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2,3,4-Trimethylpyridine

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Identification
Molecular formula
C8H11N
CAS number
583-58-4
IUPAC name
2,3,4-trimethylpyridine
State
State

At room temperature, 2,3,4-Trimethylpyridine is typically found in a liquid state.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
121.18g/mol
Molar mass
121.1820g/mol
Density
0.9180g/cm3
Appearence

2,3,4-Trimethylpyridine is a colorless liquid with a slight aromatic odor. It is miscible with common organic solvents and water, reflecting its utility in various chemical applications.

Comment on solubility

Solubility of 2,3,4-Trimethylpyridine

2,3,4-trimethylpyridine, a member of the pyridine family, exhibits intriguing solubility characteristics. Here are some key points to consider:

  • Polar Nature: The presence of nitrogen in the pyridine ring, coupled with the three methyl groups, influences its polar character.
  • Solvent Compatibility: 2,3,4-trimethylpyridine is known to be soluble in various organic solvents, particularly:
    • Alcohols
    • Ether
    • Aromatic hydrocarbons
    • Chloroform
  • Water Solubility: While not highly soluble in water, it demonstrates some degree of miscibility due to its polar functional groups.
  • Practical Implications: The solubility characteristics make it useful in:
    • Organic synthesis
    • Chemical manufacturing

In summary, the solubility of 2,3,4-trimethylpyridine is governed by its chemical structure, enabling it to dissolve effectively in numerous organic solvents while maintaining limited water solubility.

Interesting facts

Interesting Facts about 2,3,4-Trimethylpyridine

2,3,4-Trimethylpyridine, often referred to as 2,3,4-TMP, is a fascinating compound belonging to the pyridine family, which is a class of nitrogen-containing heterocycles. This compound is not only notable for its chemical structure but also for its diverse applications in various fields.

Key Characteristics and Applications

  • Versatile Solvent: 2,3,4-TMP is a strong polar solvent, making it an excellent choice for various chemical reactions and processes.
  • Intermediate in Synthesis: It serves as an important intermediate in the synthesis of other chemical compounds, particularly in the production of pharmaceuticals and agrochemicals.
  • Catalytic Properties: Due to its unique nitrogen-containing structure, 2,3,4-TMP can act as a catalyst in certain organic reactions.
  • Flavor and Aroma: This compound can be found in various flavor and aroma studies, contributing to the fragrance of several plant extracts.

Chemical Behavior

The presence of multiple methyl groups in its structure significantly influences the reactivity and stability of 2,3,4-TMP. Notably:

  • The substitution patterns on the aromatic ring contribute to its chemical properties, which can be exploited in synthetic chemistry.
  • Its ability to participate in nucleophilic substitution reactions makes it a valuable compound in organic synthesis.

Fun Fact

Interestingly, the trimethyl variants of pyridine are often studied in the context of chiral chemistry, which is vital for the development of asymmetric synthesis strategies in pharmaceuticals. As 2,3,4-TMP is a structural isomer of other trimethylated pyridines, it provides chemists with a rich field for comparison and study.

In summary, 2,3,4-trimethylpyridine stands out not only for its utility in chemical synthesis but also for its contributions to various industries, illustrating the profound complexity hidden within seemingly simple organic compounds.

Synonyms
2,3,4-TRIMETHYLPYRIDINE
2233-29-6
2,3,4-Collidine
Pyridine, 2,3,4-trimethyl-
EINECS 218-775-0
UNII-720P8M59GM
720P8M59GM
DTXSID90176869
DTXCID0099360
218-775-0
hoprxxxsabqwav-uhfffaoysa-n
2,3,4-trimethyl-pyridine
SCHEMBL7488
DB-191877
NS00027132
Q27266001