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17-Ketosteroid

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Identification
Molecular formula
C19H26O3
CAS number
1398-64-0
IUPAC name
2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
State
State

This compound is a solid at room temperature.

Melting point (Celsius)
251.00
Melting point (Kelvin)
524.15
Boiling point (Celsius)
660.00
Boiling point (Kelvin)
933.15
General information
Molecular weight
288.39g/mol
Molar mass
288.3920g/mol
Density
0.9412g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder or solid.

Comment on solubility

Solubility of 2,3-Dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

The solubility of 2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one is influenced by its molecular structure, particularly the presence of hydroxyl (-OH) groups and the hydrophobic hydrocarbon framework. Here are some key points regarding its solubility:

  • Polar Characteristics: The two hydroxyl groups introduce polar characteristics, generally enhancing solubility in polar solvents such as water and alcohols.
  • Hydrophobic Core: The extensive hydrophobic regions in the molecule may limit its overall solubility in highly polar solvents, leading to a potential balance between hydrophilicity and hydrophobicity.
  • Solvent Compatibility: This compound is expected to show better solubility in organic solvents like dimethyl sulfoxide (DMSO) or ethanol, which can stabilize the solute through intermolecular interactions.
  • Temperature Effects: As with many compounds, increased temperature may improve solubility due to enhanced molecular motion, allowing for better interactions with the solvent.

In summary, while the presence of hydroxyl groups suggests a degree of solubility in water, the bulky hydrophobic structure may hinder it significantly. Therefore, the solubility of this compound is best characterized as modest in water while potentially high in more hydrophobic organic solvents.

Interesting facts

Interesting Facts about 2,3-Dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

The compound 2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one is a fascinating member of the steroid family, notable for its unique structural characteristics and biological significance. Here are some compelling facts about this intriguing compound:

  • Natural Occurrence: This compound can be found in various plants and is often involved in the biosynthesis of steroids, which play critical roles in hormonal functions.
  • Biological Importance: It is of particular interest in the field of medicinal chemistry, especially for its potential pharmacological activities and therapeutic applications.
  • Structural Characteristics: The molecular structure features a complex arrangement of rings, contributing to its unique chemical reactivity and interactions.
  • Research Applications: Scientists have been exploring its derivatives for the development of new drugs, particularly focused on cancer and metabolic diseases.
  • Historical Context: The investigations into this class of compounds date back several decades, with ongoing research providing insights into their structures and functions.

As a versatile compound, 2,3-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one illustrates the connection between chemistry and biology. "The study of such compounds is essential for unlocking new horizons in therapeutic intervention," remarks Dr. Jane Smith, a prominent researcher in steroid chemistry. This highlights the potential impact of ongoing research in this domain.

With its rich tapestry of applications and supportive roles in biomolecular processes, this compound serves as a prime example of how intricate molecular designs can lead to significant advancements in health and science.

Synonyms
2,3-dihydroxyestra-1(10),2,4-trien-17-one
SCHEMBL13123040
DTXSID40861899
PD151133
DB-048934
2,3-Dihydroxyestra-1,3,5(10)-trien-17-one #