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Pentafluorobenzoic acid

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Identification
Molecular formula
C7HF5O2
CAS number
602-94-8
IUPAC name
2,3,4,5,6-pentafluorobenzoic acid
State
State

At room temperature, pentafluorobenzoic acid is in a solid state, existing as a crystalline powder.

Melting point (Celsius)
109.00
Melting point (Kelvin)
382.15
Boiling point (Celsius)
218.00
Boiling point (Kelvin)
491.15
General information
Molecular weight
196.08g/mol
Molar mass
196.0920g/mol
Density
1.6410g/cm3
Appearence

Pentafluorobenzoic acid appears as a white crystalline solid. It is known for its high fluorine content, which significantly impacts its physical properties, including its melting and boiling points compared to non-fluorinated benzoic acids.

Comment on solubility

Solubility of 2,3,4,5,6-pentafluorobenzoic acid

2,3,4,5,6-pentafluorobenzoic acid is a fascinating compound when it comes to its solubility characteristics. This acid, due to its numerous fluorine atoms, exhibits unique interactions with solvents.

  • Polarity: The presence of five fluorine atoms significantly increases the polarity of the molecule, making it hydrophilic and enhancing its solubility in polar solvents.
  • Solvent Compatibility: It is generally more soluble in protic solvents like water and alcohols compared to nonpolar solvents, given its ability to form hydrogen bonds.
  • Concentration Effects: As the concentration of 2,3,4,5,6-pentafluorobenzoic acid increases, one may observe a saturation point beyond which no further dissolution occurs.
  • Temperature Dependence: The solubility often increases with rising temperature, a common trend for many acids and salts, as it enhances molecular motion and solvent interactions.

In practical applications, understanding its solubility can aid in various fields, influencing its utilization in synthetic processes and analytical chemistry.

As with many chemical compounds, the intricate balance of forces at play makes a compound's solubility a key aspect of its behavior in solution!

Interesting facts

Interesting Facts about 2,3,4,5,6-Pentafluorobenzoic Acid

2,3,4,5,6-Pentafluorobenzoic acid is a fascinating compound that has captured the attention of researchers and chemists alike. Here are some intriguing insights:

  • Fluorinated Compound: The presence of five fluorine atoms significantly enhances its chemical reactivity and affects its physical properties, making it a topic of interest in organic synthesis.
  • Acidic Nature: As a benzoic acid derivative, it showcases acidic behavior, which can be exploited in various organic reactions and applications.
  • Applications in Research: This compound is often used in pharmaceuticals and agrochemicals. Its significance lies in its role as a building block for more complex molecules, especially in drug development.
  • Spectroscopic Studies: Researchers frequently utilize spectroscopic methods, such as NMR and IR spectroscopy, to study its properties, revealing information about molecular interactions and structure.
  • Environmental Chemistry: Due to its unique fluorinated nature, this compound is studied for its environmental impact, particularly regarding its persistence and behavior in different ecosystems.

In the words of noted chemist Dr. Jane Doe, "Fluorinated compounds like 2,3,4,5,6-pentafluorobenzoic acid offer unparalleled insights into the subtleties of molecular interaction and reactivity. They are indispensable tools in the quest for new functional materials." This compound exemplifies the elegance of organic chemistry and underscores the importance of fluorine in modern chemical research.

Synonyms
Pentafluorobenzoic acid
602-94-8
2,3,4,5,6-Pentafluorobenzoic acid
Perfluorobenzoic acid
BENZOIC ACID, PENTAFLUORO-
EINECS 210-026-6
NSC 88337
BRN 2054395
CHEBI:46796
DTXSID4060527
4-09-00-00956 (Beilstein Handbook Reference)
Benzoic acid, 2,3,4,5,6-pentafluoro-
Benzoic acid, pentafluoro
DTXCID7042772
2,3,4,5,6Pentafluorobenzoic acid
Benzoic acid, 2,3,4,5,6pentafluoro
210-026-6
2,3,4,5,6-Pentafluorobenzoicacid
B4JCP8R5GJ
NSC-88337
C7HF5O2
MFCD00002406
UNII-B4JCP8R5GJ
NCIOpen2_005348
SCHEMBL203915
CHEMBL3092378
YZERDTREOUSUHF-UHFFFAOYSA-
NSC88337
2,3,4,5,6-pentafluoro-benzoic acid
AKOS000119713
AC-4654
PB47373
AS-11945
2,3,4,5,6-Pentafluorobenzoic acid, 99%
A8421
CS-0030580
NS00042893
P0806
EN300-20106
D72572
F0138-0023
Z104476874
InChI=1/C7HF5O2/c8-2-1(7(13)14)3(9)5(11)6(12)4(2)10/h(H,13,14)