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Tropisetron hydrochloride

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Identification
Molecular formula
C20H24NO2Cl
CAS number
105826-92-4
IUPAC name
2,3,3-tris(4-methoxyphenyl)-N,N-dimethyl-prop-2-en-1-amine;hydrochloride
State
State

Tropisetron hydrochloride is typically found in a solid state at room temperature. It is commonly provided in a powder form suitable for pharmaceuticals and other applications.

Melting point (Celsius)
101.00
Melting point (Kelvin)
374.15
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.15
General information
Molecular weight
367.88g/mol
Molar mass
367.8800g/mol
Density
1.1970g/cm3
Appearence

Tropisetron hydrochloride usually appears as a white to off-white crystalline powder. The compound is hygroscopic, meaning it can absorb moisture from the air. It may also come in a powder form that has uniform granules.

Comment on solubility

Solubility of 2,3,3-tris(4-methoxyphenyl)-N,N-dimethyl-prop-2-en-1-amine; hydrochloride

The solubility characteristics of 2,3,3-tris(4-methoxyphenyl)-N,N-dimethyl-prop-2-en-1-amine; hydrochloride can be quite interesting due to its unique structure. As a hydrochloride salt, it often exhibits enhanced solubility compared to its free base form.

Key factors affecting solubility include:

  • Polarity: The presence of the methoxy groups may increase the overall polarity of the compound, allowing for better interaction with polar solvents, such as water.
  • Hydrochloride Formation: The conversion into hydrochloride increases hydrophilicity, subsequently improving solubility in aqueous solutions.
  • Temperature Effects: Like many compounds, solubility may increase with temperature, making it more soluble when heated.

Potential solubility scenarios:

  • **Soluble in water**: Given its hydrochloride form, it is likely to be soluble in water, allowing for easy formulation in aqueous environments.
  • **Moderate solubility in organic solvents**: Depending on the specific solvent polarity, the compound might show varying levels of solubility due to its organic components.

As with many compounds, exact solubility can vary based on factors such as pH, the presence of other ions, and specific solvent characteristics. Thus, experimental validation is important to understand its full solubility profile. Always consult relevant solubility data when examining the practical applications for this compound.

Interesting facts

Interesting Facts about 2,3,3-Tris(4-methoxyphenyl)-N,N-dimethyl-prop-2-en-1-amine; Hydrochloride

This compound, often abbreviated as TMDA-HCl, is a fascinating organic molecule that showcases the diverse applications and structural complexity found within chemical compounds. Here are some intriguing facts about it:

  • Versatile Applications: TMDA-HCl is primarily studied for its role in medicinal chemistry and as a potential active pharmaceutical ingredient (API).
  • Molecular Design: The unique structure of TMDA-HCl, with its multiple methoxyphenyl groups, contributes to its interesting pharmacological properties. The presence of electron-donating methoxy groups enhances the molecule's stability and reactivity.
  • Historical Context: This compound and similar derivatives have been part of extensive research into their effects on neurotransmitter systems, which may lead to novel treatments in neuropharmacology.
  • Research Potential: Studies into TMDA-HCl often explore its interaction with biological targets, making it a valuable compound in the search for new therapeutic agents.
  • Chiral Nature: Since it has asymmetric centers, the compound may exhibit different biological activities based on its stereochemistry, allowing researchers to delve deeper into structure-activity relationships (SAR).

In conclusion, 2,3,3-tris(4-methoxyphenyl)-N,N-dimethyl-prop-2-en-1-amine; hydrochloride is more than just a chemical compound; it represents a bridge between chemical synthesis and biological applications. As we continue to unravel its properties, we uncover new possibilities in the worlds of medicine and pharmaceuticals.

Synonyms
Amotriphene hydrochloride
Aminooxytriphene hydrochloride
Win 5494
UNII-M02V9BH3D0
M02V9BH3D0
ALLYLAMINE, 2,3,3-TRIS(p-METHOXYPHENYL)-N,N-DIMETHYL-, HYDROCHLORIDE
WIN-5494 HYDROCHLORIDE
DTXSID40205350
Benzeneethanamine, 4-methoxy-alpha-(bis(4-methoxyphenyl)methylene)-N,N-dimethyl-, HCl
DTXCID40127841
Benzeneethanamine, 4-methoxy-alpha-(bis(4-methoxyphenyl)methylene)-N,N-dimethyl-, HCl (9CI)
568-69-4
Aminooxytriphene HCl
3-Dimethylamino-1,1,2-tris(4-methoxyphenyl)-1-propene hydrochloride
2,3,3-tris(4-methoxyphenyl)-N,N-dimethylprop-2-en-1-amine;hydrochloride
AKOS040750421
Q27283282