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2,3-Dimethyl-6-nitroindole

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Identification
Molecular formula
C10H10N2O2
CAS number
10075-16-8
IUPAC name
2,3-dimethyl-6-nitro-1H-indole
State
State

At room temperature, 2,3-Dimethyl-6-nitroindole is a solid.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
188.20g/mol
Molar mass
188.1930g/mol
Density
1.3085g/cm3
Appearence

2,3-Dimethyl-6-nitroindole typically appears as a solid crystalline powder. The color can vary depending on the purity and form of the sample but generally presents as a yellow to brownish-yellow color due to the presence of the nitro group.

Comment on solubility

Solubility Overview of 2,3-Dimethyl-6-nitro-1H-indole

The solubility of 2,3-dimethyl-6-nitro-1H-indole can be quite intriguing, given its unique structural characteristics. Understanding its solubility properties is essential for its application in various fields.

Key Factors Influencing Solubility:

  • Polarity: The presence of the nitro group (-NO2) contributes to the polarity of the molecule, potentially enhancing its solubility in polar solvents.
  • Hydrophobic Interactions: The dimethyl groups may introduce hydrophobic character, which can lead to lower solubility in polar solvents while possibly increasing solubility in organic solvents.
  • Temperature: Solubility often increases with temperature, so higher thermal conditions may aid in dissolving 2,3-dimethyl-6-nitro-1H-indole.

In general, compounds like 2,3-dimethyl-6-nitro-1H-indole typically exhibit variable solubility across different solvents. Here are some observations:

  1. Water: Likely low solubility due to the hydrophobic dimethyl groups.
  2. Organic Solvents: Enhanced solubility in solvents such as ethanol or acetone.
  3. Aqueous Solutions: Solubility may be improved in basic or acidic solutions due to protonation or deprotonation effects.

In summary, while 2,3-dimethyl-6-nitro-1H-indole may not be highly soluble in water, its behavior in organic solvents and variations in specific conditions can lead to significant solubility. Understanding these nuances is vital for effectively utilizing this compound in scientific applications.

Interesting facts

Interesting Facts about 2,3-Dimethyl-6-nitro-1H-indole

2,3-Dimethyl-6-nitro-1H-indole is a fascinating compound that explores the intersection of organic chemistry and biological applications. Here are some noteworthy points:

  • Structure and Functionality: This compound is a derivative of indole, a bicyclic structure known for its presence in many biologically significant compounds, including indole alkaloids.
  • Nitro Substitution: The presence of a nitro group at the 6-position makes this compound particularly interesting, as nitro groups are known to enhance the compound's reactivity and potential use in various applications, such as dyes and agrochemicals.
  • Biological Relevance: Indole derivatives have been widely studied for their roles in biological systems, and compounds like 2,3-dimethyl-6-nitro-1H-indole may exhibit noteworthy pharmacological activities.
  • Synthetic Pathways: The synthesis of this compound can involve various sophisticated organic reactions, making it a great subject for students and researchers interested in synthetic organic chemistry.
  • Applications in Research: The compound may play a role in drug discovery, particularly in the search for new pharmaceuticals targeting a variety of diseases, given the therapeutic potential of nitroindoles.

In conclusion, 2,3-Dimethyl-6-nitro-1H-indole is not merely a chemical formula; it represents a host of possibilities in scientific exploration. As quoted by renowned chemist Marie Curie, “Nothing in life is to be feared, it is only to be understood.” This compound exemplifies the beauty of understanding through the lens of chemistry.

Synonyms
2,3-dimethyl-6-nitro-1H-indole
13801-00-8
2,3-Dimethyl-6-nitroindole
INDOLE, 2,3-DIMETHYL-6-NITRO-
NSC 88617
1H-Indole, 2,3-dimethyl-6-nitro-
BRN 0179788
NSC88617
Indole,3-dimethyl-6-nitro-
5-20-07-00109 (Beilstein Handbook Reference)
SCHEMBL17678042
SCHEMBL31326014
1H-Indole,3-dimethyl-6-nitro-
DTXSID20160453
NAA80100
NSC-88617
WLN: T56 BMJ C1 D1 HNW
EN300-1084738
Q63399052