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2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate

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Identification
Molecular formula
C7H10F3NO2
CAS number
82461-66-1
IUPAC name
2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate
State
State

This compound is primarily found as a liquid at room temperature.

Melting point (Celsius)
-93.00
Melting point (Kelvin)
180.15
Boiling point (Celsius)
62.00
Boiling point (Kelvin)
335.15
General information
Molecular weight
195.16g/mol
Molar mass
195.1630g/mol
Density
1.3330g/cm3
Appearence

The compound is typically a colorless liquid. It may appear transparent and without any solid impurities when in pure form. However, detailed descriptions of appearance can vary depending on the presence of impurities or specific preparation methods.

Comment on solubility

Solubility of 2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate

The solubility of 2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate is influenced by its unique chemical structure, featuring both hydrophobic and hydrophilic characteristics. Understanding the solubility of this compound is crucial for its applications in various chemical processes.

Key Factors Influencing Solubility:

  • Polarity: The presence of the aziridine ring imparts some degree of polarity, which might enhance solubility in polar solvents.
  • Fluorine Atoms: The trifluoroethyl group is highly electronegative, which generally leads to decreased solubility in water but may increase solubility in organic solvents.
  • Functional Groups: The ester functional group in the propanoate part can interact favorably with solvents that have similar polar characteristics.

In practical terms, one can hypothesize that:

  • The compound may exhibit limited solubility in water.
  • It is likely to have a better solubility profile in organic solvents such as acetone, dichloromethane, or ethanol.

In conclusion, while 2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate is expected to be less soluble in aqueous environments, its overall solubility behavior in nonpolar or mildly polar solvents could be quite favorable, making it a compound of interest in various chemical applications. Further experimental data would provide valuable insights into its solubility characteristics.

Interesting facts

Interesting Facts about 2,2,2-Trifluoroethyl 3-(aziridin-1-yl)propanoate

2,2,2-Trifluoroethyl 3-(aziridin-1-yl)propanoate is a fascinating compound that stands out in the realm of organic chemistry due to its unique structure and properties. Below are some intriguing points about this substance:

Structural Characteristics

  • Fluorinated Component: The presence of trifluoroethyl groups in this compound significantly enhances its reactivity and stability, making it a valuable candidate for various chemical reactions.
  • Aziridine Ring: The aziridin-1-yl group introduces intriguing ring strain, contributing to the chemical’s high reactivity, particularly in nucleophilic attack scenarios.

Applications

  • This compound exhibits potential applications in pharmaceutical chemistry, particularly in the development of novel medications.
  • It can serve as an intermediate in the synthesis of more complex molecules due to its reactive aziridine component.

Reaction Mechanisms

The intriguing features of this compound lead to various reaction mechanisms, such as:

  • Ring-opening reactions: The strained aziridine can undergo ring-opening which can be exploited to create diverse derivatives.
  • Fluoroalkylation: The trifluoroethyl group allows for selective fluoroalkylation reactions, providing routes to compounds with enhanced biological activity.

Research Insights

Ongoing studies suggest that compounds like this one could lead to breakthroughs in the field of materials science and biochemistry, promoting further interest in fluorinated compounds and their functionalities.

As with many intriguing compounds, the synthesis, properties, and reactivity of 2,2,2-trifluoroethyl 3-(aziridin-1-yl)propanoate pose numerous opportunities for exploration, inviting chemists to delve deeper into its potential.

Synonyms
1-AZIRIDINEPROPIONIC ACID, 2,2,2-TRIFLUOROETHYL ESTER
Aziridine propionic acid, 2,2,2-trifluoroethyl ester
24116-17-4
1-Aziridinepropanoic acid, 2,2,2-trifluoroethyl ester
DTXSID80178837
RefChem:227739
DTXCID40101328