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Mitoxantrone

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Identification
Molecular formula
C22H28N4O6
CAS number
65271-80-9
IUPAC name
24-[(9,10-dihydroxy-1-anthryl)imino]-16-azaoctacyclo[18.10.2.02,15.05,14.07,12.017,31.021,26.028,32]dotriaconta-1,3,5(14),7,9,11,15,17(31),18,20,22,25,28(32),29-tetradecaene-6,13,27-trione
State
State

At room temperature, Mitoxantrone is typically a solid. In pharmaceutical formulations, however, it is often stored as a liquid solution for intravenous injection.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
444.44g/mol
Molar mass
444.4390g/mol
Density
1.3540g/cm3
Appearence

Mitoxantrone is a synthetic antineoplastic anthracenedione that appears as a dark blue crystalline powder. It is typically supplied as a dark blue solution when formulated for injection. In its crystalline form, it is very dark and appears almost black under certain lighting conditions.

Comment on solubility

Solubility of 24-[(9,10-dihydroxy-1-anthryl)imino]-16-azaoctacyclo[18.10.2.02,15.05,14.07,12.017,31.021,26.028,32]dotriaconta-1,3,5(14),7,9,11,15,17(31),18,20,22,25,28(32),29-tetradecaene-6,13,27-trione

The solubility of 24-[(9,10-dihydroxy-1-anthryl)imino]-16-azaoctacyclo[18.10.2.02,15.05,14.07,12.017,31.021,26.028,32]dotriaconta-1,3,5(14),7,9,11,15,17(31),18,20,22,25,28(32),29-tetradecaene-6,13,27-trione can be characterized as follows:

  • Solvent Compatibility: The compound is expected to have varying solubility in different solvents.
  • Polar vs Nonpolar: Given the presence of hydroxyl groups, it may show better solubility in polar solvents such as methanol or ethanol compared to nonpolar solvents.
  • Temperature Influence: Solubility might increase with temperature; thus heating the solvent could enhance dissolving capacity.
  • Concentration Effects: At higher concentrations, the solubility can lead to saturation, potentially affecting the stability of solutions.
  • Crystal Formations: The compound's complex structure may also affect the arrangement of molecules, influencing solubility behavior significantly.

Overall, specific experimental methods should be conducted to determine precise solubility values in various solvents under varying conditions. Understanding the solubility properties of this intricate molecule is vital for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 24-[(9,10-Dihydroxy-1-anthryl)imino]-16-azaoctacyclo[18.10.2.02,15.05,14.07,12.017,31.021,26.028,32]dotriaconta-1,3,5(14),7,9,11,15,17(31),18,20,22,25,28(32),29-tetradecaene-6,13,27-trione

This compound is an intriguing example of a complex organic molecule that showcases the beauty of structural diversity in chemical compounds. Here are some notable points that highlight its significance:

  • Complexity of Structure: The name of this compound reveals its intricate arrangement of rings and functional groups, making it a challenge for chemists to synthesize and characterize.
  • Anthracene Derivative: It features an anthracene backbone, known for its use in organic electronics, including organic semiconductors and light-emitting diodes, hinting at potential applications in the field of materials science.
  • Biological Applications: Compounds like this one, particularly those with hydroxyl and azo groups, have sparked interest in medicinal chemistry as they might exhibit unique biological activities or serve as dyes or indicators in biological systems.
  • Mechanistic Insights: This compound can provide valuable insights into reaction mechanisms and molecular interactions, particularly how large polycyclic structures behave in various chemical environments.
  • Research Interest: Due to its complex structure and potential applications, it is often the subject of theoretical studies and computational chemistry, where researchers explore its properties and predict behavior.

Overall, the exploration of such compounds goes beyond their chemical formula; it opens avenues for innovation in both fundamental research and practical applications. As a scientist or student, understanding the intricacies of this compound can inspire future discoveries in chemistry.