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2,2,2-Trichloroethanol

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Identification
Molecular formula
C2H3Cl3O
CAS number
115-20-8
IUPAC name
2,2,2-trichloroethanol
State
State

At room temperature, 2,2,2-trichloroethanol is in a liquid state.

Melting point (Celsius)
9.00
Melting point (Kelvin)
282.15
Boiling point (Celsius)
151.00
Boiling point (Kelvin)
424.15
General information
Molecular weight
149.44g/mol
Molar mass
149.4380g/mol
Density
1.5830g/cm3
Appearence

2,2,2-Trichloroethanol appears as a colorless liquid. It typically has a pungent odor. Due to its hydrogen bonding ability, it is often used as a precursor in various organic synthesis processes.

Comment on solubility

Solubility of 2,2,2-Trichloroethanol

2,2,2-Trichloroethanol (C2HCl3O) exhibits notable solubility characteristics that are important to consider in various applications. This organic compound is known for its moderate solubility in water, displaying a *log P* value indicating that it is more hydrophilic than its hydrophobic counterparts.

Key Points on Solubility:

  • Water Solubility: 2,2,2-Trichloroethanol is soluble in water due to its ability to form hydrogen bonds, despite the presence of multiple chlorine atoms which increase its polar nature.
  • Solvent Solubility: It is also soluble in many organic solvents, including ethanol and ether, making it versatile in various chemical reactions and formulations.
  • Factors Affecting Solubility: The solubility in water can be influenced by temperature and pH levels, with increased temperatures generally enhancing solubility.
  • Applications: Its solubility properties are instrumental in applications such as pharmaceuticals and chemical synthesis, where dissolving the compound effectively can be crucial.

In summary, the solubility of 2,2,2-trichloroethanol is a blend of its polar hydroxyl group and the three electronegative chlorine atoms, making it a fascinating compound for both practical and theoretical studies.

Interesting facts

Interesting Facts about 2,2,2-Trichloroethanol

2,2,2-Trichloroethanol is a fascinating compound that boasts a range of intriguing characteristics and applications in the field of chemistry. Here are some key points that highlight its significance:

  • Chemical Structure: As indicated by its name, this compound consists of three chlorine atoms attached to a central carbon atom, making it a chlorinated alcohol. Its structure leads to various chemical properties that distinguish it from unchlorinated alcohols.
  • Historical Use: This compound was once used extensively as a solvent and in the manufacturing of other chemicals. Its development during the mid-20th century was significant in the world of organic chemistry.
  • Biological Relevance: 2,2,2-trichloroethanol is often studied in the context of pharmacology. It has been used to investigate the metabolic pathways of various anesthetics and other pharmaceutical agents due to its unique biochemical interactions.
  • Toxicity Considerations: While the compound has valuable applications, it is also crucial to handle it with care. Awareness of its toxicological properties is essential for the safety of researchers and industrial workers alike.
  • Environmental Impact: There is ongoing research regarding the environmental effects of chlorinated compounds, including 2,2,2-trichloroethanol, which can raise concerns about their persistence and bioaccumulation in ecosystems.

Overall, 2,2,2-trichloroethanol serves as a compelling example of how a simple alteration in chemical structure can lead to profound changes in properties and applications. As noted by chemists, “Understanding the nuances of chlorinated compounds can unlock new possibilities in both synthesis and application.”

Synonyms
2,2,2-TRICHLOROETHANOL
115-20-8
Trichloroethanol
Trichlorethanol
Trichloroethyl alcohol
Ethanol, 2,2,2-trichloro-
2,2,2-Trichloroethan-1-ol
2,2,2-Trichloro-1-ethanol
(Hydroxymethyl)trichloromethane
2,2,2-Trichloroethyl alcohol
2,2,2-trichloro-ethanol
beta-trichloroethanol
NSC 66407
CCl3CH2OH
CCRIS 6763
EINECS 204-071-0
UNII-AW835AJ62N
BRN 1697495
AW835AJ62N
CHEBI:28094
NSC-66407
.beta.,.beta.,.beta-Trichloroethanol
2, 2,2-Trichloroethanol
2,2,2-tris-chloroethanol
beta,beta,.beta-Trichloroethanol
DTXSID1021950
ETHANOL,2,2,2-TRICHLORO
NSC66407
2,2,2-TRICHLOROETHANOL [MI]
2,2,2-TRICHLOROETHANOL [WHO-DD]
2,2,2-Trichloroethanol (ACD/Name 4.0)
4yas
MFCD00004677
2,2-Trichloroethanol
.beta.-Trichloroethanol
2,2,2-trichloroethanoI
2,2,2Trichloro1ethanol
WLN: Q1XGGG
2,2,2-trichloro ethanol
2,2-Trichloro-1-ethanol
Ethanol, 2,2,2trichloro
2,2-Trichloroethyl alcohol
SCHEMBL1027
CHEMBL1171
2,2,2Trichloroethyl alcohol
beta,beta,betaTrichloroethanol
2,2,2-Trichloroethanol purum
DTXCID401950
GTPL2293
BCP32905
HY-B1500
STR02056
AKOS016010272
Trichloroethanol;Trichloroethyl alcohol
FT159699
CS-0013285
NS00023730
T0622
C07490
D70779
EN300-120004
2,2,2-Trichloroethanol, ReagentPlus(R), >=99%
2,2,2-Trichloroethanol, purum, >=98.0% (GC)
Q4596742
2,2,2-Trichloroethanol, Vetec(TM) reagent grade, 98%
204-071-0
8FH