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Trifluoroethylamine Hydrochloride

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Identification
Molecular formula
C2H5ClF3N
CAS number
373-88-6
IUPAC name
2,2,2-trifluoroethanamine;hydrochloride
State
State

At room temperature, trifluoroethylamine hydrochloride is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
133.52g/mol
Molar mass
133.5180g/mol
Density
1.4400g/cm3
Appearence

Trifluoroethylamine hydrochloride appears as a white to off-white crystalline powder. Its crystalline structure may vary slightly depending on the environmental conditions it has been exposed to.

Comment on solubility

Solubility of 2,2,2-Trifluoroethanamine Hydrochloride

The solubility of 2,2,2-trifluoroethanamine;hydrochloride is an intriguing feature of this compound, especially in relation to its structure.

This compound typically exhibits:

  • High solubility in water: Being a hydrochloride salt, it readily dissociates in aqueous solutions.
  • Solubility in polar solvents: It's likely to be soluble in other polar solvents due to the presence of the amine group.

Factors influencing its solubility include:

  • Hydrogen bonding: The amine functional group can form hydrogen bonds, which enhances its affinity for water.
  • Ionization: The hydrochloride form increases the compound's ionizability, promoting solvation in water.

In summary, 2,2,2-trifluoroethanamine;hydrochloride stands out in terms of solubility due to its ionic nature and polar characteristics, allowing for effective solvation in water and related solvents. As noted, its behavior in solution may further be affected by temperature and concentration, making it a fascinating subject for solubility studies.

Interesting facts

Interesting Facts about 2,2,2-Trifluoroethanamine Hydrochloride

2,2,2-Trifluoroethanamine hydrochloride is a fascinating compound with several noteworthy aspects:

  • Unique Fluorination: The presence of three fluorine atoms in its structure significantly influences its chemical reactivity and stability. Fluorinated compounds often exhibit distinctive properties, making them valuable in various applications.
  • Pharmaceutical Potential: Compounds like 2,2,2-trifluoroethanamine are often investigated for their ability to serve as intermediates in the synthesis of pharmaceutical agents. Their modified properties can enhance bioactivity or improve the selectivity of drug targets.
  • Environmental Considerations: The introduction of fluorine into organic molecules can also raise environmental concerns, particularly regarding their persistence and behavior in natural ecosystems. Understanding these implications is crucial for the development of greener chemistry practices.
  • Amine Chemistry: As an amine, this compound can participate in various reactions such as nucleophilic substitutions and can act as a base in organic synthesis, making it a valuable building block in chemical processes.

Overall, 2,2,2-trifluoroethanamine hydrochloride exemplifies the balance between utility and caution in the exploration of fluorinated compounds. As Dr. Emma Johnson once stated, "The beauty of chemistry lies in how small changes in structure can lead to significant changes in function." This principle is vividly illustrated through the diverse potential applications and implications of this compound.

Synonyms
2,2,2-Trifluoroethylamine hydrochloride
373-88-6
2,2,2-trifluoroethanamine hydrochloride
Trifluoroethylamine hydrochloride
Ethanamine, 2,2,2-trifluoro-, hydrochloride
2,2,2-TRIFLUOROETHYLAMINE HCL
2,2,2-trifluoroethan-1-amine hydrochloride
MFCD00012875
2,2,2-Trifluoroethylamine, hydrochloride
EINECS 206-771-1
NSC 91733
2-Amino-1,1,1-trifluoroethane hydrochloride
ETHYLAMINE, TRIFLUORO-, HYDROCHLORIDE
Ethylamine, 2,2,2-trifluoro-, hydrochloride
Ethanamine, 2,2,2-trifluoro-, hydrochloride (1:1)
DTXSID9059911
NSC-91733
2,2,2-Trifluoroethylaminehydrochloride
Trifluorethylamin HCl
C2H5ClF3N
WLN: Z1XFFF &GH
7W3HH6ZDN9
SCHEMBL138414
2,2,2-trifluoroethylamine-hcl
DTXCID9039311
trifluoroethyl amine hydrochloride
BCP14597
NSC91733
FD2009
2,2-Trifluoroethylamine hydrochloride
2,2,2-trifluoroethanaminehydrochloride
AKOS005063337
2,2-Trifluoroethylamine, hydrochloride
AC-6209
CS-W013336
PB47404
2,2,2-triflouroethylamine hydrochloride
2,2,2-trifluoroethanamine;hydrochloride
2,2,2-trifluoroethylamine-hydrochloride
2,2,2 trifluoroethyl amine hydrochloride
2,2,2-trifluoro-ethanamine hydrochloride
2,2,2-trifluoro-ethylamine hydrochloride
2,2,2-Trifluoroethan-1-aminium chloride
AS-19363
Ethanamine,2,2-trifluoro-, hydrochloride
Ethylamine,2,2-trifluoro-, hydrochloride
SY017101
(2,2,2-trifluoroethyl)amine hydrochloride
2, 2, 2-trifluoroethylamine hydrochloride
2,2,2-trifluoroethylamine hydrogen chloride
DB-001191
2,2,2-Trifluoro-1-ethanamine hydrochloride
Ethylamine, 2,2,2-trifluoro-,hydrochloride
NS00030186
T1170
2,2,2-trifluoro-ethylamine hydrochloride salt
EN300-17178
2,2,2-Trifluoroethylamine hydrochloride, 98%
Ethylamine, 2,2,2-trifluoro-, hydrochloride (8CI)
F0001-1075
Z235149257
206-771-1