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Histidine phosphate

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Identification
Molecular formula
C6H11N3O5P
CAS number
30806-67-0
IUPAC name
[2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate
State
State
At room temperature, histidine phosphate is a solid. This compound is usually handled in powder form for laboratory applications.
Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
190.00
Boiling point (Kelvin)
463.15
General information
Molecular weight
206.15g/mol
Molar mass
206.1330g/mol
Density
1.7914g/cm3
Appearence

Histidine phosphate is typically a white to off-white solid. It may exist in crystalline form depending on its preparation.

Comment on solubility

Solubility Insights for [2,3-Dihydroxy-3-(1H-imidazol-5-yl)propyl] Dihydrogen Phosphate

[2,3-Dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate, with the chemical formula C6H11N3O5P, exhibits interesting solubility characteristics that are important for various applications.

Factors Influencing Solubility

The solubility of this compound can be influenced by several key factors:

  • Polarity: The presence of hydroxyl groups and the phosphate moiety increases its polarity, enhancing its solubility in polar solvents such as water.
  • Temperature: Generally, solubility can increase with temperature; thus, heating the solvent might lead to improved solubility of the compound.
  • pH of the Solution: The protonation state of the imidazole group can alter solubility, making it pH-dependent.

General Solubility Profile

While specific solubility data may vary, it is commonly observed that:

  • This compound is likely to be soluble in water due to its hydrophilic functional groups.
  • Limited solubility might occur in non-polar solvents, given its polar nature.

Thus, [2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate serves as an excellent example of how structural features can significantly influence the solubility properties of chemical compounds, which is crucial for their effective utilization in chemical processes and biological systems.

Interesting facts

Interesting Facts about [2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate

[2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate, a fascinating compound, belongs to a class of derivatives known as phosphates. This compound is of particular interest due to its potential applications in various scientific fields:

  • Bioactivity: Compounds that include imidazole structures are often biologically active, making them essential in pharmacology and medicinal chemistry. They can mimic natural compounds in biological systems.
  • Role in Biochemistry: Phosphate groups are key players in energy transfer within cells, particularly in the form of adenosine triphosphate (ATP), and understanding compounds like this one can provide insights into cellular metabolism.
  • Versatile Reactivity: The hydroxyl groups in this compound allow for diverse chemical reactions, including esterification and nucleophilic substitution, expanding its potential utility in synthetic organic chemistry.
  • Structural Diversity: The presence of multiple functional groups could enhance the compound's solubility and interaction with other chemical entities, making it valuable for drug formulation strategies.

As a scientist, the exploration of compounds like [2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl] dihydrogen phosphate exemplifies the intricate interplay between structure and function in chemistry. "Understanding such compounds not only enriches our knowledge of molecular behavior but also aids in the development of innovative solutions for real-world applications." This compound is indeed an exciting area of research for students and chemists alike!

Synonyms
27982-01-0
imidazole glycerol phosphate
imidazoleglycerol phosphate
2,3-dihydroxy-3-(1h-imidazol-5-yl)propyl dihydrogen phosphate
DTXSID40950676
1,2,3-Propanetriol, 1-imidazol-4(or 5)-yl-, 3-phosphate
1,2,3-Propanetriol,1-imidazol-4-yl-, 3-(dihydrogen phosphate)
2,3-dihydroxy-3-(1H-imidazol-4-yl)propoxyphosphonic acid
[2,3-Dihydroxy-3-(1H-imidazol-5-yl)propyl]dihydrogen phosphate
1,2,3-Propanetriol, 1-(1H-imidazol-4-yl)-, 3-(dihydrogen phosphate)