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7-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole

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Identification
Molecular formula
C22H25N3O3
CAS number
116539-58-7
IUPAC name
2,3-dihydroxybutanedioic acid;7-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole
State
State

At room temperature, the compound is typically found as a solid substance. It may be powdery or crystalline in form, depending on its specific preparation and handling.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
435.00
Boiling point (Kelvin)
708.15
General information
Molecular weight
402.46g/mol
Molar mass
402.4580g/mol
Density
1.7600g/cm3
Appearence

The compound is typically crystalline in nature and may appear in various colors ranging from pale yellow to tan. It often has a characteristic smell depending on its purity and the presence of any residual solvents or impurities.

Comment on solubility

Solubility of 2,3-Dihydroxybutanedioic Acid; 7-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole

The solubility of the compound 2,3-dihydroxybutanedioic acid (also known as tartaric acid) along with 7-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole is influenced by its unique structure, which includes both polar and non-polar functional groups. Generally, solubility can be assessed through the following considerations:

  • Polarity: The presence of hydroxyl (-OH) groups in 2,3-dihydroxybutanedioic acid contributes to strong hydrogen bonding with water, enhancing its solubility in polar solvents.
  • Hydrophobic interactions: The hydrophobic regions of the piperazine and indole structures may lead to reduced solubility in purely aqueous environments, promoting the compound’s solubility in organic solvents.
  • pH-dependent behavior: The acidic and basic functionalities can also affect solubility depending on the pH of the solution, with potential ionization leading to increased solubility.

Moreover, laboratory tests reveal that:

  • The amine and ether linkages can create compatible interactions with a range of solvents, particularly those that are slightly polar.
  • The combined influence of molecular structure implies varying levels of solubility across different solvents, indicating a need for specific solvent choice in practical applications.

In conclusion, understanding the solubility characteristics of this compound necessitates a closer look at its molecular architecture, leading to diverse solubility profiles in multiple environments.

Interesting facts

Interesting Facts about 2,3-Dihydroxybutanedioic Acid; 7-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]-5H-[1,3]dioxolo[4,5-f]indole

This compound is a fascinating example of how complex chemical structures can be engineered to enhance biological activity. Here are some striking features:

  • Dual Functionality: The presence of 2,3-dihydroxybutanedioic acid suggests that this compound may have both carboxylic acid and hydroxyl functionalities, providing it with important properties such as potential antioxidant activity.
  • Pharmacological Interest: The piperazine moiety within the compound is often associated with various pharmacological activities, including antidepressant and antipsychotic effects. This makes it a subject of intense research in medicinal chemistry.
  • Versatile Derivatives: The methoxy group in the structure hints at possible modulation of lipophilicity, which can influence the compound’s ability to cross biological membranes and interact within the body.
  • Cyclic Structures: The inclusion of the [1,3]dioxolo ring system is intriguing as it may provide unique reactivity and stability, potentially opening avenues for new synthetic methodologies.
  • Complex Synthesis: The synthesis of such a compound typically involves multiple steps, showcasing the creativity and intricate planning required in organic synthesis.

In summary, this compound not only illustrates the beauty of organic chemistry but also the potential for real-world applications in pharmaceuticals. As researchers continue to explore its properties, we anticipate uncovering even more interesting facets of its chemistry and ways it can be utilized in therapeutic contexts.

Synonyms
MLS002703972
SCHEMBL613789
CHEMBL1698058
SMR001570682