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Lidocaine

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Identification
Molecular formula
C14H22ClN2O
CAS number
137-58-6
IUPAC name
2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine
State
State

Lidocaine is most commonly found in the solid state as a crystalline powder at room temperature. It is widely used in medical settings in various formulations including injectable solutions, topical creams, and gels.

Melting point (Celsius)
68.50
Melting point (Kelvin)
341.65
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0000g/cm3
Appearence

Lidocaine typically appears as a white crystalline powder that is odorless. It can also appear as a transparent or white gel when formulated for topical use. Its powder form is generally free-flowing and readily soluble in water and alcohol.

Comment on solubility

Solubility of 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine

The solubility of 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine can be influenced by several factors, including its molecular structure and polarity. Understanding these factors is crucial for predicting its behavior in various solvents. Here are some important points to consider:

  • Polarity: The presence of the trichloro group may enhance the polarity of the compound, potentially leading to better solubility in polar solvents, such as water, albeit its chlorinated nature might also introduce competing hydrophobic characteristics.
  • Hydrophobic Interactions: The phenyl ring and ethyl groups may confer hydrophobic properties, making the compound less soluble in highly polar solvents.
  • Solvent Compatibility: This compound is likely to have greater solubility in organic solvents like chloroform, ethanol, or acetone due to their common non-polar characteristics aligning with the hydrophobic portions of the molecule.
  • Temperature Influence: As with many chemical compounds, solubility can increase with temperature, which could enhance the dissolution of this compound in appropriate solvents.

In summary, while 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine may exhibit varying solubilities depending on the solvent used, it is generally expected to show more compatibility with organic solvents due to its structural components. Understanding these solubility trends is vital for effective applications in chemical processes.

Interesting facts

Exploring 2,2,2-Trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine

This intriguing compound, known as 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine, presents a fascinating blend of chemical structure and potential applications. Here are some captivating facts about this unique chemical:

  • Chlorinated Compounds: The presence of three chlorine atoms in its structure indicates that it belongs to the class of chlorinated compounds, which are widely studied for their reactivity and properties. Chlorine atoms can significantly alter the physical and chemical characteristics of a compound.
  • Behavior in Biological Systems: This compound has potential relevance in biological applications, particularly in areas such as drug discovery and development. The presence of both an amine and a chlorinated derivative often signals interesting pharmacological activities.
  • Versatile Use: Chlorinated ethanamines have been explored as intermediates in organic synthesis, including the manufacture of agrochemicals and pharmaceuticals. Their unique reactivity can lead to the discovery of novel compounds.
  • Potential Environmental Impact: As with many chlorine-containing compounds, there are concerns over the environmental impact and toxicity. Their stability and persistence can make them potential pollutants, leading to ongoing research in green chemistry for safer alternatives.
  • Chemical Relationships: Understanding the structure of 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine enlightens chemists on how modifications to the molecular structure can impact activity and stability, a critical aspect of medicinal chemistry.

In summary, 2,2,2-trichloro-N-(1-methyl-2-phenyl-ethyl)ethanimine is more than just a compound; it embodies a blend of fascinating properties that have implications across multiple scientific disciplines. As researchers continue to delve into its characteristics, the compound could hold the key to new discoveries in chemical research and application.

Synonyms
5581-35-1
alpha-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine
Amfecloral
AMPHECLORAL
Anfecloral
(+)-Amfecloral
(-)-Amfecloral
Amphecloral [USAN]
Amfecloral, (+)-
Amfecloral, (-)-
Amfecloral [INN]
S0DYI19OEX
WZS9L0Z92R
6015XOA0BI
alpha-Methyl-N-(2,2,2-trichloroethylidene)phenethylamine
Amfecloral (INN)
Amphecloral (USAN)
25394-63-2
71528-69-3
Amphechloral
UNII-S0DYI19OEX
UNII-WZS9L0Z92R
2,2,2-trichloro-N-(1-phenylpropan-2-yl)ethanimine
UNII-6015XOA0BI
Acutran; Amphecloral; alpha-Methyl-N-(2,2,2-trichloroethylidene)phenethylamine
(+)-Amphecloral
(-)-Amphecloral
AMPHECLORAL [MI]
SCHEMBL119094
1-Phenyl-N-(2,2,2-trichlorethyliden)-2-propylamin
CHEMBL2105544
DTXSID00863571
CHEBI:135924
Benzeneethanamine, .alpha.-methyl-N-(2,2,2-trichloroethylidene)-
Benzeneethanamine, alpha-methyl-N-(2,2,2-trichloroethylidene)-, (+)-
Benzeneethanamine, alpha-methyl-N-(2,2,2-trichloroethylidene)-, (-)-
DB08924
D02926
Q4745975
alpha-Methyl-N-(2,2,2-trichloroethylidene)-benzeneethanamine
Benzeneethanamine, alpha-methyl-N-(2,2,2-trichloroethylidene)-
Acutran; Amphecloral; -Methyl-N-(2,2,2-trichloroethylidene)phenethylamine
BENZENEETHANAMINE, .ALPHA.-METHYL-N-(2,2,2-TRICHLOROETHYLIDENE)-, (+)-
BENZENEETHANAMINE, .ALPHA.-METHYL-N-(2,2,2-TRICHLOROETHYLIDENE)-, (-)-