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Furazolidone

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Identification
Molecular formula
C8H7N3O5
CAS number
67-45-8
IUPAC name
2,2-dimethylpropyl 3-[(5-nitro-2-furyl)methyleneamino]-2,5-dioxo-imidazolidine-1-carboxylate
State
State

Furazolidone is typically found as a solid at room temperature. It can be handled as a powder and stored easily when kept dry.

Melting point (Celsius)
270.00
Melting point (Kelvin)
543.00
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
225.16g/mol
Molar mass
225.1570g/mol
Density
1.4370g/cm3
Appearence

Furazolidone is a yellow, crystalline powder. It may have a slight odor and is generally stable under normal conditions of use and storage. It is sparingly soluble in water, leading to a suspension when mixed.

Comment on solubility

Solubility of 2,2-Dimethylpropyl 3-[(5-Nitro-2-Furyl)methyleneamino]-2,5-dioxo-imidazolidine-1-carboxylate

The solubility of 2,2-dimethylpropyl 3-[(5-nitro-2-furyl)methyleneamino]-2,5-dioxo-imidazolidine-1-carboxylate can be quite intricate due to its complex structure and the presence of various functional groups. Understanding its solubility is crucial for applications in pharmaceuticals and other industries. Here are some factors that influence its solubility:

  • Polarity: The presence of polar functional groups, such as carboxylate, may increase its solubility in polar solvents.
  • Hydrogen Bonding: Interactions through hydrogen bonding can significantly affect solubility, enhancing the dissolution in aqueous environments.
  • Solvent Environment: Solubility can vary widely depending on the solvent used, with water being the most common solvent.
  • Temperature: As with many compounds, increasing temperature often facilitates higher solubility rates.

Generally, compounds with complex aromatic structures and nitro groups may show limited solubility in non-polar solvents, while exhibiting improved solubility in polar solvents. As the old saying goes, “Like dissolves like,” which is a simple way to remember that similar polarities enhance solubility. Therefore, for practical applications, suitable solvent choices and conditions should be thoroughly investigated to optimize solubility.

Interesting facts

Interesting Facts about 2,2-Dimethylpropyl 3-[(5-Nitro-2-furyl)methyleneamino]-2,5-dioxo-imidazolidine-1-carboxylate

This fascinating compound belongs to the class of imidazolidines, which are notable for their diverse biological activities. Here are some engaging points to consider:

  • Structural Complexity: The incorporation of a nitro-2-furyl group introduces unique properties, allowing for interactions that may enhance its pharmacological profiles.
  • Biological Activity: Compounds featuring furan and nitrogen functionalities are often subjected to extensive research due to their potential in medicinal chemistry. They may exhibit antimicrobial, anti-inflammatory, or antitumor properties.
  • Versatile Applications: Beyond medicinal uses, this compound might have implications in fields such as agrochemistry, where it could serve as a pesticide or herbicide, given the right modifications.
  • Research Potential: The unique combination of dimethylpropyl and imidazolidine systems opens avenues for the synthesis of derivatives, which could lead to discoveries of new compounds with enhanced efficacy.
  • Imidazolidine Chemistry: The core imidazolidine structure is not only stable but also a key building block for more complex molecular architectures. This form of nitrogen heterocycle has sparked interest in various domains including materials science and organic electronics.

As chemists continue to explore the potential of this compound, they are reminded of the importance of interdisciplinary approaches, integrating aspects from both organic synthesis and biological assessment to unlock new possibilities.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Every exploration of compounds like this one enriches our understanding and fuels innovation.