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2,2,2-trifluoroethyl-N-phenylcarbamate

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Identification
Molecular formula
C9H8F3NO2
CAS number
704-69-6
IUPAC name
2,2,2-trifluoroethyl N-phenylcarbamate
State
State

At room temperature, 2,2,2-trifluoroethyl N-phenylcarbamate is in a liquid state.

Melting point (Celsius)
-14.00
Melting point (Kelvin)
259.15
Boiling point (Celsius)
247.00
Boiling point (Kelvin)
520.15
General information
Molecular weight
219.17g/mol
Molar mass
219.1730g/mol
Density
1.2895g/cm3
Appearence

2,2,2-Trifluoroethyl N-phenylcarbamate is a colorless to pale yellow liquid.

Comment on solubility

Solubility of 2,2,2-trifluoroethyl N-phenylcarbamate

The solubility of 2,2,2-trifluoroethyl N-phenylcarbamate in various solvents is an intriguing aspect that influences its applications and behavior in chemical processes. This compound exhibits a unique solubility profile owing to the presence of both hydrophobic trifluoromethyl groups and a polar carbamate functional group.

Key Factors Influencing Solubility:

  • Polarity: The molecular structure contributes to varying interactions in polar vs. non-polar solvents.
  • Hydrophobic Interactions: The trifluoromethyl group enhances hydrophobic characteristics, which may reduce solubility in water but increase solubility in organic solvents.
  • Hydrogen Bonding: The carbamate moiety can engage in hydrogen bonding, particularly with protic solvents like alcohols, potentially enhancing solubility in such media.

In practice, it is essential to consider the compound's solubility in:

  1. Polar solvents (e.g., water, methanol)
  2. Non-polar solvents (e.g., hexane, toluene)
  3. Intermediate polarity solvents (e.g., acetone, acetonitrile)

Experimentation may reveal that 2,2,2-trifluoroethyl N-phenylcarbamate has moderate solubility in organic solvents, while its solubility in water is limited. As always, understanding the solubility characteristics of this compound is crucial for optimizing its use in various chemical applications.

Interesting facts

Exploring 2,2,2-Trifluoroethyl N-phenylcarbamate

2,2,2-Trifluoroethyl N-phenylcarbamate is a captivating compound that belongs to the class of carbamates, known for their versatility and far-reaching applications in various fields. Here are some fascinating insights about this unique compound:

  • Fluorinated Features: The presence of the trifluoroethyl group confers interesting properties to the molecule, making it hydrophobic and potentially useful in pharmaceutical applications.
  • Biological Relevance: Carbamates like this one often exhibit insecticidal and herbicidal properties, which can be leveraged in pest control and agriculture.
  • Synthesis Potential: The synthetic routes for creating carbamates can vary, but they often involve the reaction of amines with isocyanates, showcasing the intricate dance of organic chemistry.
  • Regulation and Safety: With emerging regulations around chemical compounds, understanding the safety profile of agents like 2,2,2-trifluoroethyl N-phenylcarbamate is crucial for responsible handling and usage.

As quoted by renowned chemists, “The true essence of innovation lies in understanding the properties and potential of the smallest molecules.” In the case of 2,2,2-trifluoroethyl N-phenylcarbamate, this statement rings especially true. By harnessing its properties, scientists can open up new avenues in medicinal chemistry, enhancing therapeutic efficacy and expanding the toolkit available for combating diseases.

Further research into this compound’s potential interactions and applications can pave the way for groundbreaking discoveries in the field of organic chemistry.

Synonyms
2,2,2-trifluoroethyl N-phenylcarbamate
370-32-1
2,2,2-trifluoroethyl phenylcarbamate
NSC202686
Enamine_001738
SCHEMBL4354147
DTXSID80958171
DWYDJEHECXADHP-UHFFFAOYSA-N
HMS1398O22
AAA37032
STK091568
2,2,2-trifluoroethylN-phenylcarbamate
AKOS001033010
NSC 202686
NSC-202686
CS-0235860
EN300-16343
2,2,2-Trifluoroethyl hydrogen phenylcarbonimidate
Z55292530
101-533-2