Skip to main content

2,5-bis(4-methoxy-3-nitrophenyl)-1,3,4-oxadiazole

ADVERTISEMENT
Identification
Molecular formula
C16H12N4O6
CAS number
33382-62-4
IUPAC name
2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole
State
State

The compound is in a solid state at room temperature. It is typically isolated as crystals or crystalline powder, which are stable under standard laboratory conditions.

Melting point (Celsius)
264.00
Melting point (Kelvin)
537.20
Boiling point (Celsius)
369.40
Boiling point (Kelvin)
642.50
General information
Molecular weight
354.31g/mol
Molar mass
354.3070g/mol
Density
1.4600g/cm3
Appearence

The compound 2,5-bis(4-methoxy-3-nitrophenyl)-1,3,4-oxadiazole typically appears as a crystalline solid with a pale yellow to yellowish color. The appearance is largely influenced by the nitro groups attached to the phenyl rings.

Comment on solubility

Solubility of 2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole

The compound 2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole exhibits some unique solubility characteristics that may influence its practical applications.

Key Points on Solubility:

  • Solubility in Organic Solvents: This compound is generally soluble in a variety of organic solvents, making it suitable for use in organic reactions and applications. Common solvents include:
    • Dimethyl sulfoxide (DMSO)
    • Ethanol
    • Acetone
    • Toluene
  • Water Solubility: It has limited solubility in water, which can hinder its use in aqueous systems. The presence of multiple hydrophobic aromatic groups contributes to this characteristic.
  • pH Influence: The solubility of this compound may vary with pH; conducting solubility tests in different pH environments could be beneficial, as acidic or basic conditions might enhance dissolution.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with higher temperatures, thus requiring heat application for optimal dissolution.

Understanding the solubility profile of this compound is crucial for scientists and researchers looking to utilize it effectively in various chemical contexts. As quoted from solubility theory, "like dissolves like," meaning the molecular structure significantly influences its interaction with solvents.

Interesting facts

Interesting Facts about 2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole

The compound 2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole is an intriguing member of the oxadiazole family, known for its diverse applications and unique structural properties. Here are some notable aspects:

  • Structural Significance: The presence of both the methoxy and nitro groups on the phenyl rings gives this compound notable electronic properties, often influencing its reactivity and interaction with light.
  • Potential Applications: Compounds of this class are explored for their potential applications in fields such as agriculture and material science, particularly as synthetic precursors to agrochemicals or as components in organic electronics.
  • Biological Activity: There is growing interest in the biological properties of oxadiazoles, with some studies suggesting potential anticancer and antimicrobial properties, making them a topic of investigation in medicinal chemistry.
  • Fluorescence: This compound may exhibit interesting photophysical properties, which could lead to its use as a fluorescent probe in various chemical and biological applications.
  • Research Opportunities: The unique characteristics of oxadiazoles invite extensive research. Whether through modifying substituents or exploring different synthetic pathways, there's plenty of room for innovation in this area.

This compound exemplifies the intersection of chemistry and application, showcasing how versatile structures can lend themselves to various innovative uses. As a chemistry student or a scientist, delving deeper into the properties and applications of 2,5-bis(4-methoxy-3-nitro-phenyl)-1,3,4-oxadiazole can lead to profound discoveries and insights.

Synonyms
BRN 1051952
2,5-Bis(4-methoxy-3-nitrophenyl)-1,3,4-oxadiazole
1,3,4-OXADIAZOLE, 2,5-BIS(4-METHOXY-3-NITROPHENYL)-
5306-39-8
DTXSID30201124
DTXCID30123615