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2,3,3-trimethylindole

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Identification
Molecular formula
C11H13N
CAS number
2485-29-2
IUPAC name
2,3,3-trimethylindole
State
State
2,3,3-Trimethylindole is in the form of a crystalline solid at room temperature.
Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.15
General information
Molecular weight
171.25g/mol
Molar mass
171.2530g/mol
Density
1.0710g/cm3
Appearence

2,3,3-Trimethylindole is typically a pale yellow to white crystalline solid. Its appearance can vary slightly depending on its purity and form, but it generally maintains a crystalline texture.

Comment on solubility

Solubility of 2,3,3-trimethylindole

2,3,3-trimethylindole, a conjugated compound characterized by its complex aromatic structure, exhibits distinct solubility properties influenced by its chemical nature:

  • Solvent Interaction: The solubility of 2,3,3-trimethylindole is highly dependent on the solvent used. It shows good solubility in nonpolar organic solvents such as hexane and toluene.
  • Polar Solvents: In contrast, its solubility in polar solvents, like water, is quite limited due to the inability of the compound to form significant hydrogen bonds.
  • Temperature Influence: As is common with many organic compounds, solubility may increase with temperature; thus, warm solutions of nonpolar solvents can enhance the dissolution of 2,3,3-trimethylindole.
  • pH Impact: The pH of the solution can also play a role, although 2,3,3-trimethylindole itself is not highly acidic or basic.

In summary, it is essential to consider the nature of the solvent and the conditions when assessing the solubility of 2,3,3-trimethylindole. As a rule of thumb, like dissolves like, so the compound will favor solubility in nonpolar environments, ensuring effective usage in relevant chemical applications.

Interesting facts

Interesting Facts about 2,3,3-Trimethylindole

2,3,3-Trimethylindole is a fascinating compound that falls within the class of indoles, which are pivotal in organic chemistry and biochemistry. This particular indole derivative is known for its unique structure and diverse properties.

Chemical Structure and Characteristics

The structure of 2,3,3-trimethylindole features a bicyclic core that includes a five-membered nitrogen-containing ring. This configuration contributes to its chemical reactivity and helps to explain its role in various biochemical pathways.

Significance in Nature and Chemistry

  • Natural Occurrence: This compound is often found in nature, particularly in certain plants and organisms, playing a role in their metabolic processes.
  • Fragrance and Flavor: 2,3,3-trimethylindole is associated with strong odor profiles and is a key component in the synthesis of fragrances.
  • Biosynthesis: It may be involved in the biosynthesis of certain alkaloids, which are important not only for plant defense mechanisms but also serve as valuable pharmaceuticals.

Applications

This compound has garnered attention in various fields, including:

  • Pharmaceutical Industry: The potential for synthesizing bioactive molecules.
  • Perfume Industry: Acts as a noteworthy compound in the creation of complex scents due to its distinctive odor.
  • Research: Used in studies analyzing neurotransmitters and other biological processes.

Fun Fact

Interestingly, the compound’s name, 2,3,3-trimethylindole, reflects its structure, where the 'trimethyl' prefix denotes the three methyl groups attached to the indole scaffold. This is a great example of how nomenclature in chemistry can reveal important information about a molecule’s structure!

The study of 2,3,3-trimethylindole not only enriches our understanding of indoles but also opens the door to exploring potential applications in various promising scientific domains.

Synonyms
2,3,3-Trimethylindolenine
1640-39-7
2,3,3-TRIMETHYL-3H-INDOLE
3H-Indole, 2,3,3-trimethyl-
CCRIS 6607
EINECS 216-685-6
NSC 65633
DTXSID9049403
AI3-51456
DTXCID8029363
2,3,3Trimethyl3Hindole
3HIndole, 2,3,3trimethyl
216-685-6
2,3,3-trimethylindole
MFCD00005724
2,3,3-Trimethylindolenine (Technical Grade, contain dimer)
2,3,3-trimethyl indolenine
2,3,3-Trimethyl-3H-indole; 2,3,3-Trimethylindole; 3H-2,3,3-Trimethylindole; NSC 65633;
NSC65633
2,3-Trimethylindolenine
2,3,3-trimethyl-indole
2,3-Trimethyl-3H-indole
2,3,3-trimethyl-indolenine
3H-Indole,3,3-trimethyl-
SCHEMBL101153
SCHEMBL6153645
CHEMBL2393311
2,3,3-trimethyl-(3H)-indole
2,3,3-Trimethylindolenine, 98%
Tox21_202974
2,3,3-trimethyl-3H-benzo[b]azole
BBL027538
NSC-65633
STK803583
2,3,3-trimethyl-3H-benzo [b]azole
AKOS000270800
CS-W016176
FT52498
NCGC00260520-01
AC-27778
AS-14403
BP-24359
CAS-1640-39-7
DB-043579
NS00025361
T0766
EN300-33323
D77785
10.14272/FLHJIAFUWHPJRT-UHFFFAOYSA-N.1
doi:10.14272/FLHJIAFUWHPJRT-UHFFFAOYSA-N.1
F0001-0594
Z339406798