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2,3,5-Trichloropyridin-4-one

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Identification
Molecular formula
C5HCl3NO
CAS number
2529-17-1
IUPAC name
2,3,5-trichloro-1H-pyridin-4-one
State
State

At room temperature, 2,3,5-Trichloropyridin-4-one is a solid.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
315.50
Boiling point (Kelvin)
588.65
General information
Molecular weight
178.43g/mol
Molar mass
178.4260g/mol
Density
1.7879g/cm3
Appearence

2,3,5-Trichloropyridin-4-one typically appears as a white to off-white crystalline solid. It is often noted for its characteristic odor, which is similar to that of related chlorinated pyridine compounds.

Comment on solubility

Solubility of 2,3,5-trichloro-1H-pyridin-4-one

2,3,5-trichloro-1H-pyridin-4-one exhibits a noteworthy solubility profile that can be attributed to its chemical structure and interactions with solvents. This compound is known for its moderate solubility in polar solvents, particularly water and alcohols, due to the presence of both amino and hydroxyl functional groups that can engage in hydrogen bonding.

When considering the solubility characteristics, it is essential to note:

  • Polar solvents: 2,3,5-trichloro-1H-pyridin-4-one dissolves well in solvents like water and methanol.
  • Non-polar solvents: The solubility is significantly reduced in non-polar solvents such as hexane or toluene.
  • Temperature effect: Increased temperature typically enhances the solubility of solids in liquids, making this an important factor during experimental procedures.

In summary, the solubility of 2,3,5-trichloro-1H-pyridin-4-one is influenced by its polarity and interactions with solvents. A comprehensive understanding of its solubility can greatly facilitate its applications in various fields, including pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about 2,3,5-Trichloro-1H-pyridin-4-one

2,3,5-trichloro-1H-pyridin-4-one is a compound that has captured the interest of scientists for its unique properties and potential applications. This intricately structured heterocyclic compound belongs to the class of pyridines, which are known for their versatility in chemical reactions.

Key Features

  • Structural Significance: The presence of three chlorine atoms attached to the pyridine ring significantly impacts its reactivity and stability, making it a point of interest in various synthetic pathways.
  • Biological Activity: Compounds with similar structures have been researched for their biological properties, including potential antimicrobial and antifungal activities, suggesting that 2,3,5-trichloro-1H-pyridin-4-one might exhibit noteworthy pharmacological effects.
  • Role in Synthesis: Its chlorinated structure can serve as a key intermediate in the synthesis of other complex organic molecules, paving the way for further explorations in medicinal chemistry.
  • Environmental Considerations: The stability afforded by chlorine substituents can lead to persistence in environmental contexts, prompting studies on its degradation and environmental impact.

Research Insights

Studies indicate that compounds like 2,3,5-trichloro-1H-pyridin-4-one can act as important building blocks in the creation of agrochemicals and pharmaceuticals. According to a research study, "the diverse reactivity of chlorinated derivatives in organic synthesis often leads to the development of novel compounds with significant therapeutic potential."

As researchers continue to explore this intriguing compound, we may discover even more vital applications and insights into its role within biological systems and synthetic chemistry.

Synonyms
1970-40-7
2,3,5-Trichloropyridin-4-ol
PYRICLOR
2,3,5-Trichloro-4-pyridinol
Daxtron
Pyriclor [ISO]
2,3,5-Trichloro-4-hydroxypyridine
Caswell No. 882G
4-Pyridinol, 2,3,5-trichloro-
Pyrichlor
UNII-68ACR3FCDY
68ACR3FCDY
4-Hydroxy-2,3,5-trichloropyridine
EPA Pesticide Chemical Code 482800
BRN 0383795
DTXSID7042354
1-21-00-00203 (Beilstein Handbook Reference)
m 2901
DTXCID5022354
xtvifvaldytcll-uhfffaoysa-n
2,3,5-trichloro-1H-pyridin-4-one
4-Pyridinol,2,3,5-trichloro-
MFCD01690819
SCHEMBL135431
AKOS006277081
DS-5131
SB52480
DA-19512
CS-0157875
C73749
pyridine, 2,3,5-trichloro-1,4-dihydro-4-oxo-
Q27264233