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Rose Bengal

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Identification
Molecular formula
C20H4Cl4I4Na2O5
CAS number
632-69-9
IUPAC name
2,3,4,5-tetrachloro-6-[3-hydroxy-2,4,5,7-tetrakis(131I)(iodanyl)-6-oxo-xanthen-9-yl]benzoic acid
State
State

At room temperature, Rose Bengal exists as a solid crystalline powder.

Melting point (Celsius)
350.00
Melting point (Kelvin)
623.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
1017.65g/mol
Molar mass
1 017.6450g/mol
Density
3.0567g/cm3
Appearence

Rose Bengal is typically a dark reddish-brown to purple crystalline powder. It has a vibrant color due to its chromophore structure, making it useful as a dye in various applications. When dissolved in a solution, it often appears as an intense pink or magenta coloration.

Comment on solubility

Solubility of 2,3,4,5-tetrachloro-6-[3-hydroxy-2,4,5,7-tetrakis(131I)(iodanyl)-6-oxo-xanthen-9-yl]benzoic acid

The solubility of 2,3,4,5-tetrachloro-6-[3-hydroxy-2,4,5,7-tetrakis(131I)(iodanyl)-6-oxo-xanthen-9-yl]benzoic acid can be influenced by several factors, including its complex structure and the presence of halogenated groups. Here are some key points regarding its solubility:

  • Due to the presence of multiple chloro and iodo substituents, the compound is expected to exhibit a degree of hydrophobicity, which may limit its solubility in polar solvents such as water.
  • The incorporation of hydroxyl groups typically enhances solubility in polar solvents through hydrogen bonding, which might offer some balance against the hydrophobic effects of halogenation.
  • In organic solvents, especially those that can solvate the chlorinated or iodinated components, the compound may show increased solubility.

In summary, the solubility of this compound is anticipated to be moderate, with potential solubility in organic solvents and limited solubility in water. Understanding these solubility characteristics is crucial for applications in various fields, including pharmaceuticals and imaging.

Interesting facts

Interesting Facts about 2,3,4,5-tetrachloro-6-[3-hydroxy-2,4,5,7-tetrakis(¹³¹I)(iodanyl)-6-oxo-xanthen-9-yl]benzoic acid

This complex compound, often abbreviated as tetrachloro-xanthenone, boasts several remarkable features that make it a subject of interest in both academia and applied sciences. Here are some highlights:

  • Radioactive Isotope Use: The presence of 131I (iodine-131) highlights its application in medical imaging and therapy, particularly in treating thyroid conditions. Iodine-131 is renowned for its ability to localize in thyroid tissues.
  • Structural Complexity: The intricate structure of the molecule includes multiple chlorinated substitutions and a unique xanthenone backbone, contributing to its unique chemical behavior and properties.
  • Fluorescence Properties: The xanthenone moiety serves as a fluorescent unit, making this compound suitable for use in fluorescent markers or probes in biological research.
  • Potential Applications: Research suggests potential applications in various fields, such as:
    • Photodynamic therapy
    • Fluorescent tagging in cellular studies
    • Targeted radionuclide therapy
  • Environmental Impact: Studying chlorinated and iodine-containing compounds allows scientists to understand their stability and breakdown in both environmental and human health contexts.

As with many synthetic compounds, the synthesis of tetrachloro-xanthenone may involve intricate reactions and necessitates careful, controlled conditions to avoid unwanted side products. Its combination of radioactive and fluorescent properties creates an exciting platform for interdisciplinary research, bridging the realms of chemistry, materials science, and medical applications.

Synonyms
Rose bengal I-131
MKF129JIZX
UNII-MKF129JIZX
99689-97-1
RefChem:179853