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Triclosan

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Identification
Molecular formula
C12H7Cl3O2
CAS number
3380-34-5
IUPAC name
2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol
State
State

Triclosan is typically in a solid state at room temperature, appearing as a white crystalline powder.

Melting point (Celsius)
56.00
Melting point (Kelvin)
329.00
Boiling point (Celsius)
120.00
Boiling point (Kelvin)
393.00
General information
Molecular weight
289.55g/mol
Molar mass
289.5450g/mol
Density
1.4900g/cm3
Appearence

Triclosan appears as a white crystalline powder. It is odorless and its fine crystals make it suitable for use in various formulations, such as in personal care products.

Comment on solubility

Solubility of 2,4-Dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol

2,4-Dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol, often referred to as an effective phenolic compound, exhibits unique solubility characteristics that are critical to its applications. Understanding its solubility can help predict its behavior in various environments:

  • Solvent Compatibility: This compound is generally more soluble in organic solvents such as ethanol, acetone, and chloroform, while showing limited solubility in water. This can be attributed to its hydrophobic structural components.
  • Temperature Influence: Increased temperature often enhances the solubility of phenolic compounds in organic solvents. However, the solubility behavior in water at different temperatures may not follow the same trend.
  • pH Factors: The presence of hydroxyl groups in the molecular structure can lead to variable solubility depending on the pH of the solvent. In alkaline conditions, the potential for ionization can improve water solubility.

In summary, while 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol has limited solubility in aqueous environments, it demonstrates better solubility in organic solvents under appropriate conditions. This solubility profile is essential for its application in various chemical processes and formulations.

Interesting facts

Interesting Facts About 2,4-Dichloro-6-[(3,5-Dichloro-2-Hydroxy-Phenyl)methyl]Phenol

2,4-Dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol, often referred to in scientific literature as a complex organic compound, possesses unique properties and applications that make it noteworthy in the realm of chemistry.

Key Highlights:

  • Antimicrobial Properties: This compound is particularly recognized for its effectiveness as an antimicrobial agent. It has been studied extensively for use in biomedical applications where microbial growth inhibition is crucial.
  • Pesticidal Uses: Given its structure, it also finds utility in agricultural settings, acting as a pesticide. Its dual-action structure allows it to target various pests, thereby protecting vital crops.
  • Analytical Chemistry: The compound serves as a vital subject in analytical chemistry for developing methods to detect and quantify chlorinated compounds in environmental samples.
  • Structure-Activity Relationship (SAR): The presence of multiple chlorine substituents and a hydroxyl group makes it an interesting candidate for SAR studies, aiding researchers in understanding how changes in molecular structure affect biological activity.

Moreover, the synthesis of this compound involves intricate organic reactions that showcase the beauty and complexity of organic chemistry. Researchers and students alike appreciate the challenges presented in synthesizing such a chlorinated phenolic compound, which can lead to numerous synthetic pathways and mechanisms of reaction.

As a pivotal compound in both medicinal chemistry and environmental sciences, 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol continues to be a focus of ongoing research, demonstrating the dynamic nature of chemical compounds in both theoretical and practical applications.

Synonyms
TETRACHLOROPHENE
1940-43-8
2,2'-Methylenebis(4,6-dichlorophenol)
Bis(2-hydroxy-3,5-dichlorophenyl)methane
F2TLR1878A
2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)methyl]phenol
NSC-9873
NSC-14796
NSC-402193
2,6-dichlorophenol)
WLN: QR BG DG F1R BQ CG EG
2,3',5,5'-tetrachlorodiphenylmethane
NSC 9873
Phenol,2'-methylenebis[4,6-dichloro-
EINECS 217-720-8
NSC 14796
NSC 402193
BRN 2625381
UNII-F2TLR1878A
AI3-02371
Phenol, 2,2'-methylenebis(4,6-dichloro-
2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylmethane
SCHEMBL67608
CHEMBL33846
DTXSID1042449
NSC9873
KUC112935N
NSC14796
NSC402193
6,6'-methylenebis(2,4-dichlorophenol)
2,2'-Methyl-enebis[4,6-dichlorophenol]
KSC-336-006-1
DB-044844
NS00026323
2,2'- Dioxy-3,5,3',5'-tetrachlordiphenylmethan
Q27277553
2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)methyl]phenol