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Pivalamide

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Identification
Molecular formula
C5H11NO
CAS number
759-46-0
IUPAC name
2,2-dimethylpropanamide
State
State

At room temperature, Pivalamide is in a solid state. It is stable under normal conditions and requires proper storage to avoid moisture uptake.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
101.17g/mol
Molar mass
101.1730g/mol
Density
0.9010g/cm3
Appearence

Pivalamide is typically a white crystalline solid. Its crystalline form appears as fine or translucent needles depending on the purity and crystallization method.

Comment on solubility

Solubility of 2,2-Dimethylpropanamide

2,2-dimethylpropanamide, also known as neopentylacetamide, exhibits a notable solubility profile which is crucial for its applications in various fields. The solubility of this compound can be assessed through the following key points:

  • Polarity: Due to the presence of a carbonyl group (C=O) in its amide functional group, 2,2-dimethylpropanamide is a polar molecule. This polarity enhances its solubility in polar solvents.
  • Solvent Compatibility: 2,2-dimethylpropanamide is soluble in water to a moderate extent, making it useful in aqueous environments. It can also dissolve in organic solvents such as ethanol and acetone.
  • Temperature Influence: The solubility may increase with temperature, as most solids dissolve better in warmer solvents. Thus, heating the solvent may facilitate greater solubility of the compound.

Chemists often say that "like dissolves like," and in the case of 2,2-dimethylpropanamide, its structure supports solubility in various environments, showcasing its versatility for chemical reactions and applications.

Overall, understanding the solubility characteristics of 2,2-dimethylpropanamide is essential for effectively utilizing this compound in both laboratory and industrial settings.

Interesting facts

Exploring 2,2-Dimethylpropanamide

2,2-Dimethylpropanamide is a fascinating compound in the realm of organic chemistry, primarily due to its structural characteristics and reactivity. This amide features a branched chain structure, derived from the straightforward molecule propanoic acid. Below are several intriguing aspects about this chemical:

  • Structural Complexity: The presence of two methyl groups attached to the second carbon makes it a branched amide, which can influence its physical and chemical properties compared to its straight-chain counterparts.
  • Amide Group: Being an amide, its derivatives play a crucial role in forming proteins and peptides. The amide bond (C=O and C-N) is particularly significant in biochemistry.
  • Applications: This compound has potential applications in the synthesis of pharmaceuticals and agrochemicals. Its unique structure may provide specific features desirable in drug design.
  • Reactivity: 2,2-Dimethylpropanamide can undergo various reactions including hydrolysis and substitution. This makes it a versatile component in organic synthesis.
  • Chemical Behavior: The electron-donating nature of the branched alkyl groups might influence the reactivity of this compound, making it an interesting subject for experimental studies.

In summary, 2,2-dimethylpropanamide stands out not only due to its unique structure but also because of its relevance in synthetic chemistry. As scientists continue to explore its properties and potential applications, this compound exemplifies the vast possibilities that organic chemistry presents.

Synonyms
Pivalamide
754-10-9
TRIMETHYLACETAMIDE
2,2-dimethylpropanamide
2,2-Dimethylpropionamide
Propanamide, 2,2-dimethyl-
2,2-Dimethyl-propionamide
pivalic acid amide
neopentanamide
FES86MR7ZI
EINECS 212-043-4
NSC 17584
NSC-17584
alpha,alpha-dimethylpropionamide
DTXSID6061072
XIPFMBOWZXULIA-UHFFFAOYSA-
.ALPHA.,.ALPHA.-DIMETHYLPROPIONAMIDE
DTXCID7047778
212-043-4
inchi=1/c5h11no/c1-5(2,3)4(6)7/h1-3h3,(h2,6,7)
2,2,2-Trimethylacetamide
MFCD00008011
Propanamide,2,2-dimethyl-
trimethylacetarnide
trimethyl acetamide
NSC17584
TAY
Trimethylacetamide, 98%
UNII-FES86MR7ZI
SCHEMBL2484
CHEMBL345235
propane, 2-carbamoyl-2-methyl-
HMS1763O22
AC2528
BDBM50226158
AKOS000282747
CS-W021470
FD03410
PB47992
DS-10181
SY037452
DB-055956
NS00037708
P0819
EN300-49244
AC-907/25014088
Q7199623
Z56895677