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2,3,5-Trimethylindole

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Identification
Molecular formula
C11H13N
CAS number
23144-30-5
IUPAC name
2,3,5-trimethyl-1H-indole
State
State

At room temperature, 2,3,5-Trimethylindole is typically a solid due to its crystalline nature, and it will remain stable unless the temperature significantly increases or decreases beyond typical storage conditions.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
171.23g/mol
Molar mass
171.2540g/mol
Density
1.0075g/cm3
Appearence

2,3,5-Trimethylindole is a pale yellow to brownish crystalline solid. It may appear as a powder or in slightly granular form. The compound is typically stable under recommended storage conditions.

Comment on solubility

Solubility of 2,3,5-trimethyl-1H-indole

Understanding the solubility of 2,3,5-trimethyl-1H-indole is essential for its applications in various fields. This compound exhibits qualities that influence its ability to dissolve in different solvents:

  • Polar solvents: 2,3,5-trimethyl-1H-indole tends to have limited solubility in highly polar solvents, such as water, due to its hydrophobic character. The presence of non-polar hydrocarbon groups contributes to this behavior.
  • Non-polar solvents: In contrast, this compound is generally more soluble in non-polar solvents like hexane or benzene, where it can interact favorably with similar non-polar molecules.
  • Organic solvents: It exhibits moderate solubility in organic solvents like ethanol and acetone, which possess both polar and non-polar characteristics, facilitating better interactions with the compound.

In summary, the solubility of 2,3,5-trimethyl-1H-indole can be succinctly characterized as:

  1. Poor in polar solvents.
  2. Better in non-polar solvents.
  3. Moderate in organic solvents.

These solubility traits highlight the importance of considering solvent choice in practical applications of 2,3,5-trimethyl-1H-indole, particularly in the fields of chemistry and pharmaceuticals.

Interesting facts

Interesting Facts about 2,3,5-trimethyl-1H-indole

2,3,5-trimethyl-1H-indole is a fascinating compound that belongs to the class of indoles, widely recognized for their diverse roles in nature and chemistry. Here are some intriguing aspects of this compound:

  • Natural Occurrence: Indoles and their derivatives are often found in a variety of natural sources, including plants, fungi, and even some bacterial species. This makes them significant in the study of biochemistry and natural products.
  • Biological Significance: The indole structure is integral to many biological systems. For example, serotonin, a key neurotransmitter in many organisms, is derived from tryptophan, which contains an indole moiety.
  • Industrial Applications: Compounds like 2,3,5-trimethyl-1H-indole are important in the synthesis of various pharmaceuticals, agrochemicals, and flavoring agents. Their ability to act as intermediates in chemical reactions makes them valuable in organic synthesis.
  • Flavor and Fragrance: This compound has also been studied for its potential applications in the food and fragrance industries due to its pleasant aroma, contributing to the sensory characteristics of many products.
  • Environmental Research: The study of indoles, including 2,3,5-trimethyl-1H-indole, has implications in understanding environmental processes, particularly regarding the degradation of organic matter and the cycling of nutrients.

As with many compounds in the indole family, 2,3,5-trimethyl-1H-indole serves as a reminder of the intricate connections between chemistry, biology, and the environment. Ongoing research continues to unveil its potential in various applications, making it a compound worth exploring further.

Synonyms
2,3,5-Trimethyl-1H-indole
2,3,5-Trimethylindole
1H-Indole, 2,3,5-trimethyl-
INDOLE, 2,3,5-TRIMETHYL-
BRN 0118761
G0TZ55R5R5
UNII-G0TZ55R5R5
DTXSID60175561
5-20-07-00143 (Beilstein Handbook Reference)
RefChem:81411
DTXCID5098052
HOFNMMIHFZBKPW-UHFFFAOYSA-N
21296-92-4
SCHEMBL13174592
SCHEMBL30547023
2,3,5-Trimethyl-1H-indole #
SBB044892
STK026306
AKOS000275068
AC-26883
DB-355093
H37866
Q27278496