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Hexahydropyrrolizine

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Identification
Molecular formula
C8H15N
CAS number
5194-55-4
IUPAC name
2,3,5,6,7,8-hexahydro-1H-pyrrolizine
State
State

Hexahydropyrrolizine is a liquid at room temperature. As an organic compound, it features nitrogen within a bicyclic structure.

Melting point (Celsius)
-50.00
Melting point (Kelvin)
223.15
Boiling point (Celsius)
190.50
Boiling point (Kelvin)
463.65
General information
Molecular weight
111.21g/mol
Molar mass
111.1910g/mol
Density
0.9540g/cm3
Appearence

Hexahydropyrrolizine typically appears as a colorless liquid. It is a heterocyclic compound, which can exhibit slight yellowish coloration due to impurities upon standing or exposure over time.

Comment on solubility

Solubility of 2,3,5,6,7,8-hexahydro-1H-pyrrolizine

The solubility of 2,3,5,6,7,8-hexahydro-1H-pyrrolizine, a bicyclic organic compound, can be a nuanced aspect to understand. Here are some key points to consider:

  • Solvent Interaction: This compound's solubility is influenced by its molecular structure, which can interact variably with different solvents.
  • Polarity: The presence of saturated rings generally suggests lower polarity, which often relates to solubility in non-polar solvents such as alkanes or ethers.
  • Temperature Dependency: As with many compounds, increasing temperature may enhance solubility, particularly in organic solvents.
  • Applications: Knowing its solubility is crucial for applications in pharmaceutical formulations, where solubility can directly affect bioavailability.

In summary, while specific solubility data for 2,3,5,6,7,8-hexahydro-1H-pyrrolizine may not be readily available, understanding its potential solubility behaviors can be extrapolated from its chemical features and the nature of potential solvents.

Interesting facts

Interesting Facts about 2,3,5,6,7,8-Hexahydro-1H-Pyrrolizine

2,3,5,6,7,8-hexahydro-1H-pyrrolizine is a fascinating compound with a unique structure and interesting properties. As a bicyclic amine, it belongs to a class of compounds known for their presence in various natural products and synthetic applications. Here are some noteworthy aspects:

  • Structural Characteristics: This compound features a bicyclic framework, which contributes to its stability and reactivity. Its structure allows for potential interactions with biological systems, making it a point of interest in medicinal chemistry.
  • Biological Relevance: Pyrrolizidine alkaloids, which are derived from compounds like 2,3,5,6,7,8-hexahydro-1H-pyrrolizine, exhibit a range of biological activities, including anti-inflammatory and antimicrobial effects. Some studies suggest that these compounds could potentially be developed into new therapeutic agents.
  • Applications in Synthesis: Due to its unique ring structure, 2,3,5,6,7,8-hexahydro-1H-pyrrolizine can act as a building block in organic synthesis. Chemists often explore its use as an intermediate in constructing more complex heterocyclic compounds.
  • Research Potential: The exploration of this compound can lead to insights into its behavior in various chemical reactions, such as cyclization and functionalization. This makes it a valuable subject for students and professionals studying organic chemistry.

With its intriguing structure and potential applications, 2,3,5,6,7,8-hexahydro-1H-pyrrolizine exemplifies the rich interplay between chemical structure and biological function. It serves as a reminder that the world of chemistry is filled with possibilities just waiting to be explored!

Synonyms
PYRROLIZIDINE
643-20-9
Hexahydropyrrolizine
Hexahydro-1H-pyrrolizine
1H-Pyrrolizine, hexahydro-
1-Azabicyclo(3.3.0)octane
2,3,5,6,7,8-hexahydro-1H-pyrrolizine
1-Azabicyclo[3.3.0]octane
UNII-U81KWZ2JKN
U81KWZ2JKN
HSDB 4300
NSC 90874
NSC-90874
PYRROLIZIDINE [HSDB]
CHEBI:64950
DTXSID00214524
NSC-145060
1HPyrrolizine, hexahydro
1Azabicyclo(3.3.0)octane
DTXCID30137015
1H-Pyrrolizine, hexahydro-(8CI)
1H-Pyrrolizine, hexahydro-(8CI)(9CI)
613-574-8
adrdexbbjtucnd-uhfffaoysa-n
hexahydro-pyrrolizine
MFCD22200264
Hexahydro-1H-pyrrolizine #
SCHEMBL35282
NSC90874
1,2,3,4,5,6,7,8-octahydro-pyrrolizine
NS00035667
Q1078442