Skip to main content

2,5-Dichloropyridine

ADVERTISEMENT
Identification
Molecular formula
C5H3Cl2N
CAS number
16164-05-7
IUPAC name
2,5-dichloropyridine
State
State

At room temperature, 2,5-dichloropyridine exists as a liquid. Its colorlessness or slight yellow hue and liquid state make it relatively easy to handle for various chemical synthesis processes requiring aromatic chlorinated compounds.

Melting point (Celsius)
3.00
Melting point (Kelvin)
276.15
Boiling point (Celsius)
210.50
Boiling point (Kelvin)
483.65
General information
Molecular weight
148.99g/mol
Molar mass
148.9920g/mol
Density
1.3710g/cm3
Appearence

2,5-Dichloropyridine is a colorless liquid with a pungent odor. It may appear slightly yellowish if impure. This compound is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.

Comment on solubility

Solubility of 2,5-Dichloropyridine

2,5-Dichloropyridine, with the chemical formula C5H3Cl2N, exhibits notable solubility characteristics that are critical for its application in various chemical processes. This organic compound is known to be:

  • Soluble in organic solvents: 2,5-Dichloropyridine is highly soluble in non-polar and weakly polar organic solvents such as alcohols, ethers, and chloroform.
  • Insoluble in water: This compound shows poor solubility in water due to its hydrophobic characteristics, which limits its interactions with polar molecules.
  • Temperature Dependent: Like many organic compounds, its solubility may vary with temperature; generally, increased temperature can enhance solubility in organic solvents.

In terms of application, understanding the solubility of 2,5-dichloropyridine is key for its use in synthesis or reactions where solubility may influence the reaction kinetics or equilibria. As noted in various studies, the solubility properties play a fundamental role in determining how well this compound can be integrated into chemical reactions.

Overall, while 2,5-dichloropyridine’s solubility in organic solvents is a valuable asset, its limitation in aqueous solutions is significant for projects involving water-sensitive methods. Taking these factors into account can help chemists effectively plan and execute reactions involving this intriguing compound.

Interesting facts

Interesting Facts about 2,5-Dichloropyridine

2,5-Dichloropyridine is an exciting compound with versatile applications in both organic synthesis and agricultural chemistry. Here are some noteworthy aspects of this intriguing molecule:

  • Unique Structure: As a chlorinated derivative of pyridine, 2,5-dichloropyridine features 2 and 5-positions occupied by chlorine atoms. This substitution pattern introduces distinct properties that influence its reactivity and interactions.
  • Pharmaceutical Applications: This compound has been explored for its potential in pharmaceutical chemistry. It serves as a key building block in the synthesis of various biologically active compounds. Researchers have shown interest in its derivatives for their promising roles in drug development.
  • Pesticide Use: Due to its biocidal properties, 2,5-dichloropyridine is utilized in the formulation of herbicides and insecticides. Its effectiveness against a range of pests makes it a valuable asset in modern agriculture aimed at enhancing crop yields.
  • Solvent Properties: As a solvent, it can dissolve a variety of organic compounds, making it useful in various chemical reactions and extractions, especially those involving polar solvents.
  • Research and Development: Scientists continue to investigate the reactivity of 2,5-dichloropyridine. Its ability to participate in various organic reactions, such as nucleophilic substitutions and coupling reactions, makes it a subject of ongoing research in synthetic organic chemistry.

In summary, 2,5-dichloropyridine is not just a simple compound; it embodies a world of possibilities in agriculture, pharmaceuticals, and organic synthesis. As the field of chemistry advances, the importance of such compounds in developing innovative solutions will undoubtedly grow.

Synonyms
2,5-DICHLOROPYRIDINE
16110-09-1
Pyridine, 2,5-dichloro-
CCRIS 1718
EINECS 240-278-2
NSC 528661
BRN 0108886
FZ623S5E22
NSC-528661
DTXSID7051765
DTXCID0030320
240-278-2
MFCD00006239
2,5-Dichloro-pyridine
2,5-Dichloro Pyridine
NSC528661
2,5-dichloropyridin
2,5-dichioropyridine
2.5-dichloropyridine
2,5 Dichloropyridine
2,5-dichloro-pyridin
2,5 -dichloropyridine
2-chloro-5-chloropyridine
WLN: T6NJ BG EG
SCHEMBL17800
2,5-Dichloropyridine, 98%
SCHEMBL193034
SCHEMBL193503
SCHEMBL193743
UNII-FZ623S5E22
orb2940207
SCHEMBL29538085
BCP22170
STR04178
SBB054354
AKOS000431451
AB00654
AC-7008
CS-W016342
FD05298
HY-W015626
PS-5116
DB-025131
D1607
NS00025254
EN300-21351
F0001-0578
InChI=1/C5H3Cl2N/c6-4-1-2-5(7)8-3-4/h1-3