilizing this compound in industrial applications.

Interesting facts

Interesting Facts about 2,2-Dimethyl-2-azoniabicyclo[2.2.1]heptane

2,2-Dimethyl-2-azoniabicyclo[2.2.1]heptane, commonly referred to in scientific contexts as the quaternary ammonium compound, is a fascinating molecule with a rich tapestry of applications and characteristics. Here are some compelling aspects:

  • Structural Uniqueness: This compound is notable for its bicyclic structure which consists of a nitrogen atom that carries a positive charge. The bicyclo[2.2.1] design denotes the two bridged cycles that contribute to its unique chemical properties.
  • Reactivity: As a quaternary ammonium compound, it is often involved in ionic interactions, making it important in synthesis reactions and as a catalyst in various chemical processes.
  • Biological Significance: Compounds like this one are often studied for their roles in biological systems, particularly in neurotransmission. The positive charge on the nitrogen enables interactions with anionic centers in biological molecules.
  • Applications: This class of compound is utilized in various applications including:
    • Synthesis of complex organic molecules
    • Innovative drug design and development
    • Antimicrobial agents
  • Physical Properties: Its unique bicyclic structure contributes to its physical properties that differ markedly from typical aliphatic quaternary ammonium compounds. Such differences can have significant implications for its solubility and reactivity in various environments.
  • Research Potential: There is ongoing research into how variations in the structure of such azabicyclic compounds can lead to different biological activities, paving the way for advancements in medicinal chemistry and pharmacology.

As the fields of organic and medicinal chemistry continue to evolve, compounds like 2,2-dimethyl-2-azoniabicyclo[2.2.1]heptane remain at the forefront of scientific inquiry. Scientists are constantly exploring their potential, making discoveries that could lead to innovative applications in healthcare and beyond.

Synonyms
SCHEMBL25996571