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2,4,5-triphenylimidazole

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Identification
Molecular formula
C21H16N2
CAS number
2150-53-8
IUPAC name
2,4,5-triphenyl-1H-imidazole
State
State

In its standard state at room temperature, 2,4,5-triphenylimidazole is a solid.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.15
Boiling point (Celsius)
403.20
Boiling point (Kelvin)
676.35
General information
Molecular weight
333.41g/mol
Molar mass
333.4090g/mol
Density
1.3270g/cm3
Appearence

2,4,5-Triphenyl-1H-imidazole appears as a white to slightly off-white crystalline solid. It can be characterized by its crystalline structure, which may exhibit a fine, powdery consistency.

Comment on solubility

Solubility of 2,4,5-Triphenyl-1H-imidazole

2,4,5-Triphenyl-1H-imidazole is a fascinating compound with interesting solubility characteristics. Understanding the solubility of this compound can help elucidate its behavior in various chemical environments. Here are key points regarding its solubility:

  • Solvent Compatibility: 2,4,5-triphenyl-1H-imidazole is generally considered to be soluble in organic solvents, such as dichloromethane and ethyl acetate. This is attributed to its hydrophobic nature owing to the three phenyl groups.
  • Water Solubility: It exhibits poor solubility in water. The presence of the phenyl groups creates a steric hindrance that limits interaction with polar solvents, thereby reducing overall solubility.
  • Factors Influencing Solubility: The solubility of this compound can be influenced by factors such as:
    • Temperature: Increasing temperature may enhance solubility in organic solvents.
    • pH Levels: Although primarily neutral, alterations in pH can affect the ionization of related compounds, which can indirectly influence solubility.

In summary, while 2,4,5-triphenyl-1H-imidazole shows good solubility in select organic solvents, its hydrophobic characteristics keep it from dissolving well in water. This dual behavior highlights its potential applications in organic synthesis and medicinal chemistry.

Interesting facts

Interesting Facts about 2,4,5-Triphenyl-1H-Imidazole

2,4,5-Triphenyl-1H-imidazole is a remarkable compound that has garnered attention in various fields of research due to its unique structural and chemical properties. Here are some intriguing aspects of this imidazole derivative:

  • Structure and Stability: This compound features a heterocyclic imidazole ring complemented by three phenyl groups. The presence of these phenyl substituents contributes not only to the stability of the compound but also enhances its electronic characteristics, making it a fascinating subject for study.
  • Biological Relevance: Compounds featuring imidazole rings exhibit biological activities that make them valuable in pharmaceuticals. Research indicates that analogs of imidazole are involved in enzymatic processes and exhibit antifungal and anti-inflammatory properties.
  • Potential Applications: The unique electronic and optical properties of 2,4,5-triphenyl-1H-imidazole suggest potential applications in fields such as materials science, organic electronics, and photonic devices. Its ability to form complexes with metals also indicates its usefulness in coordination chemistry.
  • Synthetic Pathways: The synthesis of this compound often involves the use of various organic reactions, showcasing the versatility of organic chemistry methodologies. Techniques such as Friedel-Crafts acylation may be utilized to bring about the necessary modifications to the imidazole core.

The exploration of 2,4,5-triphenyl-1H-imidazole continues to be a promising area for scientists and researchers alike. Its versatility and biological significance make it a compound worth studying in detail, opening doors to new discoveries in both chemical and biological realms.

Synonyms
2,4,5-Triphenylimidazole
2,4,5-Triphenyl-1H-imidazole
Lophine
1H-Imidazole, 2,4,5-triphenyl-
EINECS 207-606-6
UNII-Q6K46G80ZD
NSC 62790
CCRIS 8668
Q6K46G80ZD
AI3-50036
NSC-62790
DTXSID3022039
DTXCID702039
rnipjyfzgxjsdd-uhfffaoysa-n
484-47-9
Lophin
IMIDAZOLE, 2,4,5-TRIPHENYL-
2,4,5-Triphenyl-1,3-imidazole
MFCD00005187
CHEMBL34173
2,5-Triphenylimidazole
Imidazole,4,5-triphenyl-
1H-Imidazole,4,5-triphenyl-
2,5-Triphenyl-1,3-imidazole
C21H16N2
TRIPHENDAZOLE
2,4,5-triphenylimidazol
ChemDiv1_027296
NCIOpen2_003361
Oprea1_374739
cid_10232
SCHEMBL104130
HMS664I16
2,4,5-Triphenylimidazole, 98%
2,4,5-Triphenyl-1H-imidazole #
NSC62790
NSC95931
BDBM50051887
NSC-95931
STL575101
AKOS002664609
CS-W009969
FT32358
HY-W009253
AS-18377
NCI60_008969
SY041522
DB-019821
NS00031796
T0999
EN300-1661101
SR-01000510787
SR-01000510787-1
SR-01000510787-2
Q11762376
Z57178689
F1204-0058