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Identification
Molecular formula
C7H5Br3O
CAS number
576-48-1
IUPAC name
2,4,6-tribromo-3-methyl-phenol
State
State

At room temperature, 2,4,6-Tribromo-3-methylphenol is in a solid state, notably as a stable crystalline powder, which retains its integrity under standard atmospheric conditions.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
344.83g/mol
Molar mass
344.8250g/mol
Density
2.3760g/cm3
Appearence

2,4,6-Tribromo-3-methylphenol appears as a white to off-white crystalline powder. It is typically noted for its distinct crystalline structure and lacks any significant color in its pure form.

Comment on solubility

Solubility of 2,4,6-Tribromo-3-methyl-phenol

2,4,6-Tribromo-3-methyl-phenol, known for its unique structural characteristics, exhibits interesting solubility properties. This compound's solubility can be influenced by several factors:

  • Polarity: The presence of multiple bromine atoms introduces significant polarity, affecting the compound's affinity for different solvents.
  • Hydroxyl Group: The hydroxyl (-OH) group increases hydrogen bonding potential, which may enhance solubility in polar solvents such as water.
  • Non-polar Solvents: Conversely, the bromine atoms also introduce hydrophobic characteristics, making the compound more soluble in non-polar solvents like hexane or toluene.

Generally, it can be stated that:

  • Soluble in organic solvents due to its non-polar regions.
  • Moderately soluble in water due to the hydrogen bonding capability of the phenolic hydroxyl group.

In summary, the solubility of 2,4,6-tribromo-3-methyl-phenol is a balance of its polar and non-polar features, making it particularly versatile when addressing various applications in chemical formulations.

Interesting facts

Interesting Facts about 2,4,6-Tribromo-3-methyl-phenol

2,4,6-Tribromo-3-methyl-phenol, often referred to as Triclosan, is a fascinating compound known for its diverse applications and significant role in various fields. Here are some interesting insights about this chemical:

  • Antimicrobial Properties: Triclosan is widely recognized for its antibacterial and antifungal properties, making it a common ingredient in a variety of personal care products, such as soaps, deodorants, and toothpaste.
  • Environmental Concerns: Despite its usefulness, Triclosan has raised environmental concerns due to its persistence and potential effects on aquatic life. Studies have suggested that it can accumulate in the environment, leading to increased scrutiny and regulation.
  • Mechanism of Action: This compound functions by inhibiting specific enzymatic pathways in bacteria, thereby preventing them from synthesizing fatty acids essential for their survival. As such, Triclosan is effective against a wide range of microorganisms.
  • Resistance Issues: There are ongoing debates regarding its contribution to antibiotic resistance in bacteria. Some studies have indicated that continuous use could promote resistance, sparking discussions among scientists and regulatory bodies.
  • Regulatory Bans: In recent years, several jurisdictions have enacted bans or restrictions on the use of Triclosan in consumer products, particularly in the United States. This decision reflects growing awareness about its potential health and environmental impacts.
  • History: Triclosan was first synthesized in 1964 and has since become a staple in antimicrobial formulations. Its widespread use made it one of the most researched compounds regarding safety and efficacy.

As a chemical student or scientist, it is essential to approach compounds like 2,4,6-tribromo-3-methyl-phenol with a balanced perspective, weighing their benefits against potential risks. Engaging in ongoing research helps illuminate the complexities surrounding such compounds, paving the way for safer alternatives in the future.

Synonyms
2,4,6-Tribromo-3-methylphenol
4619-74-3
Micatex
Triphysan
2,4,6-Tribromo-m-cresol
Triphysol
tribromometacresol
Phenol, 2,4,6-tribromo-3-methyl-
m-CRESOL, 2,4,6-TRIBROMO-
EINECS 225-032-4
NSC 74686
BRN 1949974
NSC-74686
Q3Z845166M
DTXSID40196754
3-06-00-01324 (Beilstein Handbook Reference)
2,4,6-TRIBROMO-M-CRESOL [MI]
2,4,6-TRIBROMO-M-CRESOL [WHO-DD]
DTXCID80119245
Phenol, 2,4,6-tribromo-3-methyl-(9CI)
225-032-4
3-Methyl-2,4,6-Tribromophenol
UNII-Q3Z845166M
2,6-Tribromo-m-cresol
m-Cresol,4,6-tribromo-
2,6-Tribromo-3-methylphenol
SCHEMBL467297
WLN: QR BE DE FE C1
CHEMBL3707340
Phenol,4,6-tribromo-3-methyl-
CHEBI:135457
2,4,6-Tribromo-m-cresol(oh=1)
NSC74686
AKOS015890412
DB13513
HY-W319335
AC-23681
DB-013956
CS-0358959
NS00031589
F20934
Q7840447