2,3-Dihydro-1H-1,2,4-triazolo[4,5-d]pyrimidine-5,7-dione

Identification

Molecular formula

C₅H₄N₄O₂

CAS number

None available

IUPAC name

2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione

State

This compound is a solid at room temperature.

Melting point (Celsius)

330.00

Melting point (Kelvin)

603.15

Boiling point (Celsius)

360.00

Boiling point (Kelvin)

633.15

General information

Molecular weight

154.11g/mol

Molar mass

154.1210g/mol

Density

2.0700g/cm³

Appearence

The compound typically exists as a crystalline solid, usually appearing as white or off-white powder. It is known for its stability as a crystalline substance and will often be stored in a dry and cool environment to maintain its solid-state integrity.

Comment on solubility

Solubility of 2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione

The solubility of 2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione can be described as follows:

Polar solvents: This compound is generally soluble in polar solvents such as water and methanol. This is attributed to the presence of nitrogen atoms in the triazole and pyrimidine rings, which can engage in hydrogen bonding.
Non-polar solvents: However, it shows limited solubility in non-polar solvents like hexane or chloroform, reflecting the nature of its chemical structure.
pH Dependency: The solubility may also vary with changes in pH; in acidic or basic conditions, the solubility can increase due to protonation or deprotonation of functional groups.

In practice, it’s important to note that solubility can significantly influence the compound's bioavailability and reactivity in various applications. Thus, this compound may exhibit interesting behaviors in both pharmaceutical formulations and chemical syntheses. When dealing with such compounds, always consider the solvent used for dissolving, as this can drastically affect your results.

Interesting facts

Interesting Facts about 2,3-Dihydrotriazolo[4,5-d]pyrimidine-5,7-dione

2,3-Dihydrotriazolo[4,5-d]pyrimidine-5,7-dione is a fascinating compound that sits at the intersection of heterocyclic chemistry and medicinal chemistry. Here are some key facts that showcase its intriguing properties:

Structure & Uniqueness: This compound is known for its unique triazolo and pyrimidine fusion, leading to interesting electronic properties and reactivity patterns that make it a valuable subject of study.
Biological Activity: Compounds within this structural family have been researched for their potential pharmacological activities. Many exhibit promising results as antimicrobial and anti-inflammatory agents, opening avenues for new therapeutic applications.
Research Applications: The ability to synthesize derivatives of 2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione has enhanced its utility in drug development, making it a topic of interest in ongoing pharmaceutical research.
Synthetic Pathways: The synthesis of this compound often involves multi-step reactions, showcasing the ingenuity of synthetic chemists in creating complex molecules from simpler precursors.
Interdisciplinary Interest: The exploration of this compound crosses various fields, including organic chemistry, pharmacology, and medicinal chemistry, demonstrating the interconnected nature of modern scientific research.

As chemists continue to explore the capabilities of 2,3-dihydrotriazolo[4,5-d]pyrimidine-5,7-dione, it serves as a prime example of how small changes in molecular structure can lead to significant variations in activity and function in diverse applications. This compound not only intrigues researchers due to its unique properties but also inspires new ideas and innovations in the field of drug design.