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Berberine chloride

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Identification
Molecular formula
C20H18ClNO4
CAS number
633-65-8
IUPAC name
2,3,10,11-tetramethoxy-8-methyl-isoquinolino[2,1-b]isoquinolin-7-ium;chloride
State
State

In a solid state at room temperature, berberine chloride is usually available as a powder.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
371.81g/mol
Molar mass
371.8090g/mol
Density
1.3004g/cm3
Appearence

Berberine chloride appears as a yellow solid at room temperature. It is a vibrant, crystalline powder often used for its dyeing properties as well as its medicinal uses.

Comment on solubility

Solubility Overview

The compound 2,3,10,11-tetramethoxy-8-methyl-isoquinolino[2,1-b]isoquinolin-7-ium; chloride presents intriguing characteristics regarding its solubility.

General Solubility Characteristics

In the context of solubility, one can consider the following:

  • Polarity: Due to the presence of multiple methoxy groups and the ionic nature of the chloride, the compound demonstrates both polar and non-polar characteristics.
  • Aqueous Solubility: Typically, larger and more complex organic compounds can exhibit lower aqueous solubility. However, the ionic chloride component may enhance overall solubility in polar solvents.
  • Solvent Specificity: The solubility behavior can vary significantly depending on the solvent type. Organic solvents, such as methanol or ethanol, may facilitate better solubility compared to water.

Implications of Solubility

Understanding the solubility of this compound is crucial for practical applications, as it can:

  • Influence the compound’s bioavailability in pharmaceutical formulations.
  • Affect the extraction processes in chemical synthesis.
  • Assist in predicting stability and reactivity under various conditions.

In summary, the solubility of 2,3,10,11-tetramethoxy-8-methyl-isoquinolino[2,1-b]isoquinolin-7-ium; chloride is a fascinating subject that reflects the interplay of chemical structure and solvent interactions. Its unique attributes and potential for varied solubility behaviors warrant further investigation in both scientific research and practical applications.

Interesting facts

Interesting Facts about 2,3,10,11-Tetramethoxy-8-methyl-Isoquinolino[2,1-b]isoquinolin-7-ium Chloride

2,3,10,11-tetramethoxy-8-methyl-isoquinolino[2,1-b]isoquinolin-7-ium;chloride is a fascinating compound that showcases the intricate world of organic chemistry, particularly in the realm of alkaloids and isoquinoline derivatives. Here are some notable aspects:

  • Structural Complexity: This compound features a complex isoquinoline framework. Isoquinolines are known for their structural diversity, and this compound is no exception with its multiple methoxy groups and unique methyl substitution.
  • Biological Significance: Compounds related to isoquinolines are known for various biological activities, including anti-inflammatory, analgesic, and antimicrobial properties. Studying such compounds can lead to the development of new pharmaceuticals.
  • Complexity in Synthesis: The synthesis of this compound involves advanced organic reactions and careful manipulation of reaction conditions. This makes it an excellent subject of study for organic chemistry students learning about multi-step synthesis.
  • Electrochemistry: The ionic nature of the chloride salt adds interesting electrochemical properties to the compound, which can be studied using voltammetry techniques to understand electron transfer processes.

The presence of multiple methoxy groups not only influences the compound's reactivity and interactions but also its solubility and stability in aqueous environments. Therefore, the study of this compound isn't just about its molecular structure but also about its functional implications in various chemical and biological contexts.

In summary, the compound 2,3,10,11-tetramethoxy-8-methyl-isoquinolino[2,1-b]isoquinolin-7-ium;chloride exemplifies the beauty of organic chemistry's complexity, offering insights into both synthesis and potential applications.

Synonyms
Coralyne chloride
38989-38-7
EINECS 254-239-2
NSC 96349
NSC 154891
8-Methyl-2,3,10,11-tetramethoxydibenzo(a,g)quinolizinium chloride
DIBENZO(a,g)QUINOLIZINIUM, 8-METHYL-2,3,10,11-TETRAMETHOXY-, CHLORIDE
Dibenzo(a,g)quinolizinium, 2,3,10,11-tetramethoxy-8-methyl-, chloride
Dibenzo(a,g)quinolizinium, 2,3,10,11-tetramethoxy-8-methyl-, chloride (9CI)
Coralyne
Coralyne (chloride)
6872-73-7
NSC96349
2,3,10,11-tetramethoxy-8-methylisoquinolino[2,1-b]isoquinolin-7-ium;chloride
(-)-Coralyn chloride
Dibenzo[a, 2,3,10,11-tetramethoxy-8-methyl-, chloride
(-)-Coralyne chloride hydrate
(-)-Coralyne chloride
5,6,7,8,13,13a-Hexadehydro-8-methyl-2,3,10,11-tetramethoxyberbinium chloride
SPECTRUM1500861
CHEMBL363506
SCHEMBL3320097
DTXSID50959832
PDYBUYVOPAJLKP-UHFFFAOYSA-M
HMS1921K20
2,3,10,11-Tetramethoxy-8-methyldibenzo(a,g)quinolizinium chloride
5,6,7,8,13,13a-Hexahydro-8-methyl-2,3,10,11-tetramethoxyberbinium
CCG-38524
NSC-96349
NSC154891
AKOS024348916
FC66373
NSC-154891
?NSC-154890
BERBINIUM, 5,6,7,8,13,13a-HEXADEHYDRO-2,3,10,11-TETRAMETHOXY-8-METHYL-, CHLORIDE
NCGC00094866-01
NCGC00094866-02
MS-26783
HY-118581
CS-0067506
NS00057636
G12056
SR-05000002641
SR-05000002641-1
2,3,10,11-Tetramethoxy-8-methylisoquinolino[3,2-a]isoquinolin-7-ium chloride