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Protocatechuic aldehyde

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Identification
Molecular formula
C8H8O4
CAS number
139-85-5
IUPAC name
2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde
State
State

At room temperature, protocatechuic aldehyde exists as a solid.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
477.81
Boiling point (Kelvin)
750.96
General information
Molecular weight
168.15g/mol
Molar mass
170.1210g/mol
Density
1.4710g/cm3
Appearence

Protocatechuic aldehyde appears as an off-white to beige crystalline solid.

Comment on solubility

Solubility of 2,3,4-Trihydroxy-6-(hydroxymethyl)benzaldehyde

The solubility of 2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde can be influenced by several factors due to its unique structural characteristics. This compound, often known for its multiple hydroxyl groups, is likely to exhibit varying solubility in different solvents.

Key Points on Solubility:

  • Polar Solvents: Given the presence of several hydroxyl (-OH) groups, this compound tends to be quite soluble in polar solvents such as water and alcohols. The hydroxyl groups can engage in hydrogen bonding with the solvent, facilitating solubility.
  • Non-Polar Solvents: In contrast, solubility in non-polar solvents is expected to be low. The hydrophobic nature of non-polar solvents does not favor the solubilization of highly polar compounds like this one.
  • Concentration Factors: As with many compounds, the temperature and concentration significantly affect solubility. For instance, increasing the temperature often enhances solubility in polar environments.

In summary, it is reasonable to state that 2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde is primarily soluble in polar solvents due to its multiple hydroxyl groups, while its solubility in non-polar solvents remains considerably limited. Understanding these solubility characteristics is crucial for practical applications in various chemical contexts.

Interesting facts

Exploring 2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde

2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde, commonly referred to as a flavonoid compound, presents a plethora of exciting opportunities for scientific exploration. This organic compound is notable for its multiple functional groups, which contribute significantly to its chemical behavior and potential applications.

Key Characteristics and Applications

  • Bioactivity: This compound exhibits remarkable biological activities, including antioxidant properties. It helps in scavenging free radicals, thereby playing a role in protecting cells from oxidative stress.
  • Pharmaceutical Potential: Due to its chemical structure, it has been studied for its potential in drug development, particularly in the realms of anti-inflammatory and anticancer treatments.
  • Chemical Versatility: The presence of hydroxyl groups in its structure enhances its reactivity, making it a useful building block for synthesizing other important compounds in organic chemistry.
  • Natural Occurrence: This compound is often found in various plant species, contributing to the color and flavor of fruits and beverages.

Research Insights

Recent studies have highlighted how compounds like this one can influence cellular mechanisms. For instance, it has been shown to modulate signaling pathways that are crucial for cell survival and growth.

Conclusion

In summary, 2,3,4-trihydroxy-6-(hydroxymethyl)benzaldehyde is not just a simple organic compound; it represents a rich intersection of biology and chemistry. As researchers continue to investigate its properties, the full scope of its impact on health and industry may very well be unveiled.

Synonyms
Fomecin A
2,3,4-Trihydroxy-6-(hydroxymethyl)benzaldehyde
Fomecin
FOMECIN-A
NSC 73231
BRN 2693556
1E2L0W6KK8
NSC-73231
UNII-1E2L0W6KK8
DTXSID60161303
4-08-00-03351 (Beilstein Handbook Reference)
O-TOLUALDEHYDE, .ALPHA.,4,5,6-TETRAHYDROXY-
DTXCID1083794
O-TOLUALDEHYDE, ALPHA,4,5,6-TETRAHYDROXY-
1403-56-1
Benzaldehyde, 2,3,4-trihydroxy-6-(hydroxymethyl)-
SCHEMBL1527103
NSC73231
AKOS006279874
DB-127373
NS00011759
Benzaldehyde,3,4-trihydroxy-6-(hydroxymethyl)-