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Saccharin

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Identification
Molecular formula
C7H5NO3S
CAS number
81-07-2
IUPAC name
2,3-dihydro-1,2-benzothiazole 1,1-dioxide
State
State

At room temperature, saccharin is a solid. It is typically found in a crystalline or powder form, which makes it easy to handle and use as a sweetening agent. Due to its high thermal stability, it can be used in a wide range of temperature conditions.

Melting point (Celsius)
228.80
Melting point (Kelvin)
501.80
Boiling point (Celsius)
287.00
Boiling point (Kelvin)
560.00
General information
Molecular weight
183.19g/mol
Molar mass
183.1870g/mol
Density
1.8300g/cm3
Appearence

Saccharin appears as a white, crystalline powder. It may also appear as colorless crystals. It is known for its intense sweet taste, which is approximately 300 to 400 times sweeter than sucrose (table sugar). This compound is used primarily as a calorie-free sweetener in various food products.

Comment on solubility

Solubility of 2,3-Dihydro-1,2-benzothiazole 1,1-dioxide

2,3-Dihydro-1,2-benzothiazole 1,1-dioxide, a sulfur-containing heterocyclic compound, exhibits some intriguing characteristics regarding its solubility:

  • Solvent Dependence: The solubility of this compound is largely dependent on the nature of the solvent used. It typically dissolves well in polar organic solvents.
  • Water Interaction: Due to its structural features, it shows limited solubility in water, making it unsuitable for aqueous solutions without specific modifications.
  • Hydrophobic Properties: The benzothiazole moiety contributes to its hydrophobic character, which can hinder its dissolution in polar solvents.

In summary, while 2,3-dihydro-1,2-benzothiazole 1,1-dioxide is soluble in various organic solvents, its low water solubility is a significant consideration for applications where aqueous environments are needed. It's essential to choose the right solvent to ensure proper dissolution and activity of this compound.

Interesting facts

Interesting Facts about 2,3-Dihydro-1,2-benzothiazole 1,1-dioxide

2,3-Dihydro-1,2-benzothiazole 1,1-dioxide is a compound belonging to the class of benzothiazole derivatives, which are known for their intriguing chemical properties and diverse applications. Here are some noteworthy aspects of this compound:

  • Medicinal Chemistry: Compounds similar to 2,3-dihydro-1,2-benzothiazole 1,1-dioxide routinely appear in drug discovery due to their potential pharmacological activities. They have been studied for their ability to exhibit antimicrobial and anti-inflammatory properties.
  • Structural Significance: The unique fusion of the benzene ring with a thiazole ring not only imparts distinctive chemical behavior but also influences the electronic properties of the compound, making it a valuable subject for researchers interested in organic synthesis.
  • Reaction Versatility: The presence of the sulfinyl group enhances the compound's reactivity, allowing it to participate in various chemical reactions, such as nucleophilic substitutions and cycloadditions, making it a target for synthetic chemists.
  • Properties in Materials Science: Benzothiazole derivatives often play crucial roles in the development of materials. This specific compound has been explored for its potential applications in the field of polymers and advanced coatings.
  • Environmental Chemistry: Some studies have suggested that benzothiazoles may have implications in environmental science, particularly concerning their biodegradability and impact on ecosystems, thus providing an angle of interest for researchers focused on environmental sustainability.

As studies continue to unfold, 2,3-dihydro-1,2-benzothiazole 1,1-dioxide holds promise not just as a chemical compound, but as a gateway to innovative solutions in both medicine and materials science. According to recent research, "the exploration of benzothiazole derivatives remains at the forefront of current synthetic methods and application development," highlighting their significance in modern chemistry.

Synonyms
936-16-3
Benzylsultam
1,2-benzisothiazoline 1,1-dioxide
2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
NSC-362815
BENZ(D)ISOTHIAZOLINE 1,1-DIOXIDE
2,3-DIHYDROBENZ(D)ISOTHIAZOLE 1,1-DIOXIDE
840-640-5
2,3-Dihydrobenzo[d]isothiazole 1,1-dioxide
2,3-Dihydro-1,1-dioxo-1,2-benzisothiazole
1,2-Benzisothiazole, 2,3-dihydro-, 1,1-dioxide
2,3-dihydro-1,2-benzothiazole 1,1-dioxide
1,2-Bitdo
1,2-Benzoisothiazoline 1,1-dioxide
ZLO53QJF59
UNII-ZLO53QJF59
MFCD03426201
NSC362815
NSC 362815
SCHEMBL61176
CHEMBL81566
2,3-DIHYDRO-1??,2-BENZOTHIAZOLE-1,1-DIONE
DTXSID80239477
GVYVHZKTSVDMNT-UHFFFAOYSA-N
AAA93616
XH1316
AKOS006276699
AB92834
CS-W005895
DS-7771
2,3-Dihydrobenzo[d]isothiazole1,1-dioxide
2,3-dihydro-1,2-benzoisothiazole 1,1-dioxide
D16481
EN300-312734
Q27295703
F1905-7319
Z1198162686