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Lerimazoline

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Identification
Molecular formula
C17H12Cl2N2O
CAS number
968-81-0
IUPAC name
(2,4-dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol
State
State

At room temperature, Lerimazoline is a solid. It does not have a known distinctive odor and is highly stable under normal conditions.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
479.30
Boiling point (Kelvin)
752.45
General information
Molecular weight
336.20g/mol
Molar mass
336.1570g/mol
Density
1.3500g/cm3
Appearence

The compound typically appears as a crystalline solid. It is often white to off-white in coloration. Since it is a solid at room temperature, it can be found in a powdery or crystalline form.

Comment on solubility

Solubility of (2,4-Dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol

The solubility of (2,4-Dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol can be influenced by various factors, including its molecular structure, temperature, and the solvent used. When considering solubility, it is essential to evaluate:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents like water, whereas a predominantly non-polar structure would favor solubility in organic solvents.
  • Hydrogen Bonding: This compound potentially participates in hydrogen bonding due to the hydroxyl (−OH) group, which can increase its solubility in certain solvents.
  • Temperature: Solubility can vary with temperature changes, often increasing with higher temperatures for most solutes.

However, specific solubility data for this compound might be limited. It is crucial to consult empirical data or perform laboratory solubility tests for accurate insights. In general, one might observe that:

  • It could be moderately soluble in polar organic solvents.
  • Its solubility in water may be low due to the overall hydrophobic character imparted by the aromatic rings.

In summary, while the theoretical understanding gives us a good basis for predicting solubility, concrete measurements are paramount for precise applications. Remember, *the right solvent is the key to achieving optimal solubility*!

Interesting facts

Interesting Facts about (2,4-dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol

(2,4-dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol is a fascinating compound that has garnered attention in the realm of medicinal chemistry. Here are some compelling aspects worth noting:

  • Medicinal Potential: This compound is known for its role in various pharmaceutical applications. Its chemical structure allows for interactions with biological targets, making it a candidate for therapeutic development.
  • Structure and Substitution: The presence of two chlorine atoms at the 2 and 4 positions of the phenyl ring can influence the compound's reactivity and biological activity. Chlorinated aromatic compounds are often found in many fields such as agriculture and medicinal chemistry.
  • Pyrimidine Core: The pyrimidine ring, a fundamental structure in biochemistry, is centrally located in this compound. Compounds containing pyrimidine are frequently studied for their role in nucleic acid metabolism.
  • Potential Applications: Due to its unique structure, (2,4-dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol might exhibit properties such as anti-inflammatory or antimicrobial effects, making it a subject of interest for drug discovery.
  • Research Efforts: Scientists continuously explore this compound to enhance its biological efficacy and reduce potential side effects. This process often involves synthetic modifications and biological testing.

In conclusion, the complex structure of (2,4-dichlorophenyl)-phenyl-pyrimidin-5-yl-methanol not only showcases the intricate beauty of chemical compounds but also highlights the ongoing quest for new therapeutic agents in the field of medicinal chemistry. As researchers continue to unveil its properties, we can look forward to greater insights and applications arising from this intriguing compound.

Synonyms
TRIARIMOL
26766-27-8
EL-273
15108BI2HR
NSC-232672
DTXSID7042483
alpha-(2,4-Dichlorophenyl)-alpha-phenyl-5-pyrimidinemethanol
CHEBI:82074
5-Pyrimidinemethanol, alpha-(2,4-dichlorophenyl)-alpha-phenyl-
RefChem:899050
DTXCID5022483
(2,4-dichlorophenyl)-phenyl-pyrimidin-5-ylmethanol
EL 273
.alpha.-(2,4-Dichlorophenyl)-.alpha.-phenyl-5-pyrimidinemethanol
5-Pyrimidinemethanol, .alpha.-(2,4-dichlorophenyl)-.alpha.-phenyl-
Triarimol [ANSI]
Caswell No. 861A
Triarimol [ANSI:ISO]
EPA Pesticide Chemical Code 361200
NSC 232672
BRN 0756381
UNII-15108BI2HR
TRIARIMOL [ISO]
5-23-12-00538 (Beilstein Handbook Reference)
SCHEMBL149650
CHEMBL407132
SCHEMBL29516996
TRIARIMO, (+/-)-
CHEBI:133643
BDBM50375306
NSC232672
NS00123645
C18932
(2,4-Dichlorophenyl)(phenyl)5-pyrimidinylmethanol #
Q27155728
5-Pyrimidinemethanol,4-dichlorophenyl)-.alpha.-phenyl-
(2,4-DICHLOROPHENYL)-ALPHA-PHENYL-5-PYRIMIDINEMETHANOL, ALPHA