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Trifludimoxazin

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Identification
Molecular formula
C17H10F6N2O2
CAS number
1258831-68-3
IUPAC name
2,2,2-trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide
State
State

At room temperature, Trifludimoxazin is in a solid state, appearing as a white to off-white powder.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
542.00
Boiling point (Kelvin)
815.15
General information
Molecular weight
393.27g/mol
Molar mass
393.2710g/mol
Density
1.5747g/cm3
Appearence

Trifludimoxazin is a solid compound that appears as a crystalline powder. This powder is typically white to off-white in color, indicating its purity and composition.

Comment on solubility

Solubility of 2,2,2-Trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide

2,2,2-Trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide possesses unique solubility characteristics, primarily influenced by its chemical structure. The presence of multiple trifluoro groups contributes to its hydrophobic nature, which significantly affects its interaction with solvents.

Solubility Characteristics:

  • In Water: The compound is generally expected to have low solubility in water due to the predominance of fluorinated groups that inhibit hydrogen bonding.
  • In Organic Solvents: It may exhibit better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or acetone, owing to their non-polar characteristics that align with the compound's hydrophobic regions.
  • Impact of Temperature: The solubility may increase with temperature, as increased kinetic energy can facilitate the dissolution process even for compounds resistant to solvation.

Overall, while 2,2,2-trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide displays limited solubility in aqueous solutions, its compatibility with various organic solvents opens avenues for diverse applications in chemical processes. Remember, as the saying goes, "like dissolves like," and understanding this principle is key to predicting the behavior of complex compounds like this one.

Interesting facts

Interesting Facts about 2,2,2-Trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide

This intriguing compound is a member of the fluorenyl amide class and features several unique structural components that have garnered interest in the field of medicinal chemistry. Here are some noteworthy aspects:

  • Fluorine's Role: The presence of fluorine in its structure, specifically in the form of 2,2,2-trifluoro groups, significantly influences the compound's reactivity and stability. Fluorinated compounds often exhibit enhanced lipophilicity and metabolic resistance.
  • Potential Applications: Due to its unique chemical properties, this compound has the potential for use in pharmaceuticals, particularly in the development of new therapeutic agents targeting various diseases.
  • Structure-Activity Relationship (SAR): The modification of fluorine atoms can play a critical role in understanding the SAR, influencing how the compound interacts with biological targets.
  • Intriguing Synthesis: The synthesis of this compound could involve complex multi-step reactions, illustrating the creativity and precision required in organic chemistry to design compounds with specific applications.
  • Research Interest: Given its unique structure, researchers may be particularly interested in studying its biochemical properties and potential applications in drug design—prompting a deeper exploration into the mechanisms of action and efficacy.

In summary, the multifaceted nature of 2,2,2-trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide demonstrates the fascinating interplay between chemistry and medicinal applications. Its complexity invites scientists to delve into further studies, possibly leading to novel discoveries in drug development.

Synonyms
BRN 3498707
ACETAMIDE, N,N'-FLUOREN-2,7-YLENEBIS(TRIFLUORO-
391-57-1
N,N'-Fluoren-2,7-ylenebis(trifluoroacetamide)
DTXSID70192345
4-13-00-00451 (Beilstein Handbook Reference)
N,N'-9H-fluorene-2,7-diylbis(2,2,2-trifluoroacetamide)
DTXCID80114836
2,7-bis-Trifluoracetylaminofluoren
STK292557
AKOS003335468
2,2,2-trifluoro-N-[7-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]acetamide