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2-(4-Methoxyphenyl)-3-(4-methoxyphenyl)-1H-indole

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Identification
Molecular formula
C23H19NO2
CAS number
91447-51-9
IUPAC name
2,3-bis(4-methoxyphenyl)-1H-indole
State
State

At room temperature, 2,3-bis(4-methoxyphenyl)-1H-indole is typically found as a solid. Its crystalline structure makes it relatively stable under standard conditions.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
496.00
Boiling point (Kelvin)
769.15
General information
Molecular weight
357.41g/mol
Molar mass
357.4090g/mol
Density
1.2200g/cm3
Appearence

This compound is a solid with a crystalline appearance. It may have a coloration ranging from white to off-white, depending on its purity. The solid is often found in a powdered or crystalline form.

Comment on solubility

Solubility of 2,3-bis(4-methoxyphenyl)-1H-indole

The solubility of 2,3-bis(4-methoxyphenyl)-1H-indole, a complex organic compound, presents unique characteristics that are influenced by its molecular structure. Understanding its solubility is crucial for various applications, particularly in pharmaceuticals and organic synthesis.

Key Factors Affecting Solubility:

  • Molecular Polarity: The presence of methoxy groups (-OCH3) enhances the compound's polar characteristics, which can facilitate solubility in polar solvents.
  • Structural Configuration: The indole base structure may interact differently with solvents, affecting overall solubility.
  • Temperature: As with many organic compounds, increased temperature typically improves solubility by providing more kinetic energy to overcome intermolecular forces.

Solvent Choices:

This compound tends to be soluble in organic solvents such as:

  • DMSO (dimethyl sulfoxide)
  • Dimethylformamide (DMF)
  • Acetone

However, it may show limited solubility in water due to hydrophobic characteristics associated with the indole ring.

In summary, the solubility of 2,3-bis(4-methoxyphenyl)-1H-indole is a multifaceted topic that integrates molecular structure, solvent interaction, and environmental conditions. Analyzing these factors not only elucidates its behavior in solution but also guides its practical applications.

Interesting facts

Interesting Facts About 2,3-bis(4-methoxyphenyl)-1H-indole

2,3-bis(4-methoxyphenyl)-1H-indole is a fascinating compound that showcases the beautiful complexity of organic chemistry. Here are some intriguing insights into this remarkable molecule:

  • Indole Framework: The compound is derived from the indole structure, which consists of a fused benzene and pyrrole ring. This heterocyclic structure is critical in the fields of pharmacology and biological chemistry.
  • Versatile Applications: Compounds based on the indole framework are often studied for their biological activities. The potential applications of 2,3-bis(4-methoxyphenyl)-1H-indole could include serving as precursors for pharmaceuticals or as agents in medicinal chemistry.
  • Chemical Modifications: The presence of the 4-methoxyphenyl substituents suggests that this compound can undergo various chemical reactions, which may lead to the synthesis of new derivatives with tailored properties and enhanced biological activity.
  • Biological Significance: Indoles and their derivatives have been found to exhibit a range of biological effects, including antifungal, antibacterial, and anticancer properties. Researchers are continually exploring compounds like this one for their therapeutic potential.
  • Material Science: The unique electronic and steric properties of such compounds make them suitable candidates for applications in material science, including organic semiconductors and light-emitting devices.

In conclusion, 2,3-bis(4-methoxyphenyl)-1H-indole stands as a testament to the intricate world of chemical compounds, highlighting not just the beauty of its structure but also the vast possibilities it presents for future research and application in various scientific fields. As the chemistry community continues to explore, who knows what new discoveries await through the investigation of this indole derivative!

Synonyms
INDOXOLE
Indoxol
5034-76-4
2,3-Bis(4-methoxyphenyl)-1H-indole
Indoxolum
2,3-Bis(p-methoxyphenyl)indole
Indossolo
Indossolo [DCIT]
U-22020
Indoxol [INN-Spanish]
Indoxole [USAN:INN]
Indoxolum [INN-Latin]
UNII-Q0CKS2CL3G
1H-Indole, 2,3-bis(4-methoxyphenyl)-
Q0CKS2CL3G
Indole, 2,3-bis(p-methoxyphenyl)-
NSC-82959
Indoxole (USAN)
INDOXOLE [USAN]
INDOXOLE [INN]
NSC 82959
U 22020
2,3-bis(4-methoxyphenyl)indole
DTXSID70198382
Indoxol (INN-Spanish)
Indoxolum (INN-Latin)
DTXCID00120873
Indole, 2,3-bis(p-methoxyphenyl)-(8CI)
NSC82959
NCIOpen2_009060
Oprea1_487883
Oprea1_566586
SCHEMBL42592
CHEMBL2104332
Indole,3-bis(p-methoxyphenyl)-
2, 3-Bis(p-methoxyphenyl)indole
1H-Indole,3-bis(4-methoxyphenyl)-
NS00125402
D04534
Q27286852