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Cefditoren pivoxil

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Identification
Molecular formula
C25H28N6O7S3
CAS number
117467-28-4
IUPAC name
2,2-dimethylpropanoyloxymethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(5-methyltetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
State
State

At room temperature, Cefditoren pivoxil is typically a solid. It is a crystalline powder which means it retains its solid state at standard conditions.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
668.76g/mol
Molar mass
668.7550g/mol
Density
1.4400g/cm3
Appearence

Cefditoren pivoxil appears as a white to off-white crystalline powder. Its appearance can be refined more under different conditions where it can appear slightly yellowish.

Comment on solubility

Solubility of 2,2-dimethylpropanoyloxymethyl 7-[[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(5-methyltetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

This compound, with the chemical formula C25H28N6O7S3, displays intriguing solubility characteristics that are often vital for its application in various chemical and pharmaceutical processes. Understanding its solubility can help in various experiments and formulations.

Key Points on Solubility:

  • Hydrophilicity vs. Hydrophobicity: The balance between its hydrophilic and hydrophobic regions influences its solubility in water and organic solvents.
  • Temperature Dependency: As is common with many compounds, solubility may increase with temperature. This is crucial during dissolution processes.
  • pH Sensitivity: Given the presence of functional groups, the solubility could vary with changes in pH, affecting ionization and solubility dynamics significantly.
  • Interactions: Interactions with solvents, like hydrogen bonding and van der Waals forces, play essential roles in determining the solubility characteristics.
  • Saturation Limits: It's important to determine the saturation limits of this compound in various solvents to ensure effective concentration for the desired applications.

In conclusion, the solubility of this complex compound is not a straightforward attribute; rather, it is governed by multiple factors that must be considered for optimal usage.

Interesting facts

Interesting Facts about 2,2-Dimethylpropanoyloxymethyl 7-[[2-(2-Aminothiazol-4-yl)-2-Methoxyimino-Acetyl]amino]-3-[(5-Methyltetrazol-2-yl)methyl]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]oct-2-ene-2-Carboxylate

This compound, with its complex structure, showcases the fascinating world of medicinal chemistry. Here are some intriguing aspects:

  • Mechanism of Action: This compound is part of a novel class of antibiotics, which work by inhibiting bacterial cell wall synthesis. Its unique structure allows it to target specific pathogens more effectively.
  • Bioactivity: The incorporation of thiazole and tetrazole rings is significant because these motifs often exhibit enhanced bioactivity, aiding in the overall efficacy of therapeutic agents.
  • Analog Development: Chemists often synthesize analogs of this compound to enhance their pharmacological profiles. *This iterative process is crucial for drug development, leading to improved selectivity and lower side effects.*
  • Structure-Activity Relationship (SAR): Researchers study the relationship between the chemical structure and its biological activity, which serves as a pathway to design even more potent compounds.
  • Synthesis Challenges: The synthesis of this compound entails multiple steps requiring precision and expertise. *Overcoming these challenges represents a significant achievement in organic synthesis.*
  • Potential Applications: Beyond antibiotics, there is potential for this compound or its derivatives to be explored in anti-cancer therapies due to similar mechanisms observed in camptothecin and other anti-cancer drugs.

In summary, this compound is not just a chemical entity; it embodies the fusion of structure, function, and a promising future in biomedical applications. *As scientists continue to unravel its potential, the excitement in the lab is palpable.*

Synonyms
cefteram pivoxil
82547-81-7
2,2-dimethylpropanoyloxymethyl 7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(5-methyltetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Ro 19-5248; T 2588; Tomiron; Tomiron 100
BCP13775
Ro 19-5248;Ro-19-5248;T 2588;T-2588
{7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(5-methyl-1,2,3,4-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carbonyloxy}methyl 2,2-dimethylpropanoate