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2,3,4-Trimethylquinoline

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Identification
Molecular formula
C12H13N
CAS number
578-59-4
IUPAC name
2,3,4-trimethylquinoline
State
State

At room temperature, 2,3,4-Trimethylquinoline is a liquid. It is not particularly volatile, and its physical state is typical of many aromatic amine derivatives, possessing both considerable thermal stability and a characteristic aromatic odor.

Melting point (Celsius)
-56.00
Melting point (Kelvin)
217.15
Boiling point (Celsius)
269.00
Boiling point (Kelvin)
542.15
General information
Molecular weight
171.25g/mol
Molar mass
171.2540g/mol
Density
1.0439g/cm3
Appearence

2,3,4-Trimethylquinoline is a liquid compound characterized by a pale yellow to yellow color. It has a slightly viscous texture. Quinoline derivatives like this one are known for their distinctive, often unpleasant aromatic smell.

Comment on solubility

Solubility of 2,3,4-trimethylquinoline

2,3,4-trimethylquinoline, a derivative of quinoline, exhibits intriguing solubility characteristics due to its unique molecular structure. The solubility of this compound can be influenced by a variety of factors:

  • Polarity: Being a nitrogen-containing heterocyclic compound, 2,3,4-trimethylquinoline features both polar and nonpolar components. This duality affects its solubility in different solvents.
  • Solvent Interaction: It tends to dissolve well in organic solvents such as ethanol, chloroform, and dichloromethane, due to the hydrophobic nature of its alkyl groups.
  • Water Solubility: Generally, 2,3,4-trimethylquinoline is insoluble or only slightly soluble in water. This limited solubility can be attributed to its nonpolar characteristics, which reduce its affinity for polar solvent molecules.

In summary, while 2,3,4-trimethylquinoline displays significant solubility in various organic solvents, its poor solubility in water is a common trait among many alkyl-substituted heterocyclic compounds. Understanding these solubility patterns is crucial for its application in chemical processes and formulations.

Interesting facts

Interesting Facts about 2,3,4-Trimethylquinoline

2,3,4-trimethylquinoline is a fascinating organic compound that belongs to the quinoline family. Here are several compelling aspects of this compound:

  • Structural Characteristics: The compound features a quinoline backbone, which is a bicyclic structure formed by a fused benzene and pyridine ring. The presence of three methyl groups at positions 2, 3, and 4 contributes to its unique chemical properties and reactivity.
  • Biological Importance: Quinoline derivatives, including 2,3,4-trimethylquinoline, are known for their diverse biological activities. Some studies suggest that they exhibit antimicrobial, anti-inflammatory, and potential anticancer properties, making them interesting subjects for pharmaceutical research.
  • Applications in Industry: This compound is not just of academic interest; it finds applications in various industrial processes. It is used in the synthesis of dyes, agrochemicals, and other aromatic compounds.
  • Research Significance: As a member of the quinoline family, 2,3,4-trimethylquinoline serves as a building block for chemical synthesis, including the formation of more complex molecules. It plays a critical role in developing new materials and chemicals.
  • Interesting Fact: The synthesis of 2,3,4-trimethylquinoline often involves the use of multi-step reactions and can highlight the importance of regioselectivity in organic synthesis, as the orientation of methyl group addition critically influences the compound's properties.

In summary, 2,3,4-trimethylquinoline is not just another chemical entity; it's a compound with a rich identity that bridges various fields, from organic chemistry to pharmacology. Its structural attributes, industrial applications, and biological potential make it a subject of continued interest and study in the scientific community.

Synonyms
2,3,4-TRIMETHYLQUINOLINE
2437-72-1
TRIMETHYLQUINOLINE
51366-52-0
Quinoline, 2,3,4-trimethyl-
UNII-7HLP41FH32
7HLP41FH32
DTXSID10947230
DTXCID30933978
inchi=1/c12h13n/c1-8-9(2)11-6-4-5-7-12(11)13-10(8)3/h4-7h,1-3h
vbcfhwspnheyge-uhfffaoysa-n
Quinoline, trimethyl-
SCHEMBL231530
F2124-0969
CAA43772
AKOS006372936
H41112
Q27268304