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2,3-Dihydrobenzofuran

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Identification
Molecular formula
C8H8O
CAS number
496-16-2
IUPAC name
2,3-dihydrobenzofuran
State
State

At room temperature, 2,3-dihydrobenzofuran is in a liquid state.

Melting point (Celsius)
-40.00
Melting point (Kelvin)
233.15
Boiling point (Celsius)
173.00
Boiling point (Kelvin)
446.15
General information
Molecular weight
134.18g/mol
Molar mass
134.1750g/mol
Density
1.0966g/cm3
Appearence

2,3-Dihydrobenzofuran is a colorless liquid with a characteristic aromatic odor.

Comment on solubility

Solubility of 2,3-dihydrobenzofuran

2,3-dihydrobenzofuran is a fascinating compound when it comes to its solubility characteristics. This organic compound displays moderate solubility in various solvents, which can be attributed to its unique structural properties. Here are some key points about its solubility:

  • Polar Solvents: 2,3-dihydrobenzofuran is more soluble in polar solvents such as ethanol and methanol. This is due to the ability of these solvents to engage in dipole-dipole interactions and hydrogen bonding with the compound.
  • Non-Polar Solvents: It also dissolves reasonably well in non-polar solvents like hexane and benzene, thanks to its hydrophobic aromatic structure that allows for van der Waals interactions.
  • Water Solubility: However, its solubility in water is limited. The presence of an aromatic ring generally reduces solubility in polar protic solvents due to decreased ability to form significant hydrogen bonds.

To sum up, the solubility of 2,3-dihydrobenzofuran can be described as:

  1. Moderately soluble in polar solvents.
  2. Reasonably soluble in non-polar solvents.
  3. Limited solubility in water.

Overall, its solubility features make 2,3-dihydrobenzofuran versatile in various chemical applications, despite its constraints in aqueous environments. When working with this compound, consider the choice of solvent carefully to ensure optimal reactivity and interaction!

Interesting facts

Interesting Facts about 2,3-Dihydrobenzofuran

2,3-Dihydrobenzofuran is a fascinating organic compound that holds significance in both synthetic and natural chemistry. Here are some compelling insights into this intriguing molecule:

  • Structural Characteristics: This compound features a unique bicyclic structure, which is a fusion of a benzene ring and a tetrahydrofuran moiety. This architecture contributes to its interesting chemical properties and reactivity.
  • Biological Relevance: 2,3-Dihydrobenzofuran derivatives have been studied for their potential therapeutic applications. Researchers are examining their roles in drug design, particularly for conditions such as neurodegenerative diseases.
  • Reactivity: The presence of both aromatic and aliphatic characteristics in 2,3-dihydrobenzofuran makes it a versatile compound in chemical reactions. It can undergo various transformations such as oxidation, reduction, and electrophilic substitution.
  • Environmental Aspect: Compounds like 2,3-dihydrobenzofuran are also of interest in environmental chemistry, particularly in studies relating to the biodegradation of organic pollutants.
  • Synthesis: This compound can be synthesized through different methods, including methods utilizing the Diels-Alder reaction, which highlights the importance of cycloaddition reactions in organic synthesis.

In summary, 2,3-dihydrobenzofuran represents a remarkable compound that bridges the gap between synthetic utility and biological significance. As scientists continue to explore its properties and applications, we may uncover even more about its potential in various fields of research.

Synonyms
2,3-DIHYDROBENZOFURAN
496-16-2
Coumaran
Benzofuran, 2,3-dihydro-
Dihydrobenzofuran
Dihydrocoumarone
EINECS 207-817-3
CHEBI:87607
COUMARAN [MI]
99E861415L
DTXSID2022040
DTXCID402040
207-817-3
inchi=1/c8h8o/c1-2-4-8-7(3-1)5-6-9-8/h1-4h,5-6h
2,3-dihydrobenzo[b]furan
2,3-Dihydro-1-benzofuran
2,3-Dihydro-benzofuran
MFCD00005855
Kumaran
2,3-dihydrobenzofurane
CHEMBL370688
2,3-dihydrobenzo(b)furan
UNII-99E861415L
1,2-dihydrobenzofuran
2,3-dihydro-benzofura
2,3-di-hydrobenzofuran
SCHEMBL33192
SCHEMBL155424
2,3-Dihydro-1-benzofuran #
2,3-Dihydrobenzofuran, 99%
Coumaran (2,3-dihydrobenzofuran)
CS-M0160
STR03933
Coumaran; 2,3-Dihydrobenzo[b]furan
BDBM50168006
AKOS000121274
AC-7075
FD11170
PS-4599
HY-75247
SY003884
DB-019755
DB-346445
D1583
NS00031919
EN300-21620
F10902
2,3-Dihydrobenzofuran, purum, >=97.0% (GC)
Q27159770
F0001-1291
Z104505448