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Trolamine Salicylate

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Identification
Molecular formula
C20H39NO3
CAS number
51144-07-7
IUPAC name
2,4-dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylnorbornan-2-yl)butanamide
State
State

The compound is generally found in a solid state at room temperature but can also be in a viscous liquid form when in its pure state.

Melting point (Celsius)
15.00
Melting point (Kelvin)
288.15
Boiling point (Celsius)
336.40
Boiling point (Kelvin)
609.60
General information
Molecular weight
375.58g/mol
Molar mass
375.5750g/mol
Density
1.0045g/cm3
Appearence

The compound typically appears as a white or off-white powder. It might crystallize depending on the purity and storage conditions. In a formulated product, especially in creams or lotions, it is usually dissolved, contributing minimally to the appearance which is mostly dictated by other ingredients.

Comment on solubility

Solubility of 2,4-dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylnorbornan-2-yl)butanamide

The solubility of **2,4-dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylnorbornan-2-yl)butanamide** can be influenced by several factors, including its molecular structure and functional groups. Understanding its solubility characteristics is crucial for numerous applications in chemistry and pharmaceuticals.

Key Points about Solubility:

  • Hydrophilicity: The presence of hydroxyl groups (-OH) often enhances water solubility due to hydrogen bonding.
  • Hydrophobicity: The bulky trimethyl and norbornane groups can contribute to hydrophobic interactions, potentially decreasing water solubility.
  • Solvent Effects: Solubility may vary significantly in different solvents. It may be more soluble in organic solvents compared to aqueous solutions.
  • pH Influence: Changes in pH can affect the ionization of functional groups, altering solubility. The zwitterionic nature can emerge at certain pH levels.

In conclusion, while **2,4-dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylnorbornan-2-yl)butanamide** may possess moderate solubility in water due to its hydroxyl groups, its hydrophobic characteristics suggest a tendency to be more soluble in organic solvents. As with many chemical compounds, the interplay of various factors determines the solubility landscape, and careful evaluation through experimental methods is necessary to fully ascertain its solubility profile.

Interesting facts

Interesting Facts about 2,4-Dihydroxy-3,3-Dimethyl-N-(1,7,7-Trimethylnorbornan-2-yl)butanamide

This compound is a fascinating example of how complex organic molecules can be tailored for specific properties and applications. Here are some intriguing aspects about it:

  • Structural Complexity: The compound features a unique arrangement of functional groups, including two hydroxy groups, which contribute to its chemical reactivity and potential biological activity.
  • Application in Pharmaceuticals: Due to its structure, 2,4-dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylnorbornan-2-yl)butanamide may have implications in drug design; compounds with hydroxy groups often engage in hydrogen bonding, which can enhance interactions with biological targets.
  • Synthetic Challenge: The synthesis of this compound likely involves intricate synthetic pathways, showcasing the creativity required in modern organic chemistry to construct such elaborate molecules.
  • Chirality and Isomerism: The presence of multiple stereogenic centers renders this compound chiral, which is a crucial aspect in medicinal chemistry, as different enantiomers can have different biological effects.
  • Potential Natural Occurrence: The framework of the compound, reminiscent of terpenoids, suggests that it may have natural analogs or could inspire the discovery of new natural products in the realm of organic molecules.

Overall, the examination of such compounds not only enriches our understanding of molecular diversity but also reinforces the significance of synthetic chemistry in developing new materials and therapeutic agents. As one researcher aptly put it, "Every complex molecule tells a story of nature's creativity shaped by the principles of chemistry."


Synonyms
(+-)-endo-N-(2-Bornyl)-2,4-dihydroxy-3,3-dimethylbutyramide
24629-81-0
BUTYRAMIDE, N-(2-BORNYL)-2,4-DIHYDROXY-3,3-DIMETHYL-, endo-(+-)-
RefChem:331194
DTXSID30947550
2,4-Dihydroxy-3,3-dimethyl-N-(1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)butanimidic acid