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2,4,5-Trimethoxybenzaldehyde

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Identification
Molecular formula
C10H12O4
CAS number
4460-86-0
IUPAC name
2,4,5-trimethoxybenzaldehyde
State
State

At room temperature, 2,4,5-trimethoxybenzaldehyde is in a solid state, forming crystalline structures.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
161.00
Boiling point (Kelvin)
434.15
General information
Molecular weight
196.20g/mol
Molar mass
196.2010g/mol
Density
1.1950g/cm3
Appearence

2,4,5-Trimethoxybenzaldehyde typically appears as a white to off-white crystalline powder. Its solid-state nature and crystalline structure can be characterized by its sheen and particle form.

Comment on solubility

Solubility of 2,4,5-trimethoxybenzaldehyde

2,4,5-trimethoxybenzaldehyde, with its complex structure, exhibits specific solubility characteristics that are important to note. This compound, which features three methoxy groups attached to a benzaldehyde unit, typically shows moderate solubility in various organic solvents.

Solubility Characteristics

  • Polar Solvents: It is generally soluble in polar organic solvents such as ethanol and methanol due to the presence of the methoxy groups, which can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane may be limited, as the aromatic nature and the steric hindrance from the methoxy groups reduce interactions with non-polar molecules.
  • Water: This compound has very low solubility in water, attributed to its hydrophobic benzene ring structure.

In practice, it is crucial to consider the solubilizing environments for this compound. As a general guideline, it can be said that "the more polar the solvent, the better the solubility of 2,4,5-trimethoxybenzaldehyde." Understanding the solubility profile not only aids in various applications but also influences reaction conditions and formulation strategies in synthetic chemistry.

Interesting facts

Interesting Facts About 2,4,5-Trimethoxybenzaldehyde

2,4,5-trimethoxybenzaldehyde is an intriguing compound with various applications and characteristics that make it a subject of interest in the scientific community. Here are some engaging facts about this aromatic aldehyde:

  • Natural Occurrence: This compound is often derived from natural sources, particularly found in certain plant species, where it can contribute to their fragrance and flavor profile.
  • Flavor and Fragrance: Due to its pleasant aromatic properties, 2,4,5-trimethoxybenzaldehyde is widely utilized in the flavor and fragrance industry. It is used in creating synthetic versions of vanilla and other sweet scents.
  • Precursor in Synthesis: It serves as a key starting material in the synthesis of various complex organic compounds, paving the way for researchers developing new pharmaceuticals and agrochemicals.
  • Biological Activity: Some studies have indicated potential biological activities associated with compounds structurally related to 2,4,5-trimethoxybenzaldehyde, including antioxidant and anti-inflammatory properties.
  • Research Interest: The compound has garnered attention in academia for its role in studying molecular interactions and reactions due to its aldehyde functional group, making it a valuable asset in organic chemistry research.

Furthermore, it's fascinating to note how aromatic aldehydes like 2,4,5-trimethoxybenzaldehyde play critical roles beyond flavoring, influencing the aromatic compounds found in nature and their synthetic counterparts. As quoted by one researcher, "A small change in molecular structure can lead to vast variations in character and utility in the world of organic compounds." This highlights the complexity and vast potential of studying such compounds in-depth.

In summary, 2,4,5-trimethoxybenzaldehyde is not just a simple organic molecule; it encapsulates the essence of chemical versatility, bridging the gap between natural compounds and synthetic chemistry.

Synonyms
2,4,5-TRIMETHOXYBENZALDEHYDE
4460-86-0
Asaraldehyde
Asaronaldehyde
Asarylaldehyde
Benzaldehyde, 2,4,5-trimethoxy-
NSC 89299
NCI-C61632
CCRIS 1296
2,4,5-trimethoxy-benzaldehyde
HSDB 4502
UNII-NDU8J2Q00D
EINECS 224-713-3
2,4,5-trimethoxylbenzaldehyde
BRN 1951403
DTXSID1022217
AI3-36671
NSC-89299
DTXCID702217
4-08-00-02715 (Beilstein Handbook Reference)
TRIMETHOXYBENZALDEHYDE, 2,4,5-
2,4,5-TRIMETHOXYBENZALDEHYDE [HSDB]
3,4,6Trimethoxybenzaldehyde
Benzaldehyde, 2,4,5trimethoxy
2,4,5-TRIHYDROXYBENZALDEHYDE, 2,4,5-TRIMETHYL ETHER
iajbqayhsqiqre-uhfffaoysa-n
inchi=1/c10h12o4/c1-12-8-5-10(14-3)9(13-2)4-7(8)6-11/h4-6h,1-3h
Azarylaldehyde
Gazarin
3,4,6-Trimethoxybenzaldehyde
14374-62-0
MFCD00003312
NDU8J2Q00D
2,4,5-Trimethoxy benzaldehyde
NCGC00091253-05
SMR000112148
Acrolein(Propenal)
Spectrum_000818
Asaraldehyde (Standard)
Spectrum2_000386
Spectrum3_000170
Spectrum4_001759
Spectrum5_000618
2,5-Trimethoxybenzaldehyde
3,6-Trimethoxybenzaldehyde
Asaraldehyde (Asaronaldehyde)
BSPBio_001639
KBioGR_002238
KBioSS_001298
SPECTRUM200208
MLS002473312
MLS002695891
MLS006011864
2,4,5-Trimethoxybenzaldheyde
SCHEMBL333451
SPBio_000571
2,4,5-Trimethoxy-benzaldehyd
3,4, 6-Trimethoxybenzaldehyde
CHEMBL1164301
2,4,5-tri-methoxy benzaldehyde
KBio2_001298
KBio2_003866
KBio2_006434
KBio3_001139
CHEBI:113543
Asarylaldehyde, analytical standard
BCPP000436
HMS1922P08
HMS2268O16
HMS3656M12
HMS3884N06
BCP02914
NSC89299
Tox21_400070
BBL011033
CCG-38657
CK2093
s2531
STK802187
2,4,5-Trimethoxybenzaldehyde, 98%
AKOS000119399
AC-4247
BCP9000230
CS-6035
FT71343
HY-100580R
PS-6109
SDCCGMLS-0066425.P001
NCGC00091253-01
NCGC00091253-02
NCGC00091253-03
NCGC00091253-04
NCGC00091253-06
NCGC00091253-07
SY015794
2,4,5-Trimethoxybenzaldehyde, 9CI, 8CI
BCP0726000304
CAS-4460-86-0
DB-051236
HY-100580
NS00015122
SW219241-1
T1172
EN300-20248
AP-065/41884113
SR-05000002433
SR-05000002433-1
BRD-K88219015-001-02-5
BRD-K88219015-001-05-8
BRD-K88219015-001-10-8
Q27194435
F2190-0582
Z104477478
2,4,5-Trimethoxybenzaldehyde, Vetec(TM) reagent grade, 98%