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Stepholidine

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Identification
Molecular formula
C20H25NO5
CAS number
15301-48-7
IUPAC name
2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol
State
State

At room temperature, stepholidine is generally found in a solid state. It maintains its integrity under standard laboratory conditions without significant volatilization, making it practical for handling and storage at ambient temperature.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
515.15
Boiling point (Kelvin)
788.30
General information
Molecular weight
355.42g/mol
Molar mass
355.4150g/mol
Density
1.3200g/cm3
Appearence

Stepholidine typically appears as a crystalline solid. It can have a color ranging from white to off-white or pale yellow depending on purity and specific preparation methods. The texture is usually fine, with a powdery to slightly granular consistency based on how it's processed for usage.

Comment on solubility

Solubility of 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol

The solubility of 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol can be quite intricate due to its complex structure and multiple functional groups. Here are some important considerations regarding its solubility:

  • Polarity: The presence of methoxy groups generally enhances water solubility, but the overall polarity of the molecule must be assessed, as the extensive aromatic nature may limit solubility in polar solvents.
  • Solvent Choice: This compound may exhibit better solubility in organic solvents such as methanol, ethanol, or dichloromethane rather than in water.
  • Hydrogen Bonding: The hydroxyl group may engage in hydrogen bonding, which can affect solubility characteristics, particularly in polar solvents.
  • Temperature Effects: Typically, an increase in temperature will increase solubility, which is something to consider for practical applications.

In summary, while the solubility of this compound largely depends on its specific interactions with solvents, the general trend is that it may be more soluble in polar organic solvents compared to aqueous solutions. Understanding these solubility characteristics is essential for applications in synthesis and formulation.

Interesting facts

Interesting Facts about 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol

The compound 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-1-ol is a fascinating member of the isoquinoline family. These types of compounds are notable for their diversity in biological activities and structural complexity. Here are some intriguing facts about this particular molecule:

  • Structure and Complexity: The unique structure includes multiple methoxy groups which significantly influence the compound's reactivity and interaction with biological systems.
  • Biological Significance: Isoquinoline derivatives have been extensively studied for their potential pharmacological properties, including anti-cancer, anti-inflammatory, and neuroprotective effects.
  • Synthetic Challenges: The synthesis of such polyfunctionalized compounds can be challenging due to the need for selective functionalization and the control of stereochemistry during the synthetic process.
  • Potential Applications: Researchers are investigating this compound for its potential use in drug discovery and developing treatments for various diseases.

As a member of the chemically rich world of alkaloids, compounds like this one reflecting nature’s ingenuity and serving as a source of inspiration for medicinal chemistry. Understanding the properties and functionalities of such compounds can pave the way for new therapeutic strategies.

In the words of a famous chemist, "Chemistry is the study of transformation," and this molecule’s complex structure exemplifies that transformation at the molecular level.

Synonyms
Capauridin
Capauridine
478-15-9
MLS002920137
13aalpha-Berbin-1-ol, 2,3,9,10-tetramethoxy- (8CI)
Capaurine, (+-)-
NSC 132059
Capaurine, dl-
BERBIN-1-OL, 2,3,9,10-TETRAMETHOXY-, DL-
(.+-.)-Capaurine
Capaurine, (.+-.)-
SCHEMBL679768
NSC132059
NSC404532
NSC-132059
NSC-404532
6H-Dibenzo(a,g)quinolizin-1-ol, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (+-)-
SMR001797734
Berbin-1-ol,3,9,10-tetramethoxy-, dl-
13a.alpha.-Berbin-1-ol,3,9,10-tetramethoxy-
Berbin-1-ol,3,9,10-tetramethoxy-, (.+-.)-
WLN: T D6 B666 KN&TT&J GO1 HO1 PO1 QO1 RQ
6H-Dibenzo[a, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (.+-.)-
6H-Dibenzo[a, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (S)-