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(2,3,4,5,6-pentafluorophenyl)methanol

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Identification
Molecular formula
C7H3F5O
CAS number
774-47-0
IUPAC name
(2,3,4,5,6-pentafluorophenyl)methanol
State
State

The compound is typically in a solid state at room temperature.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
165.00
Boiling point (Kelvin)
438.15
General information
Molecular weight
180.09g/mol
Molar mass
180.0920g/mol
Density
1.6230g/cm3
Appearence

(2,3,4,5,6-pentafluorophenyl)methanol appears as a white to off-white crystalline solid with no distinctive odour.

Comment on solubility

Solubility of (2,3,4,5,6-pentafluorophenyl)methanol

The solubility of (2,3,4,5,6-pentafluorophenyl)methanol can be quite intriguing due to its unique chemical structure. This compound, characterized by its multiple fluorine substitutions on a phenyl ring, influences its solubility properties significantly.

Key Factors Affecting Solubility:

  • Polarity: The presence of the hydroxyl (-OH) group can increase the polarity of the molecule, enabling better solubility in polar solvents, such as water.
  • Hydrogen Bonding: The -OH group can participate in hydrogen bonding, enhancing its interaction with water molecules and other polar solvents.
  • Fluorine Influence: The five fluorine atoms create a significant electronegative pull, which can affect the overall interactions and solubility behavior in organic solvents.

However, it’s important to note that while (2,3,4,5,6-pentafluorophenyl)methanol is expected to be soluble in some polar solvents, it may have limited solubility in nonpolar solvents due to the strong polarity imparted by the hydroxyl group and the bulky fluorinated phenyl group. As a result, the solubility behavior becomes highly dependent on the solvent choice.

In conclusion, the solubility of (2,3,4,5,6-pentafluorophenyl)methanol exhibits a complex interplay of structural characteristics and environmental factors, making it a fascinating subject for further research.

Interesting facts

Interesting Facts About (2,3,4,5,6-pentafluorophenyl)methanol

(2,3,4,5,6-pentafluorophenyl)methanol is a fascinating compound that stands out due to its unique structure and properties. This compound features a benzene ring that is heavily substituted with five fluorine atoms, making it one of the most fluorinated organic compounds. Here are some notable aspects of this intriguing chemical:

  • Fluorine Substitution: The presence of multiple fluorine atoms significantly alters the chemical behavior of the compound. Fluorine's electronegativity enhances both the stability and reactivity of (2,3,4,5,6-pentafluorophenyl)methanol.
  • Applications in Research: This compound is often utilized in scientific research, particularly in the fields of medicinal chemistry and materials science. Its unique properties make it a candidate for developing new pharmaceuticals and advanced materials.
  • Potential in Drug Discovery: The fluorinated structure can lead to improved bioactivity and metabolic stability in drugs, making (2,3,4,5,6-pentafluorophenyl)methanol an interesting subject for drug design projects.
  • Environmental Impact: Understanding the behavior of fluorinated compounds is crucial as they can persist in the environment. Studying (2,3,4,5,6-pentafluorophenyl)methanol can provide insights into how such compounds interact with ecosystems.
  • Mechanistic Studies: Researchers are keen on investigating the mechanisms of various reactions involving this compound, which can yield significant information on reaction kinetics and pathways.

In conclusion, (2,3,4,5,6-pentafluorophenyl)methanol is not just a simple structural compound; it holds vast potential for research and application across multiple disciplines, revealing the profound influence of chemical structure on reactivity and application.

Synonyms
2,3,4,5,6-Pentafluorobenzyl alcohol
440-60-8
Pentafluorobenzyl alcohol
(Perfluorophenyl)methanol
(2,3,4,5,6-Pentafluorophenyl)methanol
(Pentafluorophenyl)methanol
Benzenemethanol, 2,3,4,5,6-pentafluoro-
(Hydroxymethyl)pentafluorobenzene
2,3,4,5,6-Pentafluorobenzenemethanol
FYY8AJK1SP
EINECS 207-126-7
NSC 97003
BRN 2052669
UNII-FYY8AJK1SP
MFCD00004602
NSC-97003
BENZYL ALCOHOL, 2,3,4,5,6-PENTAFLUORO-
CHEBI:44903
DTXSID00196013
2,3,4,5,6-pentafluorobenzylalcohol
PFB
2,3,4,5,6-Pentafluorobenzylic alcohol
(Hydroxymethyl)pentafluorobenzene; 2,3,4,5,6-Pentafluorobenzyl Alcohol;(Pentafluorophenyl)methanol; Pentafluorobenzyl Alcohol; 2,3,4,5,6-pentafluoro-Benzenemethanol
5FBzOH
Maybridge3_000177
SCHEMBL536295
DTXCID10118504
HMS1431I01
NSC97003
BBL011097
CCG-50568
STK802329
AKOS005622588
DB01711
IDI1_011564
AS-14405
PD008483
SY032651
(2,3,4,5,6-pentafluorophenyl)-methanol
(2,3,4,5,6-Pentafluorophenyl)methanol #
DB-001196
CS-0121504
NS00043411
P0849
2,3,4,5,6-Pentafluorobenzyl alcohol, 98%
EN300-226052
Benzenemethanol, 2,3,4,5,6-pentafluoro-(9CI)
SR-01000639936-1
Q27092878
Z431952398
207-126-7