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2,4-Difluoro-6-nitroaniline

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Identification
Molecular formula
C6H4F2N2O2
CAS number
395-28-8
IUPAC name
2,4-difluoro-6-nitro-aniline
State
State

At room temperature, 2,4-Difluoro-6-nitroaniline is in a solid state, presenting as a crystalline yellow solid, due to its molecular structure and physical properties.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
228.00
Boiling point (Kelvin)
501.15
General information
Molecular weight
174.12g/mol
Molar mass
174.1160g/mol
Density
1.5390g/cm3
Appearence

2,4-Difluoro-6-nitroaniline typically appears as a yellow crystalline solid. It is considered stable under normal conditions and is usually handled in its solid form.

Comment on solubility

Solubility of 2,4-Difluoro-6-nitro-aniline

2,4-difluoro-6-nitro-aniline, a compound with the chemical formula C7H6F2N2O2, exhibits unique solubility characteristics that are quite interesting to explore. The solubility of this compound can be influenced by several factors, including:

  • Polarity: Due to the presence of both nitro (-NO2) and amino (-NH2) groups, the compound has a polar character, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The amino group allows for potential hydrogen bonding with solvents like water, promoting solubility. However, the presence of halogen atoms may somewhat complicate this interaction.
  • pH Sensitivity: The solubility might vary significantly with changes in pH, particularly in aqueous solutions, due to the ionization of the amino group at different pH levels.

Generally, 2,4-difluoro-6-nitro-aniline is expected to show moderate solubility in polar organic solvents, whereas its solubility in water may be limited. It is essential to note that the actual solubility can be affected by temperature and the presence of other solutes.

In summary, while one might note the presence of functional groups that typically promote solubility, the unique combination of electron-withdrawing and donating groups in 2,4-difluoro-6-nitro-aniline leads to a more nuanced solubility behavior that merits further investigation.

Interesting facts

Interesting Facts about 2,4-Difluoro-6-nitro-aniline

2,4-Difluoro-6-nitro-aniline is a fascinating compound that belongs to the class of aromatic amines, which are known for their diverse applications in various fields such as pharmaceuticals, agrochemicals, and dyes. Here are some intriguing aspects of this compound:

  • Structural Unique Features: This compound contains both fluorine and nitro functional groups that significantly influence its reactivity and properties. The presence of fluorine often enhances the compound's biological activity.
  • Biological Activity: Compounds with nitro groups, like 2,4-difluoro-6-nitro-aniline, can exhibit interesting pharmacological properties. Some nitroanilines have shown potential as *anti-inflammatory* agents, making them important in medicinal chemistry.
  • Industrial Significance: This compound can be utilized in the synthesis of other complex organic molecules. Its ability to act as a building block in organic synthesis highlights its importance in the development of new materials and compounds.
  • Research Applications: Investigations around compounds like this one can lead to innovations in areas such as *drug development*, where understanding the structure-activity relationships can help in designing more effective therapeutic agents.
  • Environmental Impact: The presence of fluorinated compounds in environmental matrices has raised concerns about their persistence and bioaccumulation. Understanding their environmental chemistry is crucial for assessing their safety and potential regulations regarding their use.

In conclusion, 2,4-difluoro-6-nitro-aniline serves as a great example of how a seemingly simple compound can open doors into *multiple realms of research and application*. Its features not only establish its significance in the laboratory but also demonstrate the intricate connections within the vast field of chemistry.

Synonyms
2,4-Difluoro-6-nitroaniline
364-30-7
ANILINE, 2,4-DIFLUORO-6-NITRO-
Benzenamine, 2,4-difluoro-6-nitro-
UM69Q7VNX7
NSC 81335
BRN 2722853
MFCD00034058
NSC-81335
2,4-difluoro-6-nitrobenzenamine
DTXSID90189919
(2,4-DIFLUORO-6-NITROPHENYL)AMINE
EN300-102827
2-Amino-3,5-difluoronitrobenzene
NSC81335
UNII-UM69Q7VNX7
WLN: ZR BF DF FNW
NCIOpen2_000912
Aniline,4-difluoro-6-nitro-
SCHEMBL602423
DTXCID00112410
WPEUQAOOZXFRKZ-UHFFFAOYSA-N
BDBM625961
BBL101665
STL555461
AKOS006227837
AC-9656
DS-14273
SY018633
DB-030789
CS-0146875
D4733
609-244-8