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2,4,5-Trichlorobenzenesulfonyl chloride

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Identification
Molecular formula
C6H2Cl3O2S
CAS number
84417-72-3
IUPAC name
2,4,5-trichlorobenzenesulfonyl chloride
State
State

At room temperature, 2,4,5-Trichlorobenzenesulfonyl chloride is typically encountered as a solid. It is known to be relatively stable in this state under standard conditions of temperature and pressure.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.15
General information
Molecular weight
276.49g/mol
Molar mass
276.4900g/mol
Density
1.6370g/cm3
Appearence

2,4,5-Trichlorobenzenesulfonyl chloride is generally an off-white to pale yellow solid. It may appear as crystalline powder or chunks depending on its purity and handling. It has a distinctive chemical appearance typical of aromatic sulfonyl chlorides.

Comment on solubility

Solubility of 2,4,5-trichlorobenzenesulfonyl chloride

2,4,5-trichlorobenzenesulfonyl chloride, often referred to in shorthand as TCBSC, exhibits unique solubility characteristics that are important for its applications in various chemical reactions.

When discussing the solubility of this compound, several key points should be highlighted:

  • Solvent Dependence: TCBSC is typically soluble in organic solvents such as acetone, dichloromethane, and certain alcohols. However, it demonstrates low solubility in polar solvents like water.
  • Hydrophobic Characteristics: The presence of multiple Cl (chlorine) atoms contributes to its hydrophobic nature, making it resistant to dissolution in aqueous environments.
  • Temperature Effects: Solubility can also be influenced by temperature; generally, increasing temperature leads to higher solubility in organic solvents.
  • Practical Implications: Its solubility profile is essential for its use in synthesis and as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes.

In conclusion, while 2,4,5-trichlorobenzenesulfonyl chloride is soluble in a variety of organic solvents, understanding its low solubility in water and the factors that affect this property is crucial for effective handling and application in chemical processes. As noted by researchers, “The solubility characteristics play a pivotal role in the reactivity and stability of the compound.”

Interesting facts

Interesting Facts about 2,4,5-Trichlorobenzenesulfonyl Chloride

2,4,5-Trichlorobenzenesulfonyl chloride is a fascinating chemical compound that plays a significant role in various chemical processes and applications. Here are some intriguing insights:

  • Structure and Reactivity: This compound has a unique structure characterized by the presence of both a sulfonyl chloride and multiple chlorine substituents on a benzene ring. This configuration enhances its reactivity, making it a valuable intermediate in organic synthesis.
  • Key Applications: 2,4,5-trichlorobenzenesulfonyl chloride serves as a versatile reagent in the preparation of sulfonamide derivatives and other complex organic molecules. Its ability to effectively introduce the sulfonyl group into various substrates makes it a favored compound among chemists.
  • Role in Pharmaceuticals: This compound is frequently utilized in pharmaceutical chemistry. By modifying its structure, researchers can design and synthesize novel drugs with desired biological activities.
  • Environmental Impact: Due to the presence of chlorine atoms, there is ongoing research to assess the environmental impact of its degradation products. Understanding its behavior in the environment helps in developing safer chemical practices.
  • Safety Considerations: As with many chlorinated compounds, 2,4,5-trichlorobenzenesulfonyl chloride can be hazardous. It is essential for chemists to understand and implement safety protocols while handling this substance to mitigate any potential health risks.

"Chemistry is the study of transformation, and the synthesis involving 2,4,5-trichlorobenzenesulfonyl chloride exemplifies this by allowing the creation of new compounds with exciting properties."

In summary, 2,4,5-trichlorobenzenesulfonyl chloride not only holds academic interest but also has practical significance in the field of synthetic chemistry, showcasing the interconnectedness of chemical knowledge and real-world application.

Synonyms
2,4,5-TRICHLOROBENZENESULFONYL CHLORIDE
15945-07-0
Benzenesulfonyl chloride, 2,4,5-trichloro-
UNII-7GD5283XIX
2,4,5-trichlorophenylsulfonyl chloride
7GD5283XIX
EINECS 240-079-0
NSC 26958
NSC-26958
DTXSID1065974
DTXCID9035129
240-079-0
WNVVRCKTQSCPAC-UHFFFAOYSA-N
2,4,5-trichlorobenzene-1-sulfonyl chloride
MFCD00007428
NSC26958
2,4,5-Trichlorobenzenesulphonyl chloride
SCHEMBL534192
orb1741354
SCHEMBL30161536
2,4,5trichlorophenylsulfonylchloride
BBL104377
SBB066468
STL558635
2,5-Trichlorobenzenesulfonyl chloride
chloro(2,4,5-trichlorophenyl)sulfone
AKOS000149063
AKOS024319647
2,4,5-trichlorobenzenesulphonylchloride
Benzenesulfonyl chloride,4,5-trichloro-
MS-20051
SY048901
2,4,5-trichlorobenzene-1-sulfonylchloride
B0247
CS-0157844
NS00025189
ST50411797
2,4,5-Trichlorobenzenesulfonyl chloride, 95%
D88617
EN300-270952
Q27268243